Generalized lock-in amplifiers use digital cavities with Q-factors as high as 5 × 108 to measure signals with very high precision. In this Note, we show that generalized lock-in amplifiers can be used to analyze microwave (giga-hertz) signals with a precision of few tens of hertz. We propose that the physical changes in the medium of propagation can be measured precisely by the ultra-high precisio

At the close of the Fourth International Polar Year, we take stock of the ecological consequences of recent climate change in the Arctic, focusing on effects at population, community, and ecosystem scales. Despite the buffering effect of landscape heterogeneity, Arctic ecosystems and the trophic relationships that structure them have been severely perturbed. These rapid changes may be a bellwether

The inclusive jet cross-section has been measured in proton-proton collisions at root s = 2.76 TeV in a dataset corresponding to an integrated luminosity of 0.20 pb(-1) collected with the ATLAS detector at the Large Hadron Collider in 2011. Jets are identified using the anti-k(t) algorithm with two radius parameters of 0.4 and 0.6. The inclusive jet double-differential cross-section is presented a

Unit verification, including software inspections and unit tests, is usually the first code verification phase in the software development process. However, principles of unit verification are weakly explored, mostly due to the lack of data, since unit verification data are rarely systematically collected and only a few studies have been published with such data from industry. Therefore, we explor

On the basis of a panel study in rural Tamil Nadu, some analytical and comparative studies across India, and the ARIS-REDS survey, I discuss the changing scenario of rural change, the growth of non-farm activities and income, and State interventions until the first decade of the twenty-first century. The overall conclusion is that there are strong evidences of a slow but stable growth of income wi

Biosensors would benefit from further miniaturization, increased detection rate and independence from external pumps and other bulky equipment. Whereas transportation systems built around molecular motors and cytoskeletal filaments hold significant promise in the latter regard, recent proof-of-principle devices based on the microtubule-kinesin motor system have not matched the speed of existing me

In order to ensure that ovarian cancer patients access appropriate treatment to improve the outcome of this disease, accurate characterization before any surgery on ovarian pathology is essential. The International Ovarian Tumor Analysis (IOTA) collaboration has standardized the approach to the ultrasound description of adnexal pathology. A prospectively collected large database enabled previously

A cotton skin and a waterproof but permeable Gore-Tex skin were designed for the thermal manikin “Tore” to simulate different sweating styles (the wet cotton skin inside and Gore-Tex skin outside to simulate the sweating style of thermal manikin “Walter”, and Gore-Tex skin inside with wet cotton skin outside to simulate the sweating style of thermal manikins “Newton”). The evaporative resistances

Objectives: The aim of the study was to illuminate the experience of life as next of kin to an elderly person with cancer. Background: Being next of kin to an elderly person with cancer and its impact on everyday life has been sparsely researched. Such understanding is needed to support both the sufferers and their relatives in dealing with issues arising after a cancer diagnosis in old age. Desig

Life on Earth was sharply disrupted 66 Ma ago as an asteroid hit the sea-floor in what is today Yucatan Peninsula, Mexico. Approximately 600 km(3) of sedimentary rock were vapourized, ejected into the atmosphere and subsequently deposited globally as an ejecta apron and fallout layer. Proximal ejecta deposits occur in Belize and southern Mexico where the so called Albion island spheroid bed is sup

Lightweight wooden-framed constructions have steadily increased their market share in Sweden during the last two decades. Achieving acoustic and vibration comfort in wooden-based buildings is, however, still a challenging task. Wood is high in both strength and stiffness in relation to its weight, but its variability has repercussions on how sound propagates, this triggering sound insulation probl

Despite the ever-growing literature on various aspects of the Kurdish question in Turkey, there are practically no normative discussions of Kurdish demands for the public recognition of their identities. This is all the more startling given the ascendancy of philosophical accounts in the literature on minority rights. This article will try to redress the balance by proposing a normative framework

Most deterioration processes in cement based materials are closely related to moisture sorption and moisture transport properties. Therefore, it is important to study these properties, both theoretically and practically. This work is an experimental investigation in this field. Nowadays, the cement industry produces cements with increasing amounts of supplementary cementitious materials (SCMs) to

Popular Abstract in Swedish Hjärtsjukdom som orsakas av skador på hjärtmuskelceller är en av de vanligaste dödsorsakerna världen över. En framtida önskvärd behandling vore att kunna stimulera kroppens egna förmåga att återskapa hjärtmuskelceller, eller att isolera hjärtmuskelceller framställda i cellkultur. Arbete I är fokusera på studier rörande tillväxtmönstret hos hjärtmuskelceller under normaHeart disease results from the loss of cardiomyocytes following myocardial damage and is a leading cause of death worldwide. Stimulating the endogenous regeneration of cardiomyocytes or isolating them from in vitro culture is an attractive therapeutic strategy. In paper I, the focus is on the cellular growth patterns of murine cardiomyocytes under steady-state conditions. The turnover of cardiomyo

Background: Exhaled breath temperature (EBT) has been suggested as a marker of airway inflammation in asthma. Objectives: The aim of the present study was to investigate EBT in asthmatic subjects compared to healthy controls after an exercise challenge test, and in subjects with exercise-induced bronchoconstriction compared to subjects without, and to compare with body temperatures. Methods: A tot

Context: Due to the complexity and challenging nature of radical prostatectomy (RP), it is likely that both short-and long-term outcomes strongly depend on the cumulative number of cases performed by the surgeon as well as by the hospital. Objective: To review systematically the association between hospital and surgeon volume and perioperative, oncologic, and functional outcomes after RP. Evidence

Nuclear orphan receptor TLX (Drosophila tailless homolog) is essential for the maintenance of neural stem/progenitor cell self-renewal, but its role in neuroblastoma (NB) is not well understood. Here, we show that TLX is essential for the formation of tumor spheres in three different NB cell lines, when grown in neural stem cell media. We demonstrate that the knock down of TLX in IMR-32 cells dimi