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The aim of this study was to evaluate the contribution of a low calcium diet to the cortical and trabecular osteoporosis seen in ovariectomized rats after 7 weeks on a low calcium diet and to investigate the effects of the bisphosphonate clodronate on this development of osteoporosis. Thirty-six mature, female Wistar rats were randomized into four groups: Ovx-B (bisphosphonate) and Ovx-C (control)
Leonard Talmy’s influential binary motion event typology has encountered four main challenges: (a) additional language types; (b) extensive “type-internal” variation; (c) the role of other relevant form classes than verbs and “satellites;” and (d) alternative definitions of key semantic concepts like Motion, Path and Manner. After reviewing these issues, we show that the theory of Holistic Spatial
Cancer research has transformed our view on cellular mechanisms for oxygen sensing. It has been documented that these mechanisms are important for maintaining animal tissues and life in environments where oxygen (O2) concentrations fluctuate. In adult animals, oxygen sensing is governed by the Hypoxia Inducible Factors (HIFs) that are stabilized at low oxygen concentrations (hypoxia). However, the
Background: Current equations for estimated glomerular filtration rate (eGFR) that use serum creatinine or cystatin C incorporate age, sex, and race to estimate measured GFR. However, race in eGFR equations is a social and not a biologic construct.Methods: We developed new eGFR equations without race using data from two development data sets: 10 studies (8254 participants, 31.5% Black) for serum c
This master’s thesis explored how the incorporation of cricket flour into a seitan-based product affected the physical properties and sensory attributes, including taste, texture, smelll and appearance, based on consumer sentiment. The project aimed to develop a high protein, “Entomo-vegan” base-product in collaboration with the food company Eat:em, using crickets as a sustainable protein source.
Passenger journeys increasingly include mediality in its various manifestations. Mass-transit systems need clear signs, often featured in the form of audiovisual media, and transmitted through displays working for captive and in-transit audiences. With reference to Italian biggest railway stations, the chapter explores the reconfiguration of those television-like networks (commonly known as ‘go-tv
The environmental effects of the widespread use and production of plastic have gained attention in recent years. Plastic pollution in marine environments, and limitations to systems of circularity and recycling, are increasingly recognised as serious global problems. Policies and governance around plastic are thus expected to expand in scope. This article examines the Swedish public’s opinions on
Background: The ongoing pandemic is having a collateral health effect on delivery of surgical care to millions of patients. Very little is known about pandemic management and effects on other services, including delivery of surgery. Methods: This was a scoping review of all available literature pertaining to COVID-19 and surgery, using electronic databases, society websites, webinars and preprint
Impaired mitochondrial translation or reduced mitochondrial protein import can lead to imbalances in mitochondrial protein composition. Such mitochondrial proteotoxic stresses can trigger a nuclear transcriptional response commonly described as the mitochondrial unfolded protein response (UPRmt). Despite extensive studies of UPRmt pathways in animal and fungal systems, very little is known about h
In contrast to artificial systems, animals must forage for food. In biology, the availability of energy is typically both precarious and highly variable. Most importantly, the very structure of organisms is dependent on the continuous metabolism of nutrients into ATP, and its use in maintaining homeostasis. This means that energy is at the centre of all biological processes, including cognition. S
Background: Infertile men with non-obstructive azoospermia (NOA) have impaired spermatogenesis. Dilated and un-dilated atrophic seminiferous tubules are often present in the testes of these patients, with the highest likelihood of active spermatogenesis in the dilated tubules. Little is known about the un-dilated tubules, which in NOA patients constitute the majority. To advance therapeutic strate
Many scholars have regarded China's emergence as an economic force as a threat to democracy in Africa, presenting China as the exporter of an authoritarian model through its rising economic influence. This article investigates how well founded the contended Chinese economic threat to Africa is by both analyzing the data at a very fundamental level and applying time-series, cross-sectional analysis
Definition of older age in AML is arbitrary. In the context of the clinical studies, it starts with age ≥ 60 or ≥65 years and in recent years ≥70 or 75, depending on the selection of the studied population. In clinical practice, with older age we often mean that the patient is unfit for intensive chemotherapy. Higher age overlaps with categories such as worse performance status, unfitness, co-morb
In what ways can various perspectives, aims, circumstances, and directives influence music students and music teachers in different educational contexts such as primary school, Schools of music and performing arts (SMPA), folk high school, and upper secondary school, viewed from a Nordic perspective?A common characteristic for all these types of schools is that they can be part of an educational a
Background: Persistent non-plateauing adverse event rates in patients who underwent percutaneous coronary intervention (PCI) remain a challenge. A bioadaptor is a novel implant that addresses this issue by restoring the haemodynamic modulation of the artery, allowing cyclic pulsatility, vasomotion, and adaptative remodelling, by unlocking and providing dynamic support to the artery. We aimed to as
Ultra-safe organizations, such as Air Navigation Service Providers (ANSPs), have extensive safety management organizations and generally excellent safety records with very few serious incidents and accidents. This development has been supported by increasingly advanced and effective methods. However, recent research has uncovered how the application of even advanced incident investigation methods
A key aspect of an attractive and accessible public transport system is that passengers feel safe and secure, not least from a travel chain perspective. The aim of this paper is to provide an increased understanding of triggers for feelings of insecurity and perceptions of safety in relation to public transport, with a special focus on larger public transport nodes in the city of Malmö, Sweden. Th
Hydropower is one of the renewable energy sources that can play a crucial role to fulfil the global energy demand. However, the performance of the hydro turbine is severely affected by silt erosion and cavitation problems which causes a reduction in the overall efficiency of the plant. Various studies have been carried out and are available in the literature to investigate silt erosion and cavitat
