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Identification and relative quantification of hundreds to thousands of proteins within complex biological samples have become realistic with the emergence of stable isotope labeling in combination with high throughput mass spectrometry. However, all current chemical approaches target a single amino acid functionality (most often lysine or cysteine) despite the fact that addressing two or more amin
In 2014, leadership studies saw the retraction of a number of journal articles written by prominent researchers who are closely associated with popular concepts such as transformational leadership, authentic leadership, ethical leadership and spiritual leadership. In response, The Leadership Quarterly published a lengthy editorial that presented these retractions as a sign of health in a mature sc
It was estimated that about 0.5% of the world’s population is in need of assistive devices; in 2013, the number of people who required such aid was estimated at 25 million in Africa and Asia. The majority of these people could have increased their participation within society by receiving an assistive device to facilitate mobilisation, recognised as a step in accessing basic human rights such as f
Hereditary nonpolyposis colorectal cancer (HNPCC) is caused by a germline mutation in one of several DNA repair genes, which in the tumors is reflected as microsatellite instability (MSI). MSI+ tumors have been found to carry somatic frameshift mutations in mononucleotide repeats within the coding regions of several genes involved in growth control, apoptosis, and DNA repair, e.g., TGFBRII, BAX, I
Introduction: Few large studies have examined the heritability of venous thromboembolism (VTE). Moreover, twin studies have been suggested to overestimate heritability. The aim of the present study was to determine the heritability nationwide in the general Swedish population using full siblings and half-siblings. Methods: VTE was defined using the Swedish patient register. Full sibling (FS) and h
An important issue in clinical neural grafting is whether a second instriatial allograft can survive well in a patient who has received an allograft before. In this study, the survival, immunogenicity and function of intrastriatal grafts of allogeneic or syngeneic embryonic dopamine-rich tissue in rats which had previously received either an intrastriatal allo- or syn-graft or sham injections were
Small heat shock proteins (sHsps) are found in all organisms and evolved early in the history of life, prior to the divergence of the three domains of life (Archaea, Bacteria, and Eukarya). Their malfunction is connected to several different diseases in humans, such as Alzheimer’s and Parkinson’s disease. sHsps are especially abundant in plants, where most are highly upregulated as the first line
Gas exchange in fruits, in particular oxygen transport in apples, was studied non-intrusively using wavelength modulation diode laser absorption spectroscopy at about 761 run, applied to the strongly scattering intact fruit structure. The applicability of the technique was demonstrated by studies of the influence of the skin to regulate the internal oxygen balance and of cling film in modifying it
The continual interaction between economic change and economic policies designed to manage or guide this change seldom finds such dramatic expression as when one type of economy replaces another, e. g., when the industrial economy replaces the agrarian or is in turn supplanted by the “post-industrial” economy.Thus, when the American economy was in the thick of its industrial revolution during the
This paper presents a calibration technique for massive MIMO base stations, where the frequency responses of the transmit and/or receive analog front-ends are individually estimated and compensated for. Calibration is achieved by a first-round of channel sounding between base station antennas, followed by post-processing and a compensation stage. The proposed technique is general in the sense that
This thesis examines the extent to which lobbyists bring democratic value to the policy-formulation and decision-making stages of the EU policy process. It is examined through a single case study of the amendment of Directive 2001/83/EC. By adopting an actor-centered institutionalism perspective and through theoretical discussion on Robert Keohane, Fritz Scharpf and Pieter Bouwen, this thesis bui
Syftet med föreliggande uppsats är att utreda huruvida ockerparagrafen er-bjuder ett effektivt skydd mot tvångsarbete i Sverige och om så inte är fallet utreda förutsättningarna för en ny kriminalisering. För att uppfylla syftet utreds hur tvångsarbete definieras och vilket eller vilka skyddsintressen som aktualiseras. Vidare utreds om ockerparagrafen är utformad på ett effektivt sätt för att skydThe purpose with this paper is to examine whether or not the usury clause offers a satisfactory protection against forced labor in Sweden and if so is not the case investigate the prerequisites for a new criminalization. To com-plete the purpose a definition of forced labor is performed and what or which protective interests that are prevalent. The paper also discuss if the usury clause is designe
Att polisen använder sig av provokativa åtgärder i brottsbekämpningen är i viss mån accepterat i Sverige. Brottsprovokation och bevisprovokation anses vara nödvändiga metoder för att bekämpa allvarlig och organiserad brottslighet och har blivit ett allt vanligare inslag i polisens arbete sedan början av 1980-talet. Sedan dess har även en förändring skett vad gäller inställningen till den provoceraThe use of provocative investigative measures is in Sweden an accepted method in the control of crime. These measures are considered to be essential parts in the fight against serious and organized criminality and have become a more commonly used instrument for the police since the early 1980’s. Since then, there has been a change concerning how a criminal is treated legally after being subject to
According to the EU Water Framework Directive, all Member States are obliged to survey and analyze their water according to river basins. The directive was implemented into Swe-dish law in 2004. At the same time, Sweden's five water authorities were formed to coordi-nate the water management at regional and municipal levels. Furthermore, the municipalities in Sweden are imposed to develop muni
Historiskt sett har människor byggt sina hus med de material som den omgivande naturen gav. Både vass och lera är två sådana material som förekommer naturligt. Det som bl.a. skiljer dessa material åt är de processer som krävs för att de ska kunna användas som taktäckningsmaterial. Vassen skördas och torkas medan leran bearbetas och bränns för att slutligen bli en användbar produkt. I tidigare svenHistorically, people built their houses with the materials that the surrounding nature gave. Reeds and clay are two such materials occurring naturally. A difference between these materials is the processes required for them to be used as roofing material. Reed is harvested and then dried while the clay is processed and fired to finally become the useful product. In earlier Swedish history roofs we
Den här uppsatsen handlar om tillämpningen av barnets bästa i vårdnadstvister som föregåtts av umgängessabotage. När vårdnaden om ett barn ska beslutas ska avgörandet göras efter vad som är barnets bästa. Umgängessabotage utgör en omständighet av särskild betydelse i avvägningen mellan olika intressen som alla kan tala för barnets bästa. Därtill är ett barns bästa inte alltid det bästa för ett annThe purpose of this paper is to examine the adjudication of the child's best interest in custody trials preceded by one parent preventing the other parent from contact with the child. In custody trials, the best interest of the child is always the primary consideration. Preventing the other parent from contact with the child constitute a circumstance of particular importance in the determinati
Medlingsinstitutet är en alternativ konflikthantering där parterna ges möjlighet att påverka konfliktens lösning och att återställa lugnet parterna emellan. Transaktioner är inte alltid friktionsfria och situationer kan uppstå där en av parterna vill föra saken inför domstol. Det är inte ovanligt att ombud i dessa situationer hotar om stämning som en skrämseltaktik för att ge sin part en hävstång.The Mediation Institute is a form of dispute resolution alternative to the judicial process where the parties may impact with the process and can influence the outcome, all in the purpose of restoring the calm between the parties. Transactions are not always successful and may result in a dispute where one party is inclined to take the dispute to court. It is not unusual that a part’s lawyer uses
This project explored the usage and effectiveness of a natural water filtration system using xylem from Picea Abies, or Norway Spruce. The project is concentrated on the region of southeast and south Asia where people suffer from water contamination, providing a concept of a water filter with comprehensive protection against waterborne diseases. The study implemented secondary research on product
An electrochemical biosensor based on ZnO nanorods for potentiometric cholesterol determination is proposed. Hexagon-shaped ZnO nanorods were directly grown on a silver wire having a diameter of 250 mu m using low temperature aqueous chemical approach that produced ZnO nanorods with a diameter of 125250 nm and a length of similar to 1 mu m. Cholesterol oxidase (ChOx) was immobilized by a physical
