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BACKGROUND: Children are being infected by HIV/AIDS mainly through mother-to-child transmission. In Ethiopia currently more than 135,000 children are living with HIV/AIDS. The aim of this study was to describe the pattern of ARV uptake after birth, co-trimoxazole prophylaxis and follow up compliance, and to examine which factors are associated with the intervention outcome.METHODS: A retrospective
Axonal injury is a hallmark of traumatic brain injury (TBI) and is associated with a poor clinical outcome. Following central nervous system injury, axons regenerate poorly, in part due to the presence of molecules associated with myelin that inhibit axonal outgrowth, including myelin-associated glycoprotein (MAG). The involvement of MAG in neurobehavioral deficits and tissue loss following experi
Solving the mystery of the origin of chondrules is one of the most elusive goals in the field of meteoritics. Recently, the idea of planet(esimal) collisions releasing splashes of lava droplets, long considered out of favor, has been reconsidered as a possible origin of chondrules by several papers. One of the main problems with this idea is the lack of quantitative and simple models that can be u
An asymptomatic Atrial Septal Defect (ASD) is often closed at the age of 3–5 years using a transcatheter or surgical technique. Symptomatic ASD or ASD associated with pulmonary hypertension (PHT) may require earlier closure, particularly in combination with other non-cardiac risk factors for PHT, but the indications for early closure and the potential risk for complications are largely unknown. Th
A growing body of literature on the 2019 novel coronavirus (SARS-CoV-2) is becoming available, but a synthesis of available data has not been conducted. We performed a scoping review of currently available clinical, epidemiological, laboratory, and chest imaging data related to the SARS-CoV-2 infection. We searched MEDLINE, Cochrane CENTRAL, EMBASE, Scopus and LILACS from 01 January 2019 to 24 Feb
Foot problems complicating diabetes are a source of major patient suffering and societal costs. To prevent, or at least reduce, the adverse effects of foot problems in diabetes, the International Working Group on the Diabetic Foot (IWGDF; www.iwgdf.org) was founded in 1996, consisting of experts from almost all the disciplines involved in the care of patients with diabetes and foot problems. An im
High-risk (HR) human papillomavirus (HPV) infection is an established cause of malignant disease. We used a societal perspective to estimate the cost of HR HPV-related cervical, vulvar, vaginal, anal, and penile precancer and cancer, and oropharyngeal cancer in Sweden in 2006, 1 year before HPV vaccination became available in the country. Materials and methods This prevalence-based cost-of-illness
Background: The Tau PET ligand 18F-AV1451 has been shown to reliably detect paired helical filaments of tau in Alzheimer's disease, but it is not yet known whether it binds to the tau aggregates present in patients with mutations in the gene (MAPT) coding for the tau protein. Further, no study has yet compared the cerebral retention of 18F -AV1451 with the tau aggregates revealed using neuropathol
This study presents a 2-yr follow-up of 281 patients, aged 15-34 yr, diagnosed with diabetes between 1992 and 1993. At diagnosis, 224 (80%) patients were positive for at least one of the following autoantibodies: islet cell antibodies (ICAs), glutamic acid decarboxylase antibodies (GADAs), or tyrosine phosphatase antibodies (IA-2As); the remaining 57 (20%) patients were negative for all three auto
We conducted pooled and meta-analyses of the association of the calpain-10 gene (CAPN10) polymorphisms SNP-43, Indel-19 and SNP-63 individually and as haplotypes with type 2 diabetes (T2D) in 3237 patients and 2935 controls of European ancestry. In the pooled analyses, the common SNP-43*G allele was associated with modest but statistically significant increased risk of T2D (odds ratio (OR) = 1.11
Comparative genomic hybridization (CGH) analysis has shown that chromosome 5q deletions are the most frequent aberration in breast tumors from BRCA1 mutation carriers. To map the location of putative 5q tumor suppressor gene(s), 26 microsatellite markers covering chromosome 5 were used in loss of heterozygosity (LOH) analysis of breast tumors from BRCA1 (n = 42) and BRCA2 mutation carriers (n = 67
Background: The K3326X variant in BRCA2 (BRCA2∗c.9976A>T p.Lys3326∗rs11571833) has been found to be associated with small increased risks of breast cancer. However, it is not clear to what extent linkage disequilibrium with fully pathogenic mutations might account for this association. There is scant information about the effect of K3326X in other hormonerelated cancers. Methods: Using weighted lo
Två grundläggande rättsgrundsatser inom civilprocessrätten är principen om jura novit curia och kontradiktionsprincipen. Jura novit curia innebär att domstolen känner lagen och att domstolen ska tillämpa den adekvata rättsregeln på tvisten, oavsett om parterna baserat sin talan på denna eller ej. Kontradiktionsprincipen, som både finns i intern svensk rätt och i EKMR, stadgar att ingen får dömas oTwo fundamental principles in the Swedish procedural code are the principle iura novit curia and the principle of an adversarial procedure. Iura novit curia means that the court knows the law and that the judge is responsible for the application of the relevant legal rules, whether the parties have based their pleadings on these or not. The principle of an adversarial procedure, which exists both
Popular science summary Ortho Group SEARCH A gene is a unit of heredity of a living species. Genes are transferred from one generation to the next by vertical descent. Two genes are homologous if derived from a common ancestral gene. Homologous genes related by duplication event within the genome are paralogous genes. Copies of the same ancestral gene separated by a speciation event (when a spec
Hedersrelaterat våld är för svenskt vidkommande inte längre ett främmande begrepp eller fenomen. Inte desto mindre är ämnet politiskt laddat och debatten om hedersrelaterat våld är fortfarande högaktuell. Inte minst på det straffrättsliga området gör sig problematiken gällande och det tycks råda en oklarhet kring vilken betydelse heder bör ha i rättsliga sammanhang. Hedersrelaterat våld är ett kViolence in the name of honour is no longer an unknown concept or phenomenon in the Swedish society. Nevertheless, the issue is subject of an ongoing political debate. The problematic aspects of violence in the name of honour are evident within the criminal justice system and there appears to be inherent uncertainties regarding the role of honour in the legal context. Violence in the name of hon
The purpose of this master’s thesis is to provide a contribution to the research body regarding consumer returns, particularly within the online fashion retail industry. A quantitative data analysis approach is chosen and two main methods are used: data study that aims to identify patterns and interesting relationships in the data, and a simulation study that uses real input data to attempt to ide
År 1979 införde Sverige ett uttryckligt agaförbud. Stadgandet i 6 kap. 1 § föräldrabalken, (FB) innebär att föräldrar inte får utsätta barn för kroppslig bestraffning eller annan kränkande behandling. Agaförbudet är en markering från lagstiftarens sida om att barn är extra skyddsvärda. Enligt motiven till 6 kap. 1 § FB är det dock oundvikligt att föräldrar erkänns rätten att övervinna fysiskt motsIn year 1979 a ban on corporal punishment was introduced in Swedish law. According to Children and Parents Code (CPC), parents cannot practice any form of physical punishment upon their children. Hence, the ban on corporal punishment can be considered a clear statement declaring that the protection of children is a matter of high relevance in the Swedish society. However, there is an ambiguity in
Rätten att få använda straffprocessuella tvångsmedel är viktig och nödvändig för de brottsutredande myndigheterna för att uppnå så effektiv brottsbekämpning som möjligt. Exempel på typiska straffprocessuella tvångsmedel är häktning, anhållande samt husrannsakan, alla innebär en integritetskränkning för den som utsätts för de. När det gäller hemliga tvångsmedel är de att anse som mer integritetskräThe right to use pre-trial coercive measures is important and necessary for the investigating authorities in the objective of achieving the most effective law enforcement possible. Examples of typical criminal coercive measures are detention, arrest and raids, all of which violate the privacy of the victim. Examples of secret coercive measures are secret telemonitoring and secret telephone tapping
Gängkriminaliteten har under det senaste decenniet ökat i Sverige och hårdare tag har efterfrågats. Tidöavtalet anger att det är av högsta vikt att bekämpa gängkriminaliteten i Sverige och i början på 2023 lämnade regeringen in en proposition till riksdagen som bland annat föreslog straffskärpningar för vissa straffskalor för brottstyper som är vanliga inom kriminella nätverk. Enligt propositionenThe past decade has witnessed a rise in gang-related violence and crime in Sweden, which has caused a debate prompting calls for more stringent measures. In early 2023, the government submitted a proposition to the parliament which included proposals for stricter penalties för certain crime categories commonly associated with criminal networks. According to the proposition, increased penalty scale
I svensk straffprocessrätt har omedelbarhetsprincipen haft stor betydelse sedan rättegångsbalken infördes år 1948. Den innebär att domstolen bara ska döma över det som har framkommit under huvudförhandlingen. Domstolen har inte innan huvudförhandlingen läst polisens utredning, utan parter och vittnen ska komma till domstolen och lämna sin berättelse direkt inför rätten. Den 1 januari 2022 infördeIn Swedish criminal procedure law, the principle of immediateness has been of great significance since the code of judicial procedure came into effect in 1948. This implies that the court should only judge and present verdicts based on what has appeared during the main hearing. Hence, the court will not have read the pre-trial investigation before the main hearing. Instead, the implicated parties
