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The Upper Paraná River Basin (UPRB) has undergone remarkable land use and cover changes (LUCC) in recent decades. This paper analyses the hydrologic response to LUCC in the UPRB between 1985 and 2015, using the Soil and Water Assessment Tool (SWAT) model. The impacts of LUCC were examined for annual, wet, and dry season (both during calibrated and validated periods) between 1984 and 2015. The most
This paper aims to study what influence different meteorological parameters have on the radial tree growth of Scots pine (Pinus sylvestris L.) in peat and mineral soils, as well as to make predictions of radial tree growth responses to changing climate based on various future climate projections. Four Lithuanian peatland complexes representing different geographical settings and hydrological condi
Dendritic cells (DCs) are potent antigen-presenting cells that might play contradictory roles during HIV-1 infection, contributing not only to antiviral immunity but also to viral dissemination and immune evasion. Although DCs are characterized by enormous functional diversity, it has not been analyzed how differentially programmed DCs interact with HIV-1. We have previously described the reprogra
Objective: Nuclear receptor interacting protein 1 (NRIP1) is an important energy regulator, but few studies have addressed its role in humans. This study investigated adipose tissue and skeletal muscle NRIP1 gene expression and serum levels in response to weight loss and exercise in humans. Methods: NRIP1 expression was measured by microarray and serum NRIP1 by ELISA and Western blotting. Skeletal
Study objective: We aim to describe the variability and identify gaps in preparedness and response to the coronavirus disease 2019 pandemic in European emergency departments (EDs) caring for children. Methods: A cross-sectional point-prevalence survey was developed and disseminated through the pediatric emergency medicine research networks for Europe (Research in European Pediatric Emergency Medic
Monoterpenes emitted from plants have an important role in atmospheric chemistry through changing atmospheric oxidative capacity, forming new particles and secondary organic aerosols. The emission rates and patterns can be affected by changing climate. In this study, emission responses to six years of climatic manipulations (elevated CO2, extended summer drought and night-time warming) were invest
Objective. To investigate baseline levels of 12 serum biomarkers that constitute a multibiomarker disease activity test, as predictors of response to methotrexate (MTX) in patients with early rheumatoid arthritis (eRA). Methods. In 298 patients from the Swedish Pharmacotherapy (SWEFOT) clinical trial, baseline serum levels of 12 proteins were analyzed for association with disease activity based on
Polarised neutron beams are used in disciplines as diverse as magnetism,soft matter or biology. However, most of these applications often suffer from low flux also because the existing neutron polarising methods imply the filtering of one of the spin states, with a transmission of 50% at maximum. With the purpose of using all neutrons that are usually discarded, we propose a system that splits the
SQSTM1/p62 is an autophagic receptor that plays a major role in mediating stress and innate immune responses. Preclinical studies identified p62 as a target of the prototype innate defense regulator (IDR); however, the molecular mechanism of this process remains unclear. Here, we describe the structural basis and biological consequences of the interaction of p62 with the next generation of IDRs, d
The purpose of this paper is to show that shortcomings exist in the plasticity induced damage theories. Existing phenomenological thermodynamic approaches used for describing elasto-plasticity coupled with damage are therefore evaluated. Within the concept of effective stress both the postulate of strain equivalence and the postulate of (complementary) energy equivalence, as well as extensions of
Quantum dots are useful model systems for studying quantum thermoelectric behavior because of their highly energy-dependent electron transport properties, which are tunable by electrostatic gating. As a result of this strong energy dependence, the thermoelectric response of quantum dots is expected to be nonlinear with respect to an applied thermal bias. However, until now this effect has been cha
Purpose: People with acquired brain injury (ABI) have difficulties using everyday technology (ET) in daily tasks at home and in society. To support them in managing the demands imposed by using ET, knowledge is needed concerning their response actions to the difficulties. The aim of this study was to explore and describe what characterizes response actions to difficulties using ET, their condition
Background. Splenectomy is accompanied by a life-long risk of overwhelming postsplenectomy infection (OPSI), mainly caused by polysaccharide (PS) encapsulated bacteria such as Streptococcus pneumoniae. Despite extensive prophylactic efforts the mortality and morbidity rates remain high. The present study was based on a strategy with a predefined vaccination algorithm including repeated 23-valent p
