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Engineering Design Integration & Non-Destructive Testing for the ESS accelerator
The ESS linac is under construction by the ESS partner institutes (socalled In-Kind Contributors - IKC) and will operate the most powerful proton beam ever for neutron spallation source. The linac delivers 5 MW via 2 GeV protons at a repetition rate of 14 Hz at the He-cooled solid tungsten target. The pulsed neutrons, result of the spallation, will reach the science instruments after having been m
Blood biomarkers of brain injury for outcome prediction after cardiac arrest
Accounting for the Scarcity of Time as Patients Approach End of Life: The Construction of End-Weighted Time Toxicity
ObjectivesPeople with serious illness approaching end of life often end up in emergency and hospital care, frequently against expressed preferences. Consequently, oncology trials record care days as a measure of treatment burden called “time toxicity.” However, this measure ignores the diminishing marginal utility of time: that the value of a day is higher when fewer remain. We aimed to incorporat
Plant conservation hologenomics : integrating population genomics with mycobiome assessments for protected orchid species
Growing evidence of the microbiome's importance for plant ecology highlights the need for conservation strategies that consider both plants and their microbial partners, the holobiont. Population genomics are valuable tools for designing conservation strategies but rarely accounts for host- or site-specific microbial interactions. Orchids, with their dependence on specific mycorrhizal fungi, exemp
A Data Driven Approach for Resolving Time-dependent Differential Equations with Noise
We propose data-driven surrogate models to solve systems of time-dependent differential equations coupled with noise. Using a feedforward neural network, we separately learn the noise and solution, tackling approximations across regimes with bifurcations and rare events. Focusing on irregular data generated by a stochastic noise model on a one-dimensional spatial lattice coupled to a differential
Emelies personliga resa – transkriberad version av podd
I det här avsnittet berättar Emilie om hur det är att studera på universitetet när man inte ser och tar sig fram med rullstol. Emelie berättar också om sin väg till universitetsstudier, farhågor och förväntningar. Hon tar också upp utmaningar på vägen och vilket stöd och anpassningar som har behövts för att göra studierna tillgängliga. I avsnittet pratar vi också om små saker som har stor betydels
Linguistic correlates to communicative proficiency levels of the CEFR:The case of syntactic complexity in L2 English and L3 French
Musculoskeletal pain rehabilitation A one-year follow-up of occupational performance, psychosocial functioning and disability
Popular Abstract in Swedish Interdisciplinära smärtrehabiliteringsprogram har visat bättre resultat än mindre intensiva åtgärder. Det saknas dock kunskap inom flera olika områden. Denna avhandling har bland annat fokuserat vilka aktivitetsproblem som personer som genomgått ett sådant program upplever viktigast att förbättra. Alla deltagarna i programmet hade långvarig muskuloskeltal smärta med komMultidisciplinary pain rehabilitation programmes are found decreasing pain and improve back-to-work rates. There is, however, a lack of knowledge in several respects. The overall aim of this thesis was to study outcomes in terms of occupational performance, satisfaction with performance, psychosocial functioning, disability, and coping profiles at a one-year follow-up after a musculoskeletal pain
Muscle function and physical activity in pre-pubertal school children
Popular Abstract in Swedish Bakgrund: Regelbunden fysisk aktivitet och träning anses som en livsstilsfaktor som kan förbättra muskelstyrkan, skelettet, konditionen och kroppssammansättningen. För barn och ungdomar är fysisk aktivitet inte bara viktigt för att träna de muskulära funktionerna, koordinationen och balansen. I ett större perspektiv kan en fysiskt aktiv livsstil också minska risken för Background: Regular participation in physical activity or organized exercise is regarded as one important lifestyle factor that could improve musculoskeletal health, fitness and body composition. For children and adolescents physical activity is important not only in training of the neuromuscular system, coordination and balance, but in a wider perspective, for adopting a lifestyle that possibly r
One Step Forward and One Step Back. State regulation of environment and sustainable development through the use of the Education Act, school curricula and syllabuses (1990-2010)
The aim of this sociology of law-orientated article is to analyse and describe legislative and regulatory processes concerning the task given to schools focusing on environment and sustainable development. We are describing the policy-making processes in this field from 1990 to 2011. The study involves key interviews and content analysis of national policy documents as well as legal sources, in or
A Way to Estimate and Correct for Fractal Dimension of Hygroscopic Growth Data
Why the mirror is a sign — and why the television picture is no mirror. Two episodes in the critique of the iconicity critique
In his recent work, Eco abandons his conventionalist theory of pictures, which was heavily censored by, among others, the present author. In so doing, however, Eco now goes to the other extreme, claiming that television images are like mirrors, which are no signs. It is my contention that Eco fails to come up with a more acceptable theory of iconicity. Since Eco is one of the few semioticians conc
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Reflection/Transmission Study of Two Fabrics with Microwave Properties
In this study, the transmission and reflection of two conductive fabrics are investigated in the frequency range from 2 to 18 GHz. One of the fabrics is a non-woven polypyrrole and the other consists of a polyethylene warp with steel threads in the weft. Reflection and transmission measurements are performed in order to characterize the electromagnetic properties of the materials. Reflection measu
Improved xylose and arabinose utilization by an industrial recombinant Saccharomyces cerevisiae strain using evolutionary engineering
BACKGROUND: Cost-effective fermentation of lignocellulosic hydrolysate to ethanol by Saccharomyces cerevisiae requires efficient mixed sugar utilization. Notably, the rate and yield of xylose and arabinose co-fermentation to ethanol must be enhanced. RESULTS: Evolutionary engineering was used to improve the simultaneous conversion of xylose and arabinose to ethanol in a recombinant industrial Sacc
Conditions for the convergence in distribution of stationary normal processes
The asymptotic distribution of the maximum Mn=max1=
Integrated selective enrichment target (ISET) - A generic microfabricated sample preparation device
A combined sample preparation and sample presentation device, Integrated Selective Enrichment Target (ISET), consisting of an array with 96 perforated nanovials is described. Each perforated nanovial can be filled with soild-phase extraction media for purification and concentration of biomolecules prior to mass spectrometry. The ISET platform provides an efficient, economic and generic sample trea
PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression.
Accelerated cell aging, indexed in peripheral leukocytes by telomere shortness and in peripheral blood mononuclear cells (PBMCs) by telomerase activity, has been reported in several studies of major depressive disorder (MDD). However, the relevance of these peripheral measures for brain indices that are presumably more directly related to MDD pathophysiology is unknown. In this study, we explored
The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation.
Germ layer formation and primary axis development rely on Fibroblast growth factors (FGFs). In Xenopus, the secreted serine protease HtrA1 induces mesoderm and posterior trunk/tail structures by facilitating the spread of FGF signals. Here, we show that the serpin Protease nexin-1 (PN1) is transcriptionally activated by FGF signals, suppresses mesoderm and promotes head development in mRNA-injecte
