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Spondyloarthritis (SpA) is an umbrella term describing a family of chronic inflammatory rheumatic diseases. These diseases are characterised by inflammation of the axial skeleton, peripheral joints, and entheseal insertion sites throughout the body which can lead to structural joint damage including formation of axial syndesmophytes and peripheral osteophytes. Genetic evidence, preclinical and cli
The production of blood cells is regulated by the action of external factors, cytokines, that can be released by many cell types. In the first place, a population of multipotent stem cells, mostly in the resting Go phase of the cell cycle, but with self-renewal capacity, gives rise to progenitor cells that are predetermined for differentiation into all kinds of blood cells. Expression of genes for
This article presents a shared vision among stakeholders across the value chain on the use of radio positioning and sensing for road safety in the 5G ecosystem. The key enabling technologies and architectural functionalities are explored, focusing on the extremely stringent localization and communication requirements. A case study for joint radar and communication using experimental data showcases
Low-Power Wide-Area Networks operating in the unlicensed bands are being deployed to connect a rapidly growing number of Internet-of-Things devices. While the unlicensed sub-GHz band offers favorable propagation for long-range connections, measurements show that the energy consumption of the nodes is still mostly dominated by the wireless transmission affecting their autonomy. We investigate the p
Conditions experienced early in development can affect the future performance of individuals and populations. Demographic theories predict persistent population impacts of past resources, but few studies have experimentally tested such carry-over effects across generations or cohorts. We used bumble bees to test whether resource timing had persistent effects on within-colony dynamics over sequenti
Riktlinjer för Kungl. Konsthögskolans grafiska formgivning beskrivs i skriften Mellan sköldebrev och varumärkesmanual. Skriften är främst riktad till dig som arbetar med högskolans grafiska formgivning och kommunikation, men även till dig som har annan anknytning till verksamheten eller är intresserad av konstnärliga högskolors kommunikation med omvärlden.
This study investigates photomultiplier tube (PMT) nonlinearities, relevant for lifetime phosphor thermometry, at various decay times to assess and minimize the impact on temperature measurement accuracy. The focus is single-shot measurements performed in harsh environments where phosphor signal attenuation often is a concern. The sensitivity of decay time measurements to changing phosphorescence
Today, it is common knowledge in the cyber-physical systems domain that the tight interaction between the cyber and physical elements provides the possibility of substantially improving the performance of these systems that is otherwise impossible. On the downside, however, this tight interaction with cyber elements makes it easier for an adversary to compromise the safety of the system. This beco
Real-time communication over Ethernet is becoming important in various application areas of cyber-physical systems such as industrial automation and control, avionics, and automotive networking. Since such applications are typically time critical, Ethernet technology has been enhanced to support time-driven communication through the IEEE 802.1 TSN standards. The performance and stability of contro
We construct families, and concrete examples, of simple extensions of the Standard Model that can yield ultralight real or complex vectors or scalars with potential astrophysical relevance. Specifically, the mass range for these putative fundamental bosons (∼ 10-10-10-20 eV) would lead dynamically to both new non-black hole compact objects (bosonic stars) and new non-Kerr black holes, with masses
Objective: Fenestrated endovascular aortic aneurysm repair (FEVAR) for juxtarenal aortic aneurysm (jAAA) disease is safe and effective with good short- and mid-term outcomes. The durability issues have mainly focused on the proximal and distal seal and target vessel (TV) instability, and long-term data are scarce. In previous studies, we have reported the short-term outcomes after FEVAR and compar
Why, in the midst of the global Coronavirus pandemic, do so many people seem resistant to the recommendations of established medical experts? In this chapter, I explore possible structural causes of this resistance in the U.S. context. I argue that in the “post-truth” era, attempts to encourage people to wear face masks and get vaccinated confront challenges pertaining to how scientific knowledge
In this work, combustion and thermal decomposition processes were studied employing laser-based diagnostic techniques, and the techniques were improved and demonstrated to achieve enhanced detection sensitivity. Raman spectroscopy was employed to study flames under elevated and atmospheric pressures with various fuels, such as methane, hydrogen-enriched methane, DME, ethylene, and ammonia. Raman s
Radiopharmaceuticals have been used for the treatment of various forms of cancer since the 1940s. In recent years, the advantages of alpha emitting radionuclides have emerged as a favourable treatment option. However, most alpha emitting radionuclides have long decay chains with long-lived daughter radionuclides. This leads to uncertainties in the dosimetry for normal organs and tissues, when esta
ACN-Sim is a data-driven, open-source simulation environment designed to accelerate research in the field of smart electric vehicle (EV) charging. It fills the need in this community for a widely available, realistic simulation environment in which researchers can evaluate algorithms and test assumptions. ACN-Sim provides a modular, extensible architecture, which models the complexity of real char
The opportunistic pathogen Pseudomonas aeruginosa, a major cause of nosocomial infections, uses carbohydrate-binding proteins (lectins) as part of its binding to host cells. The fucose-binding lectin, LecB, displays a unique carbohydrate-binding site that incorporates two closely located calcium ions bridging between the ligand and protein, providing specificity and unusually high affinity. Here,
Ammonia (NH3) is a sustainable fuel with excellent emission characteristics. Hence, it is important to develop diagnostic techniques for NH3 combustion. In this paper, femtosecond laser-induced plasma spectroscopy (FLIPS) was performed in premixed NH3∕air flames. The plasma emission spectra induced by the femtosecond laser in the flame and the chemiluminescence spectra of the flame itself were bot
