Filetype
Background and purpose — During the last decades, treatment of distal radius fractures (DRFs) has changed, with surgical intervention being more common and with new techniques. We investigated whether this change has influenced the subjective outcome. Here we report, year by year, the 1-year score after a DRF over a 10-year-period, using a patient-reported outcome measure. Patients and methods — P
Rationale: Mechanisms underlying vasomotor abnormalities and increased peripheral resistance exacerbating heart failure (HF) are poorly understood. Objective: To explore the role and molecular basis of myogenic responses in HF. Methods and Results: 10 weeks old C57Bl6 mice underwent experimental myocardial infarction (MI) or sham surgery. At 1 to 12 weeks postoperative, mice underwent hemodynamic
This report concerns element strength and stiffness of cross laminated timber (CLT) at in-plane beam loading and includes presentation of experimental investigations and a review of some analytical models for structural analysis. A total of 20 individual tests were carried out, divided into five different test series which each comprise four nominally equal tests. The test series include prismatic
BACKGROUND Although evidence suggests that some occupations may be a risk factor for small-for-gestational age (SGA) birth, associations between a wide range of maternal and paternal occupations and risk of SGA births remain unclear. Our objective was to analyze the risk of SGA births by parental occupation, including the entire Swedish population of mothers (>/=20 years) and fathers. METHODS We l
The purpose of this dissertation is to evaluate the effectiveness and cost-effectiveness of Multisystemic Therapy (MST) in Sweden. This evaluation is set against the background of evidence-based social work practice and is organized around four separate but interrelated studies. The first of these studies used program theory reconstruction to investigate three conceptualizations of evidence-based
Objective. To examine psychiatric patients' experience of mechanical restraints and to describe the care the patients received. Background. All around the world, threats and violence perpetrated by patients in psychiatric emergency inpatient units are quite common and are a prevalent factor concerning the application of mechanical restraints, although psychiatric patients' experiences of mechanica
OBJECTIVE. We re-evaluated a cohort of patients referred for reflux symptoms and objectively diagnosed with pathological reflux, with the purpose of clarifying the course of conservatively treated gastroesophageal reflux disease (GERD). MATERIAL AND METHODS. All consecutive patients with GERD diagnosed between 1984 and 1988 showing pathologic 24-h pH-metry in the interval 3.8-10% and without any p
The severity of urinary tract infection (UTI) reflects the quality and magnitude of the host response. While strong local and systemic innate immune activation occurs in patients with acute pyelonephritis, the response to asymptomatic bacteriuria (ABU) is low. The immune response repertoire in ABU has not been characterized, due to the inherent problem to distinguish bacterial differences from hos
Subcellular localization of protein kinase often plays an important role in determining its activity and specificity. Protein kinase C (PKC), a family of multi-gene protein kinases has long been known to be translocated to the particular cellular compartments in response to DAG or its analog phorbol esters. We used C-terminal green fluorescent protein (GFP) fusion proteins of PKC isoforms to visua
Protein stability assessment of seven model proteins in the presence of low molecular weight polyethyleneimine (PEI, MW 2000 Da) was performed. Thermodynamic stability, monitored by circular dichroism (CD) spectroscopy, showed that the polymer did not have a major effect on the melting temperature (T-m) of the basic proteins - muscle lactate dehydrogenase (LDH), ribonuclease A, lysozyme and cutina
BACKGROUND: Antibody-drug conjugates, comprising monoclonal antibodies (MoAbs) that bind to tumor-associated antigens, display different toxicity profiles compared with radiolabeled MoAbs. Dose-limiting toxicities may include damage to the liver and myelotoxicity. The drug component is the antimitotic agent auristatin, which is 1001000 times more potent than doxorubicin. Consequently, auristatin a
Background For previously untreated children with severe hemophilia A, it is unclear whether the type of factor VIII product administered and switching among products are associated with the development of clinically relevant inhibitory antibodies (inhibitor development). Methods We evaluated 574 consecutive patients with severe hemophilia A (factor VIII activity, <0.01 IU per milliliter) who were
This master thesis investigates material characterization by reflection and transmission of electromagnetic waves in the 40-60 GHz band (millimeter-wave spectrum) for different materials. The free-space measurement method is a fast, efficient and non-destructive way of examining a material and is being researched by both academics and industries. The theory of how electromagnetic waves interact w
Fastighetsbolag på den svenska aktiemarknaden har under en lång tid varit mycket lönsamma och en god investering för aktieinvesterare. Syftet med denna undersökning är att avgöra och definiera vilka strategier svenska börsnoterade fastighetsbolag använder sig av, samt hur dessa val av strategier påverkar ett fastighetsbolags värdeutveckling på börsen. Ytterligare skall undersökningen ta reda på huProperty management companies on the Swedish stock market have long been very profitable and represented a good investment for shareholders. The purpose of this study is to determine and define the property-related strategies of listed Swedish property management companies – and how the choice of strategies affects the company's performance on the stock market. Furthermore, the analysis aims t
Fram till 2009 kunde domstolen vid brottet mord döma till tio års fängelse eller till livstids fängelse. 2009 ändrades straffskalan och möjliggjorde att domstolen kunde döma ut ett tidsbegränsat straff på lägst tio år och högst arton år. I NJA 2013 s. 376 uttalade HD att utgångspunkten för ett mord utan förmildrande eller försvårande omständigheter skulle vara fängelse i fjorton år. Redan året eftUntil 2009 the punishment for murder was ten years or life imprisonment. In 2009 there was an amendment of the law, which expanded the area where the court could convict someone to a fixed sentence; ten years as the lowest and eighteen years a maximum. In NJA 2013 p. 376 the Supreme Court ruled that the basic assumption for a murder without aggravating- or extenuating circumstances was a fourteen
Research on financial crises is important and especially relevant nowadays when the economy is slowing down globally. The crisis 2007-8 and the Great Depression of the 20th century are the longest and most severe financial calamities ever experienced and they share some eerie similarities with the Panic of 1857 – they all originate in the US but have international implications because they take pl
