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This paper investigates the impact of scientific relatedness on knowledge dynamics in biotech at the city level during the period 1989-2008. We assess the extent to which the emergence of new research topics and the disappearance of existing topics in cities are dependent on their degree of scientific relatedness with existing topics in those cities. We make use of the rise and fall of title words
We present here a study of the adsorption of 2-butyne (CH3-C equivalent to C-CH3) on the Si(0 01)-2 x 1 silicon surface at room temperature using synchrotron radiation photoemission spectroscopy (XPS) and X-ray absorption spectroscopy (NEXAFS). In particular, the Si2p and C1s core levels were followed by real-time photoemission (measuring while dosing). The intensity of the Si2p surface state comp
Background. For Diffuse large B-cell lymphoma (DLBCL), the International Prognostic Index is the major tool for prognostication and considers an age above 60 years as a risk factor. However, there are several indications that increasing age is associated with more biological complexity, resulting in differences in DLBCL biology depending on age. Methods. We conducted a registry-based retrospective
Popular Abstract in Swedish Förmågan hos levande vävnader att läka skador är en basal faktor för överlevnad och utgör grundförutsättningen för all kirurgisk verksamhet. Det finns lokala skillnader beträffande celltyper och tidsförlopp, men mycket talar för att sårläkningsprocessen är principiellt likartad i alla vävnader. Sårläkning indelas i olika faser, varav den första utgöres av en inflammatorWound healing is a multistep process with an initial inflammatory response, followed by synthesis of extracellular matrix components and finalized by a repair phase. One main goal was to determine the impact and adhesive mechanisms of neutrophil recruitment in anastomotic healing in the colon. Passive immunization against CD18 abolished anastomotic accumulation of neutrophils, whereas no effect on
Popular Abstract in Swedish I avhandlingen presenteras resultaten från studier av EGF-moduler från blodkoagulationsproteiner. Dessa studier har utförts med högupplösande kärnmagnetisk resonansspektroskopi. Resultaten av studierna återges i denna populärvetenskapliga sammanfattning. Som bakgrund ges inledningsvis en introduktion till den grundläggande biologin och den teknik som använts i studiernaModules are independently folding protein domains defined on the gene level. The epidermal growth factor-like (EGF) modules are involved in protein-protein interactions and are found in numerous membrane proteins and extracellular proteins, including many proteins of the blood coagulation system. A subset of the EGF modules binds one Ca2+ with an affinity that is often influenced by the
This chapter reassesses the modernization processes at work in Republican China during the Warlord period between 1911 and 1927 by focusing on corporate, public action by non-state interest groups and organizations. In particular, it looks at modes of corporate governing at the interface of business/economy and education: the realm of vocational education. The chapter examines a particularly illum
Popular Abstract in Swedish Spatiell struktur hos Corylus avellana (Betulaceae), hassel, med avseende på genetisk och morfometrisk variation Hassel, (Corylus avellana) är en vindpollinerad perenn buske som förekommer i mer eller mindre sammanhängande bestånd i stora delar av Europa. I denna avhandling har jag undersökt den genetiska och morfometriska variationen på olika hierarkiska nivåer hos haIn the present thesis, I investigated the spatial structure of genetic and morphometric variation in the widespread wind-pollinated shrub Corylus avellana (L.) Betulaceae, hazel, and related the variation to geographic distribution and different spatial scales. The plant material derived from natural populations in Europe, with special emphasis on the Baltic island of Öland, Sweden. Genetic and mo
This dissertation has three cornerstones: * Haptics * Human-Computer Interaction (HCI) * Blind Users Haptics deals with controlling human movements and getting feedback through the sense of touch. A haptic interface transmits forces to a person’s hand or fingers in a way that mimics the sensation of touching real objects. Virtual haptic touch can be particularly useful for people with visual i
Background Recanalization of arterial duct (AD) is rarely needed. Objective The aim of this study is to report our experience regarding the feasibility and effectiveness of arterial duct recanalization in three infants and review the relevant literature. Methods and results We report on three patients with decreased pulmonary blood flow after initial palliation. The first patient had pulmonary atr
The contiguity and phase of sequence information are intrinsic to obtain complete understanding of the genome and its relationship to phenotype. We report the fabrication and application of a novel nanochannel design that folds megabase lengths of genomic DNA into a systematic back-and-forth meandering path. Such meandering nanochannels enabled us to visualize the complete 5.7 Mbp (1mm) stained DN
Popular Abstract in Swedish Varje dag producerar vår kropp många miljarder nya blodceller. Dessa celler är livsnödvändiga för att många funktioner i kropp ska fungera. Exempelvis hjälper de till med att skydda oss från sjukdomar, läka skador, och med att transportera syre och avfallsämnen. Blodsystemet (det hematopoetiska systemet) är uppbyggt som en hierarki där hematopoetiska stamceller finns påIn the blood system, knowledge on the regulation of hematopoietic stem cells (HSCs) and their immature progeny has provided roadmaps of differentiation. Such information can also have a value to understand the etiology of hematological cancers, since clinical heterogeneity and prognostic therapeutic outcomes have been proposed to associate with the specific developmental stage from which the trans
This article aims to share experience from a Swedish project on the introduction and implementation of Open Educational Resources (OER) in higher education with both national and international perspectives. The project, OER – resources for learning, was part of the National Library of Sweden Open Access initiative and aimed at exploring, raising awareness of and disseminating the use of OER and th
Haploid hybrid gametophytes are often present at low frequencies in sympatric populations of Sphagnum capillifolium and Sphagnum quinquefarium. We used intersimple sequence repeat (ISSR) markers and polymerase chain reaction-restriction fragment length polymorphism of the trnL(UAA) intron of the chloroplast genome to reveal the nuclear and chloroplast composition of mature hybrid gametophytes from
In plant respiratory chains, alternative pathways for NAD(P)H oxidation are mediated by type II NAD(P)H dehydrogenases belonging to the NDA, NDB, and NDC families. For the latter type, Arabidopsis thaliana contains a single gene, NDC1, whose functional role has not previously been analyzed in the plant. We found that A. thaliana NDC1 is alternatively spliced. Four base pairs at the 3' end of intro
In insects, the surface area of the compound eye increases with body size both within and between species with only a slight negative allometry. This increase in surface area permits changes in eye structure that affect the eye's acuity and sensitivity, two features of eye performance that cannot be simultaneously maximized. Hence, as eye size varies within a lineage, so will the compromises betwe
The present study was designed to delineate the presence of COMP at the ultrastructural level comparing concentrations between two areas of articular cartilage from the equine third carpal bone, subjected to different loading, from trained and untrained horses. We also analyzed the fibril thickness of collagen type II in the same compartments and zones. Samples were collected from high load-bearin
Skin fibrosis is characterized by activated fibroblasts and an altered architecture of the extracellular matrix. Excessive deposition of extracellular matrix proteins and altered cytokine levels in the dermal collagen matrix are common to several pathological situations such as localized scleroderma and systemic sclerosis, keloids, dermatosclerosis associated with venous ulcers and the fibroprolif
An exploratory study of a train evacuation inside a tunnel was performed in order to study the effects of different train exit configurations on the flow rate of people through the exit. A total of 84 participants in the ages 18–40 years took part in the experiment, which was carried out on two separate days and involved 18 evacuation scenarios. The statistical analysis of the experiment demonstra
Amendments to Articles 3.3 and 3.4 of the Kyoto Protocol have meant that detection of vegetation change may now form an interracial part of national soil carbon stocks. In this study multispectral multi-platform satellite data was processed to detect change to the surface vegetation of four peatland sites and one heath in Ireland. Spectral and spatial thresholds were used on difference images betw
Surfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view of its bioactive properties which are in relation with its ability to interact with lipids of biological membranes. In this work, we investigated the effect of surfactin on membrane structure using model of membranes, vesicles as well as supported bilayers, presenting coexistence of fluid-disordered (DOPC)
