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HMGA2 and MDM2 expression in lipomatous tumors with partial, low-level amplification of sequences from the long arm of chromosome 12.

Ordinary lipomas are cytogenetically characterized primarily by simple balanced chromosome aberrations with stable morphologies, most of which affect chromosome segment, 12q13-15, where the HMGA2 gene plays a key pathogenetic role. Atypical lipomatous tumors (ALTs) display supernumerary ring or giant marker chromosomes with amplification of several genes including HMGA2 and MDM2. A study of HMGA2

Parametric quantification of myocardial ischaemia using real-time perfusion adenosine stress echocardiography images, with SPECT as reference method.

Summary Background: Real-time perfusion (RTP) adenosine stress echocardiography (ASE) can be used to visually evaluate myocardial ischaemia. The RTP power modulation technique, provides images for off-line parametric perfusion quantification using Qontrast((R)) software. From replenishment curves, this generates parametric images of peak signal intensity (A), myocardial blood flow velocity (beta)

WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells

An important role for WNT-5A is implicated in a variety of tumors, including breast carcinoma. We previously showed that WNT-5A signaling inhibits migration and metastasis of breast cancer cells, and that patients with primary breast cancer in which WNT-5A was expressed have a better prognosis. Despite the fact that RhoGTPase Cdc42 is commonly associated with increased cell migration, we here show

Test-Retest Reliability and Convergent Validity of Three Manual Dexterity Measures in Persons With Chronic Stroke

BACKGROUND: Decreased manual dexterity is common in persons after stroke. Different measures are used to assess manual dexterity, but a lack of knowledge exists about their reliability and how they are related.OBJECTIVE: To evaluate the test-retest reliability and convergent validity of 3 manual dexterity measures after stroke.DESIGN: A test-retest design.SETTING: University Hospital.PARTICIPANTS:

From ad-man to digital manager. How strategic communication became a professional project

n this paper I argue that strategic communication practitioners are set to form a monopoly over specific skills and competences, which separate them from other groups in order to gain professional status. This process has developed gradually; requirements for communication workers were not that high put a couple of decades ago. But in relation to demands on a societal level, strategic communicatio

Performance predictions of laminar and turbulent heat transfer and fluid flow of heat exchangers having large tube-diameter and large tube-row by artificial neural networks

In this work an artificial neural network (ANN) is used to correlate experimentally determined and numerically computed Nusselt numbers and friction factors of three kinds of fin-and-tube heat exchangers having plain fins, slit fins and fins with longitudinal delta-winglet vortex generators with large tube-diameter and large the number of tube rows. First the experimental data for training the net

Joint space width of the tibiofemoral and of the patellofemoral joint in chronic knee pain with or without radiographic osteoarthritis: a 2-year follow-up

Objectives: To assess the interval change of the minimal joint space width (MJS) in radiographs of the tibiofemoral (TF) joint and of the patellofemoral (PF) joint with a 2-year follow-up in middle-aged people with longstanding knee pain with or without radiographic osteoarthritis (OA) and to study the precision of the MJS measurements. Design: In the format of a prospective study of early OA the

Population-wide incidence estimates for soft tissue knee injuries presenting to healthcare in southern Sweden: data from the Skane Healthcare Register

Introduction: Soft tissue knee injury is a well-established and potent risk factor for development of knee osteoarthritis. However, there is a paucity of epidemiological data from the general population. Our aim was to estimate the annual person-level incidence for a wide spectrum of clinically diagnosed soft tissue knee injuries, and their distribution by age, sex, and season. Methods: In Sweden,

FAKTA magnetkamera – Vetenskap och Hälsa

FAKTA magnetkamera – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök FAKTA magnetkamera 2015-06-08 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. MR (magnetisk resonanstomografi) Med MR kan man ta tvärsnittsbilder av kroppens organ. Tekniken utnyttjar att vi

https://www.vetenskaphalsa.se/fakta-magnetkamera/ - 2026-05-17

Homologous recombination deficiency in primary ER-positive and HER2-negative breast cancer

BACKGROUND: Homologous recombination deficiency (HRD) originating from inactivation of genes like BRCA1/BRCA2 is a targetable abnormality common in triple-negative breast cancer (TNBC). In estrogen-receptor (ER)-positive HER2-negative (ERpHER2n) breast cancer (BC), HRD prevalence and clinical impact are unclear.METHODS: We analyzed 502 ERpHER2n tumors from patients recruited via the population-rep

Effect of fertilization and growth conditions on woody-tree biomass composition

A biorefinery can operate with various plant materials as feed stock, (in contrast to fossil-based oil refineries). It has been defined by the International Energy Agency, Task 42, as “the sustainable processing of biomass into a spectrum of marketable bio-based products (chemicals, materials) and bioenergy (biofuels, power, heat)”. One of the challenges in operating large-scale facilities is that

SPIRIT-Children and Adolescents (SPIRIT-C) 2026 extension statement : enhancing the reporting and usefulness of paediatric randomised trial protocols

Randomised controlled trial (RCT) protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety. However, key information is often omitted from paediatric RCT protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmenta

SPIRIT-Children and Adolescents (SPIRIT-C) 2026 extension statement: enhancing the reporting and usefulness of paediatric randomised trial protocols

Randomised controlled trial (RCT) protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety. However, key information is often omitted from paediatric RCT protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmenta

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Objectives: Sjögren's disease (SjD) and systemic lupus erythematosus (SLE) share genetic risk at the DDX6-CXCR5 locus (11q23.3). Identifying and functionally characterising shared SNPs spanning this locus can provide new insights into common genetic mechanisms of autoimmunity. Methods: Transdisease meta-analyses, fine-mapping, and bioinformatic analyses prioritised shared likely functional single

Parallel Endografting And Chimney Endovascular (PEACE) registry outcomes in emergency repair of complex abdominal aortic aneurysms

Background: Chimney endovascular aneurysm repair (chEVAR) techniques have been described to manage a group of patients who are unsuitable for either open aortic aneurysm surgery or a variety of standard endovascular repair techniques. The aim of this study was to assess the long-term clinical outcomes of chEVAR in emergency settings for patients with abdominal aortic aneurysms that have complex mo

Bridging the gap in heart failure management : the effect of a cross-disciplinary intervention on guidelines-directed medical therapy in primary care

BACKGROUND AND AIMS: Guideline-directed medical therapy (GDMT) for heart failure (HF) is underutilized in primary care, particularly among older adults with chronic stable HF. This prospective quality improvement study, Heart Failure in Southern Sweden (HISS), evaluated the impact of a cross-disciplinary implementation project combining cardiology and primary care expertise to enhance GDMT adheren

Improved survival for women with stage i breast cancer in south-east Sweden : A comparison between two time periods before and after increased use of adjuvant systemic therapy

Purpose. Continuous minor steps of improvement in the management of breast cancer have resulted in decreased mortality rates during the last decades. The aim of this study was to compare the clinical outcome of patients with stage I breast cancer diagnosed during two time periods that differed with respect to adjuvant systemic therapy. Material and methods. The studied population consisted of all

Estimating the lake storage capacity on the Tibetan Plateau using satellite altimetry and imagery data : a comparative analysis of water volume change methods

Compared to lake area and water level, lake storage capacity more intuitively reflects regional climate changes. In this study, we first derived lakebed elevation profiles for individual ICESat-2 tracks based on the underwater stratification of laser photons, then integrating all valid elevation tracks within the water body to interpolate the bathymetry. On this basis, we calculated the capacity a

Structure and Function of Odorant Binding Proteins and Chemosensory Proteins in Moths.

Odorant Binding Proteins (OBPs) and Chemosensory Proteins (CSPs) are small soluble proteins found in the lymph of insect sensillae located on insect antennae. Odorant Binding proteins are implied in olfaction, by binding hydrophobic odorant molecules and transporting them to the olfactory receptor located on the dendrite of the olfactory neurons. They are divided into three groups, Pheromone Bindi

Medieföretagen PS Akademikerförbundet 6597 2012

Medieföretagen PS Akademikerförbundet 6597 2012 AKADEMIKERAVTALET Löner och allmänna anställningsvillkor Public Serviceföretag 2020–2023 Giltighetstid: 2020-11-01–2023-03-31 Tnr: 7 I Akademikerförbunden ingår: Akademikerförbundet SSR, Civilekonomerna, DIK, Sveriges Arbetsterapeuter, Jusek, Fysioterapeuterna, Naturvetarna, Sveriges Skolledarförbund, Sveriges Ingenjörer, Sveriges Psykologförbund, Sv

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/akademikerforbunden-aht/dokument/kollektivavtal/almega-medieforetagen-public-service_kollektivvtal_-2020-2023.pdf - 2026-05-17