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The use of a Peer Assisted Study Scheme to help the transition from Secondary school to Higher Education

This presentation will give an overview of a peer learning model called Supplemental Instruction - Peer Assisted Study Scheme (SI-PASS). SI-PASS was invented at the University of Missouri in Kansas City, USA in the early1970s and was then directed to Universities and for the university students. In this presentation, the focus and discussion will be on how SI-PASS can be implemented in secondary s

Implementation of Endoscopic Submucosal Dissection in a Western Institution

Endoscopic resection of colorectal polyps reduce morbidity and mortality from colorectal cancer (CRC).Endoscopic submucosal dissection (ESD) is a highly efficient and established method for treating advanced colorectal lesions in Asia, but experience of ESD in Western countries is limited. Large non-pedunculated colorectal lesions are prone to malignant transformation and it is therefore important

Studies of Thai blood group and platelet polymorphism. Implications for malaria susceptibility.

The objectives of the thesis were to seek a better understanding of polymorphic RBC surface molecules in the Thai, and to investigate the role of certain blood groups in malarial invasion. MALDI-TOF MS was employed in Study I as an efficient method for genotyping to establish the common blood group and platelet antigen genotypes of 396 blood donors. Investigation of outliers identified variation a

Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children

HLA-DQA1 and -DQB1 are strongly associated with type 1 diabetes (T1D), and DQ8.1 and DQ2.5 are major risk haplotypes. Next-generation targeted sequencing of HLA-DQA1 and -DQB1 in Swedish newly diagnosed 1- to 18 year-old patients (n = 962) and control subjects (n = 636) was used to construct abbreviated DQ haplotypes, converted into amino acid (AA) residues, and assessed for their associations wit

Conformational Entropy and Protein Flexibility in Drug Design Studied by NMR Spectroscopy

Proteins are complex molecules, present in all of the vital functions of life. The function of a protein is regulated by interactions between protein and other molecules. Drug design in pharmaceutical science aims to regulate the function of a protein by the design of synthesized molecules that binds to a protein with high affinity. A change in protein flexibility upon ligand binding can provide s

Fifteen Years of Democracy Export in the Balkans: Who Did What to Whom?

Conference on Remembering Communism: Celebrating 15 years of Democracy, Thessaloniki, June 4-5, 2004 Fifteen Years of Democracy Export in the Balkans: Who Did What to Whom? by Steven Sampson Department of Social Anthropology Lund University Lund, Sweden Contact: Sampson@Get2net.Dk. This paper argues that we must analyze democracy assistance as a specific practice separate from democracy and dem

Linking agricultural policies to population trends of Swedish farmland birds in different agricultural regions

1. The widespread declines of farmland birds have generally been linked to agricultural intensification. We tested the hypotheses that (i) changes in agricultural policy, through its effects on agricultural intensification and (ii) regional differences in agricultural intensification affect temporal and spatial population trends of farmland birds in Sweden. 2. We analysed regional bird populat

Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells

In the current work, we compared the ability of 17 beta-estradiol (E-2) and the selective estrogen receptor modulators (SERMs), tamoxifen (Tam), raloxifene (Ral) and ospemifene (Osp) to promote the survival of osteoblast-derived cells against etoposide-incluced apoptosis. In order to compare the roles of the two estrogen receptor (ER) isotypes, we created a U2OS human osteosarcoma cell line stably

South-North and Radial Traverses through the Interplanetary Dust Cloud

Identical in situ dust detectors are flown on board the Galileo and Ulysses spacecraft. They record impacts of micrometeoroids in the ecliptic plane at heliocentric distances from 0.7 to 5.4 AU and in a plane almost perpendicular to the ecliptic from -79 deg to +79 deg ecliptic latitude. The combination of both Ulysses and Galileo measurements yields information about the radial and latitudinal di

The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure

Background: In CIBIS III, initiating chronic heart failure (CHF) treatment with bisoprolol (target dose 10 mg q.d.) followed by combination therapy with enalapril (target dose 10 mg b.i.d.), compared to the opposite order, showed similar effects on survival and hospitalization. By echocardiography, we evaluated the effects of these treatment strategies on cardiac structure and function. Methods: I

Chem2Side : A Deep Learning Model with Ensemble Augmentation (Conventional + Pix2Pix) for COVID-19 Drug Side-Effects Prediction from Chemical Images

Drug side effects (DSEs) or adverse drug reactions (ADRs) are a major concern in the healthcare industry, accounting for a significant number of annual deaths in Europe alone. Identifying and predicting DSEs early in the drug development process is crucial to mitigate their impact on public health and reduce the time and costs associated with drug development. Objective: In this study, our primary

Spinel group minerals in carbonaceous and ordinary chondrites

Populärvetenskaplig sammanfattning: Inflödet av kosmiskt material till jorden har inte varit konstant sedan jorden bildandes, men det är svårt att studera hur inflödet förändrats eftersom meteoriter lätt omvandlas och förstörs på jordytan. En metod för att studera förändringar i inflödet av kosmiskt material till jorden är att titta på förändringar i halten kromit i sediment. Kromit är ett mineralMeteorites are easily altered in the oxygen-rich environment on the Earth surface. Fossil meteorites are thus uncommon and in the ones, which are found, almost all minerals are secondary. However, the spinel group mineral chromite is resistant to alteration and has successfully been used as a proxy for ordinary chondrites in sediment. The frequency and composition range of spinel group minerals in

The mineral composition of the Burkland Cu-sulphide deposit at Zinkgruvan, Sweden : a supplementary study

Populärvetenskaplig sammanfattning: Det aktuella arbetet kompletterar Karolina Bjärnborgs masteruppsats från 2009 (Examensarbete Berggrundsgeologi Nr. 240) i samma ämne. Avsikten med arbetet är att testa och styrka hennes resultat med ytterligare prov och analyser. Syftet med båda projekten är att bestämma vilka malmmineral som finns och deras kemiska sammansättning i en kopparmineralisering i ZinThe Zinkgruvan Mining AB, situated in south-central Sweden in Örebro County, south-east of Åmmeberg, plans to expand their production on a massive, carbonate hosted copper-sulphide ore deposit, the Burkland Cu-mineralization in the eastern part of Knalla. At present mainly Zn-Pb-Ag are mined. The deformed Cu-mineralization belongs to the south-western Bergslagen ore province. It is of Paleoprotero

Nytt sätt att lagstifta om saklig grund

År 2022 genomfördes en omfattande reform av den svenska arbetsrätten, med fokus på bland annat att modernisera lag (1982:80) om anställningsskydd (LAS). Reformen utgick från januariavtalet 2019 där regeringen åtog sig att lägga fram lagstiftningsförslag som stämde överens med en eventuell partsöverenskommelse framtagen av arbetsmarknadens parter vilket resulterade i ett nytt Huvudavtal som blev grIn 2022, a major reform of Swedish labour law was implemented, with one of its key objectives being the modernisation of the Employment Protection Act (LAS). The reform originated from the 2019 January Agreement and granted certain labour market organisations an active and norm-setting role in the drafting of legislative proposals. The government committed to presenting legislative initiatives in

Cardiovascular disease and beta-cell function at diagnosis of serologically defined adult-onset type 1 and type 2 diabetes in two Swedish cohorts 15 years apart

OBJECTIVES: To describe the prevalence of cardiovascular disease (CVD) at the time of diagnosis of adult-onset type 1 (T1D) and type 2 (T2D) diabetes, in a recent cohort and compare to a previous cohort from the same region. Further, to explore factors influencing the prevalence of pre-existing CVD, including age, sex, body mass index (BMI) and C-peptide; in the later cohort also heart failure, hy

Titmice turn on the central heating

Small birds are hot creatures with an average body temperature of 40° Centigrade, and so must burn energy at a formidable rate to stay warm. This becomes quite the challenge in winter when birds are 40-50 degrees warmer than outside for extended periods, even in comparatively mild regions such as Scotland. Thus, the little bird in winter must spend most of the day either feeding or searching for f

Abundances of disk and bulge giants from high-resolution optical spectra : III. Sc, V, Cr, Mn, Co, Ni

Context. The formation and evolution of the Galactic bulge and the Milky Way is still a debated subject. Observations of the X-shaped bulge, cylindrical stellar motions, and the presumed existence of a fraction of young stars in the bulge have suggested that it formed through secular evolution of the disk and not through gas dissipation and/or mergers, as thought previously. Aims. Our goal was to

Effect of Ligand Modification on Properties of Iron-Tetracarbene Photosensitisers : Design, Synthesis and Photovoltaic Applications

The use of N-heterocyclic carbenes in conjunction with iron has been studied over the last decade for the purpose of achieving well-functioning iron-based photosensitisers. This is based on the strong σ- donating ability of the carbene, and the effect this has on the metal-based orbitals of iron, for achieving more stable excited states. This work has been done to harness this earth-abundant metal

Health in Negotiation : Cultural Analytical Perspectives on Health and Inequalities in the Swedish Asylum Context

Health inequalities are a persistent and growing issue in different countries worldwide. Sweden, despite being one of the scandinavian countries with internationally recognized welfare system is no exception. The issue of health disparities and its increase among some groups, including those who are categorised as migrant have been acknowledged. Emergence of the COVID-19 pandemic, however, reveale