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Nytt sätt att lagstifta om saklig grund

År 2022 genomfördes en omfattande reform av den svenska arbetsrätten, med fokus på bland annat att modernisera lag (1982:80) om anställningsskydd (LAS). Reformen utgick från januariavtalet 2019 där regeringen åtog sig att lägga fram lagstiftningsförslag som stämde överens med en eventuell partsöverenskommelse framtagen av arbetsmarknadens parter vilket resulterade i ett nytt Huvudavtal som blev grIn 2022, a major reform of Swedish labour law was implemented, with one of its key objectives being the modernisation of the Employment Protection Act (LAS). The reform originated from the 2019 January Agreement and granted certain labour market organisations an active and norm-setting role in the drafting of legislative proposals. The government committed to presenting legislative initiatives in

Cardiovascular disease and beta-cell function at diagnosis of serologically defined adult-onset type 1 and type 2 diabetes in two Swedish cohorts 15 years apart

OBJECTIVES: To describe the prevalence of cardiovascular disease (CVD) at the time of diagnosis of adult-onset type 1 (T1D) and type 2 (T2D) diabetes, in a recent cohort and compare to a previous cohort from the same region. Further, to explore factors influencing the prevalence of pre-existing CVD, including age, sex, body mass index (BMI) and C-peptide; in the later cohort also heart failure, hy

Titmice turn on the central heating

Small birds are hot creatures with an average body temperature of 40° Centigrade, and so must burn energy at a formidable rate to stay warm. This becomes quite the challenge in winter when birds are 40-50 degrees warmer than outside for extended periods, even in comparatively mild regions such as Scotland. Thus, the little bird in winter must spend most of the day either feeding or searching for f

Abundances of disk and bulge giants from high-resolution optical spectra : III. Sc, V, Cr, Mn, Co, Ni

Context. The formation and evolution of the Galactic bulge and the Milky Way is still a debated subject. Observations of the X-shaped bulge, cylindrical stellar motions, and the presumed existence of a fraction of young stars in the bulge have suggested that it formed through secular evolution of the disk and not through gas dissipation and/or mergers, as thought previously. Aims. Our goal was to

Effect of Ligand Modification on Properties of Iron-Tetracarbene Photosensitisers : Design, Synthesis and Photovoltaic Applications

The use of N-heterocyclic carbenes in conjunction with iron has been studied over the last decade for the purpose of achieving well-functioning iron-based photosensitisers. This is based on the strong σ- donating ability of the carbene, and the effect this has on the metal-based orbitals of iron, for achieving more stable excited states. This work has been done to harness this earth-abundant metal

Health in Negotiation : Cultural Analytical Perspectives on Health and Inequalities in the Swedish Asylum Context

Health inequalities are a persistent and growing issue in different countries worldwide. Sweden, despite being one of the scandinavian countries with internationally recognized welfare system is no exception. The issue of health disparities and its increase among some groups, including those who are categorised as migrant have been acknowledged. Emergence of the COVID-19 pandemic, however, reveale

Fungal cellulose decomposition : Insights into decomposition strategies using spectroscopic and molecular approaches

Cellulosa är den vanligaste biopolymeren på jorden och en viktig reservoar av organiskt kol i terrestra ekosystem. I skogar kommer mycket av denna cellulosa från trä och bryts ner av saprotrofa basidiomyceter. Dessa svampar klassificeras traditionellt som vitröta eller brunröta baserat på deras sönderfallsmekanismer i lignocellulosasubstrat. Huruvida dessa funktionella kategorier förblir distinktaCellulose is the most abundant biopolymer on Earth and a major reservoir of organic carbon in terrestrial ecosystems. In forests, much of this cellulose originates from wood and is decomposed by saprotrophic basidiomycetes. These fungi are traditionally classified as white rot or brown rot species based on their decay mechanisms in lignocellulosic substrates. Whether these functional categories re

Parental Well-being in Pediatric Oncology in Sweden - Nationwide Evidence from the Swedish Registers

Despite the average 5-year survival rate exceeding 85%, childhood cancer is still the most common cause of disease-related death among children in Sweden. A cancer diagnosis is profoundly traumatic not only for children themselves, but also for the entire family, particularly the primary caregivers, their parents. This project aimed to investigate the extent to which a childhood cancer diagnosis a

Interactions between β-haemolytic streptococci and the human host. Heart, skin and beyond.

Group C and G streptococci (GCS/GGS) and group A streptococci (GAS) belong to β-haemolytic streptococci (BHS). GCS/GGS can further be species determined to S. dysgalactiae, whereas S. pyogenes are GAS. S. dysgalactiae and S. pyogenes cause similar diseases, (e.g., skin and soft tissue infections, erysipelas, bacteraemia, and infective endocarditis (IE)). Erysipelas often presents as a sharply dema

Enabling Long-term Predictions and Cost-benefit Analysis Related to Housing Adaptation Needs for a Population Aging in Place : Protocol for a Simulation Study

Background: Policies that promote aging in place are common in Sweden and many other countries. However, the current housing stock cannot sufficiently accommodate a population aging in place considering how functional capacity and housing needs change as people age. To be suitable for all regardless of their functional ability, housing should be designed or adapted to facilitate the performance of

Assessment of maternal and child health care services performance in the context of COVID-19 pandemic in Addis Ababa, Ethiopia : evidence from routine service data

Background: In many settings, health care service provision has been modified to managing COVID-19 cases, and this has been affecting the provision of maternal and child health services. The aim of this study was to assess trends in selected maternal and child health services performance in the context of COVID-19 pandemic. Methods: A cross-sectional data review was conducted in Addis Ababa, Ethio

Role of Proneurotensin in Cardiometabolic Diseases

The burden of cardiometabolic diseases is increasing worldwide. Early detection of high-risk individuals is essential for appropriate diagnosis, better treatment outcomes, quality of life and lower health related costs. Aims: The overall aim of this thesis is to investigate the possible associations between plasma proneurotensin (Pro-NT) and risk of cardiovascular disease (CVD), type 2 diabetes (T

Polskans historia : En studie i melodityper och motivformer med utgångspunkt i Petter Dufvas notbok

The polska, under lots of different spellings and titles, was the dominant music and dance repertoire in Sweden for nearly 300 years. The main purpose of this thesis has been to clarify some of the principal characteristics in both its dance and music forms. The thesis has both a historical and an ethnomusicological perspective and moves in the intersection between different types of traditional m

Targeted spatial proteomic analysis of CD8+ T- and myeloid cells in tonsillar cancer

Background: Tonsillar cancer is caused by high-risk human papillomavirus (HPV), tobacco smoking, and alcohol abuse. Aspects of the patient’s immune response to this disease have arisen as prognostic factors and treatment targets, reflecting differences in the type and protein expression profile of immune cells. Because tonsillar cancers are heterogenous lesions such data need to be spatially resol

Ground-Based Hyperspectral Retrieval of Soil Arsenic Concentration in Pingtan Island, China

The optimal selection of characteristic bands and retrieval models for the hyperspectral retrieval of soil heavy metal concentrations poses a significant challenge. Additionally, satellite-based hyperspectral retrieval encounters several issues, including atmospheric effects, limitations in temporal and radiometric resolution, and data acquisition, among others. Given this, the retrieval performan

Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen : patient-level meta-analysis of randomised trials

BACKGROUND: As trials of 5 years of tamoxifen in early breast cancer mature, the relevance of hormone receptor measurements (and other patient characteristics) to long-term outcome can be assessed increasingly reliably. We report updated meta-analyses of the trials of 5 years of adjuvant tamoxifen.METHODS: We undertook a collaborative meta-analysis of individual patient data from 20 trials (n=21,4

Imbalance and fractures in the elderly Effects of decreased vibration sensation and vestibular asymmetry

Popular Abstract in Swedish Antalet fallolyckor och frakturer ökar ibland den äldre befolkningen och detta innebär en ökande social och ekonomisk belastning för samhället. En viktig orsak till fallolyckor kan vara dålig balans. Kontrollen av upprätt stående och gångförmåga baseras på komplexa processer av neuromuskulär aktivitet. Denna neuromuskulära aktivitet bygger på sensorisk information från

Translational and functional analyses of microRNAs in prostate cancer

Popular Abstract in Swedish Prostatacancer drabbar män över hela världen; i Sverige får ungefär 10 000 personer diagnosen varje år. För den enskilda individen kan följderna innebära fysiskt och psykiskt lidande, men även samhället belastas med höga vårdkostnader. För att undvika onödigt lidande, men också minska kostnaderna är det nödvändigt att ta fram nya läkemedel och metoder för att i god tid The aims of this thesis were to identify microRNAs (miRNAs) with prostate cancer prognostic and diagnostic potential, to discover miRNAs with therapeutic capacity against prostate cancer, and to investigate if prostate specific antigen (PSA) is miRNA regulated. Prostate cancer is a globally spread disease with low mortality, but some patients develop an aggressive lethal form of prostate cancer w

The molecular basis of thrombolysis and its clinical application in stroke

The rationale for thrombolysis, the most promising pharmacological approach in acute ischaemic stroke, is centred on the principal cause of most ischaemic strokes: the thrombus that occludes the cerebral artery, and renders part of the brain ischaemic. The occluding thrombus is bound together within fibrin. Fibrinolysis acts by activation of plasminogen to plasmin; plasmin splits fibrinogen and fi

Gestational Age at Birth and Mortality in Young Adulthood

Context Preterm birth is the leading cause of infant mortality in developed countries, but the association between gestational age at birth and mortality in adulthood remains unknown. Objective To examine the association between gestational age at birth and mortality in young adulthood. Design, Setting, and Participants National cohort study of 674 820 individuals born as singletons in Sweden in 1