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BACKGROUND: Preterm birth remains the major risk factor for the development of intraventricular hemorrhage, an injury that occurs in 25% of very low birth weight infants. Intraventricular hemorrhage is thought to be venous in origin and intrinsic thromboses in the germinal matrix are likely to play a triggering role. Antithrombin, a glycoprotein synthesized in the liver, is the major plasma inhibi
This volume provides an overview of applications of conceptual spaces theory, beginning with an introduction to the modeling tool that unifies the chapters. The first section explores issues of linguistic semantics, including speakers negotiation of meaning. Further sections address computational and ontological aspects of constructing conceptual spaces, while the final section looks at philosophi
This article applies a neo-documentalist approach to explore disciplinary information and knowledge making practices. The aim is to show how conceptions and materialities of what counts as documentation and documents are intertwined with changing and persisting disciplinary and sub-disciplinary practices of producing information and knowledge, of knowing, and informing. A collective, multivocal au
We have previously shown analytically that the biologically effective dose (BED), including effects of repair during irradiation and of incomplete repair between fractions, can be formulated using a convolution between the absorbed dose rate function and the function describing repair. In this work, a discrete formalism is derived along with its implementation via the fast Fourier transform. The i
L-DOPA is currently the standard treatment for alleviating the motor symptoms in Parkinson's disease. The therapeutic efficacy, however, diminishes as the disease progresses. It has been suggested that the beneficial effect of L-DOPA could be reestablished by changing the mode of administration. Indeed, continuous delivery of L-DOPA has been shown to be an effective way to circumvent many of the s
The utilization of biogas produced from organic materials such as agricultural wastes or manure is increasing. However, the raw biogas contains a large share of carbon dioxide which must be removed before utilization in many applications, for example, using the gas as vehicle fuel. The process – biogas upgrading – can be performed with several technologies: water scrubbing, organic solvent scrubbi
The Swedish Family-Cancer Database comprises a total of 11.8 million individuals covering the Swedish population of the past 100 years. Version VIII of the Database is described in the present article. Cancer cases were retrieved from the Swedish Cancer Registry for the period 1958-2006, including more than 1 million first primary cancers. The number of familial cancers in offspring is 14,000 when
We report the development of a new database of technology services and products for analysis of biobank samples in biomedical research. BARCdb, the Biobanking Analysis Resource Catalogue (http://www.barcdb.org), is a freely available web resource, listing expertise and molecular resource capabilities of research centres and biotechnology companies. The database is designed for researchers who requ
Introduction. Significant progress has been made in the understanding of physiological and pharmacological mechanisms of human sexual functioning through preclinical research in animal models. Aim. To provide an evidence-based documentation of the experimental models evaluating male and female sexual function for useful clinical translation. Methods. Consensus discussion over the past 18 months le
Universal perception and production constraints may constitute phonetic preconditions for historical sound change. It is pointed out that the traditional literature on the Swedish dialects provides a rich source of information in evaluating the diachronic role played by these constraints.
Modelling is a fairly mature technology that is already being adopted by industry. Unfortunately the tools for supporting Model-Driven Engineering are not at the same level of maturity. In particular merge tools that are an important help for collaboration lack a lot to be desired in providing the support that is needed on industrial projects. Current model merge tools and research approaches focu
The extension of businesses to incorporate the provision of function as a service in supplement to standalone products is an ongoing movement in manufacturing industry. In short, this means that the development intent should be guided by the need of ‘performance in use’ that the customer wants, e.g. thrust rather than an engine. By this, the established knowledge base challenges the development te
Specific advantages with Particle Induced X-Ray Emission are: its (1) multielemental capability, especially when combined with nuclear techniques for lighter elements, (2) speed, (3) low detection limits for small samples and (4) accuracy. To make full use of these advantages, analytical parameters have to be chosen optimally and the facility to be carefully designed. This paper describes an exper
