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Background: Halomonas boliviensis is a halophilic microorganism that accumulates poly(3-hydroxybutyrate) (PHB) using different carbons sources when nitrogen is depleted from the culture medium. This work presents an improved production of PHB using an air-lift reactor (ALR) that was fed with a concentrated solution of a carbon source, and was supplemented with an adequate airflow rate. Results: Si
Background: Parkinson's disease and atypical parkinsonism are characterized by motor and non-motor symptoms. As the disease advances, planning for end-of-life (EoL) care becomes increasingly important. However, consensus-based European guidelines for advance care planning and documentation of EoL care preferences for parkinsonism are lacking. Understanding current documentation practices for EoL c
Purpose Visual interpretation of brain amyloid-β (Aβ) PET can be difficult in individuals with borderline Aβ burden. Coregistration with individual MRI is recommended in these cases, which, however, is not always available. This study evaluated coregistration with the early perfusion frames acquired immediately after tracer injection to support the visual interpretation of the late Aβ-frames in PE
Environmental problems, combined with European Union environmental and energy policies shaped to address them, have created pressures for change. Some of these open significant opportunities to renew industries. This report delivers new understanding of the potential of circular economy for sustainable renewal of manufacturing in bio-based industries. With particular focus on novel value chains, i
The temporal aspect of groundwater vulnerability to contaminants such as nitrate is often overlooked, assuming vulnerability has a static nature. This study bridges this gap by employing machine learning with Detecting Breakpoints and Estimating Segments in Trend (DBEST) algorithm to reveal the underlying relationship between nitrate, water table, vegetation cover, and precipitation time series, t
Introduction: A subgroup of severe Traumatic Brain Injury (TBI) patients, known as ultra-severe (us-TBI), is most commonly defined as a post-resuscitation Glasgow Coma Scale (GCS) of 3–5. There is uncertainty on whether these critically injured patients can benefit from neurosurgical intervention. Research question: The available evidence regarding the decision-making and outcome following managem
’Screen time’ has become a catch-all concept for debates on people’s dependence of digital devices in general, and children’s use of media technology in particular, almost exclusively focusing on negative consequences. While children and young people more often than not are at the center of debates around screen time, parents and their everyday practices are held accountable for monitoring, regula
The outcome of a procurement process largely depends upon how it was designed e.g. the terms and conditions that evaluates on what criteria a supplier is awarded a contract. In private sector procurement, evaluation of past performance is natural part of the evaluation process procurement. In public procurement there are more limited possibilities to evaluate past performance based on the rules an
Purpose: To analyse clinical characteristics and risk factors for post-operative endophthalmitis (POE) in a Swedish patient insurance database and compare prevalence of POE with two national quality registers. Methods: We analysed 218 medical records of patients who claimed compensation for POE following ocular surgery from 2010 to 2020. The data were cross-referenced with national quality registe
Predictions of total dissolved solids (TDS) in water bodies including rivers and lakes are challenging but essential for the effective management of water resources in agricultural and drinking water sectors. This study developed a hybrid model combining Grey Wolf Optimization (GWO) and Kernel Extreme Learning Machine (KELM) called GWO-KELM to model TDS in water bodies. Time series data for TDS an
Popular Abstract in English As there is a demand for new antibacterial agents due to antimicrobial resistance, the ability of one kind of microorganisms to produce antimicrobial substances has been evaluated. Then, after determining the antibacterial-producer microorganism, the production of active compound in large scale, followed by optimization the conditions investigated. Next, the bioactive aForty alkaliphiles, which were isolated from samples collected in Eastern Africa, have been screened for production of antibacterial compounds. One of these isolates, Bacillus halodurans B20, was able to produce a prominent amount of antibacterial activity against a Gram-positive bacteria on agar plates [paper I] and selected for further study. Production of the active compound in submerged culti
We study the determinants of remittances to developing countries at different time horizons. Remittances to developing countries nowadays exceed official development assistance and constitute a significant fraction of the disposable income of many households in developing countries. Different hypotheses suggest that remittances are often sent to compensate for low incomes, which may impose a downw
Background/Aim: Type 1 diabetes is an autoimmune disease that involves the development of autoantibodies against pancreatic islet beta-cell antigens, preceding clinical diagnosis by a period of preclinical disease activity. As screening activity to identify autoantibody-positive individuals increases, a rise in presymptomatic type 1 diabetes individuals seeking medical attention is expected. Curre
Introduction: Temporal co-ordination between speech and gestures has been thoroughly studied in natural production. In most cases gesture strokes precede or coincide with the stressed syllable in words that they are semantically associated with.Methods: To understand whether processing of speech and gestures is attuned to such temporal coordination, we investigated the effect of delaying, preposin
Global warming has largely advanced spring vegetation phenology, which has subsequently affected terrestrial carbon and water cycles. However, further shifts in vegetation phenology under future climate change remain unclear. We estimated the start of the growing season (SOS) by applying multiple extraction methods based on the NDVI3g data set, and then parameterized and evaluated 11 spring vegeta
Blood-based biomarkers for screening may guide tau positrion emissition tomography (PET) scan referrals to optimize prognostic evaluation in Alzheimer’s disease. Plasma Aβ42/Aβ40, pTau181, pTau217, pTau231, NfL, and GFAP were measured along with tau-PET in memory clinic patients with subjective cognitive decline, mild cognitive impairment or dementia, in the Swedish BioFINDER-2 study (n = 548) and
Context. The internal kinematics of the Large Magellanic Cloud (LMC) have been studied in unprecedented depth thanks to the excellent quality of the Gaia mission data, thus revealing the disc’s non-axisymmetric structure. Aims. We seek to constrain the LMC bar pattern speed using the astrometric and spectroscopic data from the Gaia mission. Methods. We applied three methods to evaluate the bar pat
Molybdenum clusters, characterized by their unique structure and intriguing catalytic properties, have gained significant attention in recent years. In several existing studies, density functional theory (DFT) methods have been used to find the lowest energy Mo clusters and explore their electronic and magnetic structure. In all cases, with the exception of a single recent study, where a genetic a
