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Our objective was to pilot test an electronic health record-embedded decision support tool to facilitate prostate-specific antigen (PSA) screening discussions in the primary care setting. Methods We pilot-tested a novel decision support tool that was used by 10 primary care physicians (PCPs) for 6 months, followed by a survey. The tool comprised (1) a risk-stratified algorithm, (2) a tool for faci
Background: Existing research shows that older people with severe mental health problems need different forms of support in daily life and in the community to lead an active and meaningful life. A common form of support for people with severe mental health problems in Sweden is attendance at community-based day centres (DCs). However, knowledge of staff and managers’ experiences of how people agei
Background: Resection margin has been associated with overall survival following liver resection for colorectal liver metastasis. The aim of this study was to examine how resection margins of 0.0 mm, 0.1-0.9 mm and =1 mm influence overall survival in patients resected for colorectal liver metastasis in a time of modern perioperative chemotherapy and surgery. Methods: Using data from the national r
Recent studies have explored the influence of obesity and critical illness on ciprofloxacin pharmacokinetics. However, variation across the subpopulation of individuals with obesity admitted to the intensive care unit (ICU) with varying renal function remains unexamined. This study aims to characterize ciprofloxacin pharmacokinetics in ICU patients with obesity and provide dose recommendations for
The multitaper spectrogram, with arithmetic and geometric mean functions, and the ambiguity domain where evaluated on simulated data and real audio samples{. This was done} to determine if they can improve the results, of classification tasks, of the single-taper spectrogram when used as input to a convolutional neural network. The spectrogram used was differentiable to allow for the window length
This thesis investigates simulating X-ray computed tomography with two primary objectives: developing a virtual representation of an X-ray computed tomography scanner and generating labelled synthetic training data for deep learning-based fibre segmentation. A simulation pipeline to generate X-ray projections based on the Beer-Lambert law was developed using the open-source framework gVirtualXray.
Introduction: The transport sector remains a major contributor to global greenhouse gas emissions, driving demand for engine concepts that eliminate carbon and nitrogen-oxide output while reusing existing manufacturing infrastructure. Background: The Argon Power Cycle is an engine concept that replaces air with argon as a working fluid and uses hydrogen as fuel and oxygen as the oxidizer. By explo
Background: Mistletoe extract is a widespread complementary therapy mainly used for quality-of-life improvement in cancer patients. Advanced pancreatic cancer is associated with poor quality of life and better therapies for symptomatic relief are highly needed. Aim: MISTRAL aimed to assess the impact of mistletoe extract on quality of life, body weight, observed costs and blood biomarkers in patie
During land model development, simulated carbon dynamics are often benchmarked against observational data sets to evaluate model performance. Functional relationship benchmarks are the relationship between a driving variable (e.g., temperature) and a response variable (e.g., ecosystem respiration) and are a promising tool for assessing model performance by evaluating modeled sensitivities to chang
A list of 1719 chemical compounds identified from headspace samples of floral scent is presented. The list has been compiled from some 270 published papers, including analyses of 991 species of flowering plants and a few gymnosperms, a sample including seed plants from 90 families and 38 orders. The compounds belong to seven major compound classes, of which the aliphatics, the benzenoids and pheny
We present two new methods for finding a lowest common ancestor (LCA) for each pair of vertices of a directed acyclic graph (dag) on n vertices and m edges. The first method is surprisingly natural and solves the all-pairs LCA problem for the input dag on n vertices and m edges in time 0 (n m). The second method relies on a novel reduction of the all-pairs LCA problem to the problem of finding max
Solar shading devices can significantly reduce cooling loads, improve thermal comfort and reduce potential glare problems in commercial buildings. However, measured data or tools to facilitate a comparison among various shading devices have previously not been available to designers. The Solar Shading Project at Lund University was initiated in 1997 to increase the knowledge on shading devices. Th
A model system consisting of pure triolein and palmitic acid and LipozymeTM, an immobilized lipase (E.C. 3.1.1.3.). has been used to determine the effects of various reaction parameters on the reaction rate and the formation of by-products in the interesterification reaction. The goal was to minimize the level of diglycerides and eliminate trisaturated triglycerides at an endpoint chosen so that t
Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). Higher proportions of free PSA (PSA-F/T) in blood are found in subjects with benign prostatic hyperplasia (BPH) as compared to cancer patients. Utilizing imm
Conventional power plants based on fossil fuel without CO2 capture produce flue gas streams with concentrations Of CO2 between 3% and 15%, contributing to the threat of increasing global warming. Existing capture technologies such as post-combustion flue gas treatment using chemical absorption or pre-combustion carbon removal suffer from significant efficiency penalties as well as major increase i
Popular Abstract in Swedish 1: Tomas Åkerud, doktorand vid Lunds Universitet, har utvecklat en metod för att mäta hur snabbt läkemedelsmolekyler och fettsyror (de naturliga bindarna) tar sig in i och lämnar bindingsfickan i ett protein som är viktigt för fettsyrametabolismen i människa. Proteinet, adipocyt-fettsyrabindande protein (A-FABP), har som funktion att transportera fettsyror, som inte är Nuclear magnetic resonance spectroscopy (NMR) has been used to determine the kinetics of ligand binding to the adipocyte fatty acid-binding protein (A-FABP), as well as the oligomerisation and inter- and intramolecular dynamics of the low molecular weight-protein tyrosine phosphatase (LMW-PTP) in solution. NMR spectroscopy is sensitive to dynamic processes on timescales ranging from picoseconds t
Value added tax (VAT) is a key part of the fiscal revenue of many countries. Yet this broad-based tax on consumer spending exempts financial services. This seems puzzling to many, particularly given the significance of that sector and the size of its value-added in today's world economy. The fact that the European Commission is currently reviewing the tax treatment of financial activities in the E
