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The continuous evolution of photon sources and their instrumentation enables more and new scientific endeavors at ever increasing pace. This technological evolution is accompanied by an exponential growth of data volumes of increasing complexity, which must be addressed by maximizing efficiency of scientific experiments and automation of workflows covering the entire data lifecycle, aiming to redu

Perception is not a passive process but the result of an interaction between an organism and the environment. This is especially clear in haptic perception that depends entirely on tactile exploration of an object. We investigate this idea in a system-level brain model of somatosensory and motor cortex and show how it can use signals from a humanoid robot to categorize different object. The model

It is often necessary in practice to perform identification experiments on systems operating in closed loop. There has been some confusion about the possibilities of successful identification in such cases, evidently due to the fact that certain common methods then fail. A rapidly increasing literature on the problem is briefly surveyed in this paper, and an overview of a particular approach is gi

Presents theory, algorithms and validation results for system identification of continuous-time state-space models from finite input-output sample sequences. The algorithms developed are methods of subspace model identification and stochastic realization adapted to the continuous-time context. The resulting model can be decomposed into an input-output model and a stochastic innovations model. Usin

Herein we describe the discovery of ACP-105 (1), a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone. Compound 1 was developed from a series of compounds found in a HTS screen using the receptor selection and amplification technology (R-SAT). In vivo, 1 improved anabolic parameters in a 2-week chro

Opsin-like immunoreactivity was observed in the retinae and pineal organs of the mouse, rat and guinea pig, and the pineal organ of the cat. In the retina the immunoreaction was restricted to photoreceptor cells, which displayed immunostaining in their perikarya and outer and inner segments. Distinct pinealocytes endowed with characteristic processes were labelled in the pineal organs of the mouse

A retarding-potential method has been used to analyse the energy of electrons produced in the process of generating singly and doubly charged ions in Xe and Ne at 532 and 1064 nm. Energetic electrons observed in Xe at 1064 nm imply that up to 30 photons have been absorbed in the ionisation process, while only 11 photons are necessary to release one electron. The laser intensity dependence of energ

We present an algorithm to combine multiple matrix elements at LO and NLO with a parton shower. We build on the unitarized merging paradigm. The inclusion of higher orders and multiplicities reduce the scale uncertainties for observables sensitive to hard emissions, while preserving the features of inclusive quantities. The combination allows further soft and collinear emissions to be predicted by

The Eigenfactor™ is a journal metric, which was developed by Bergstrom and his colleagues at the University of Washington. They invented the Eigenfactor as a response to the criticism against the use of simple citation counts. The Eigenfactor makes use of the network structure of citations, i.e. citations between journals, and establishes the importance, influence or impact of a journal based on i

In convolutional coding, code sequences have infinite length; thus, a maximum-likelihood decoder implies an infinite delay. Due to memory and delay constraints in practical coding schemes, convolutional codes often are either terminated or decoded by a window decoder. When a window decoder is used, the convolutional code sequence is not terminated; instead, the window decoder estimates information