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At the heart of protein's aggregation are specific molecular events; and how they are modulated by changes in solvent conditions and temperature is key to our understanding and control of aggregation. A certain class of structural fibrous proteins may provide the answer. Indeed, spider silk and silkworm silk proteins have evolved to readily form ‘insoluble’ ordered structures. But, to date little
Students often use incoherent strategies in their problem solving involving force and motion, as revealed, e.g. when they are asked to draw force diagrams for amusement rides involving circular motion, whether in horizontal or vertical planes. Depending on the questions asked, assignments involving circular motion can reveal different types of more or less correct and coherent strategies used by t
Background: Sedation and analgesia are recommended during targeted temperature management (TTM) after cardiac arrest, but there are few data to provide guidance on dosing to bedside clinicians. We evaluated differences in patient-level sedation and analgesia dosing in an international multicenter TTM trial to better characterize current practice and clinically important outcomes. Methods: A total
This paper presents a systematic investigation of the influence of streamturbulence on the pressure forces on a single tube. Grids were used to producedifferent turbulent flow fields with longitudinal integral scale (eddy size)ranging from 0.1 to 0.5 tube diameters and turbulence intensities ranging from0.1 to 3-2 %. The measurements were carried out at two Reynolds numbers, 2.7 - 10 and U.1-104 ,
Artikeln kompletterar två tidigare texter i tidskriften Ale 2020: 2–3 om Lyngsjö i Skåne. Elisabeth Reuterswärd söker här bakgrunden till dopfuntens ovanliga motiv, medan Sten Skansjö förklarar utvecklingen i socknen över tid. Denna artikel uppmärksammar, att dopfunten har spår av bemålning, kommenterar kyrkans herrskapsgalleri, korrigerar upplysningarna om antalet gyllene altare i Norden, visar aThe article presents a supplement to two earlier texts in the periodical Ale 2020: 2–3 on Lyngsjö in Scania. Elisabeth Reuterswärd here seeks the background for the unusual motif of the baptismal font, where Sten Skansjö tries to explain the development in the parish over time. The present article draws attention to the fact that the font has traces of painting, comments on the upper gallery of th
We measured absolute cross sections for neutron transfer channels populated in the Rb94+Pb208 binary reaction. Cross sections have been extracted identifying directly the lead isotopes with the high efficiency MINIBALL γ-ray array coupled to a particle detector combined with a radioactive Rb94 beam delivered at Elab=6.2 MeV/nucleon by the HIE-ISOLDE facility. We observed sizable cross sections in
Intellectual property rights (IPRs) represent a key concern for researchers and industry in basically all (high-tech) sectors. IPRs regularly figure prominently in scientific journals and at scientific conferences and lead to dedicated workshops to increase the awareness and “IPR savviness” of scientists. In 2015, Biotechnology Journal published a report from an expert meeting on “Synthetic Biolog
Ikaros is an open framework for system-level brain modeling and real-time robot control. Version 2 of the system includes a range of computational components that implements various algorithms and methods ranging from models of neural circuits to control systems and hardware interfaces for robot. Ikaros supports the design and implementation of large-scale computation models using a flow programmi
For patients with end-stage respiratory diseases, such as COPD, interstitial lung diseases and cystic fibrosis, lung transplantation remains the only treatable option. However, due to increasing demand and limited availability of donor lungs, risk of complications such as acute and chronic rejection, and adverse effects of immunosuppressive treatments, this is not an alternative for the majority o
A reliable method of optimization of polymer gears remains, to date, an open challenge, due to the lack of specific material characterization of polymers and to the complex nonlinear relations between different geometric and operating parameters. For spur and helical gears, the authors herein have developed the optimization algorithm, which primarily enables variation of geometry according to vari
In order to stimulate benchmarking and comparisons between different municipal activities, the Swedish Association of Local Authorities and Regions (SALAR) and the Ministry of Finance in the year of 2007 initiated a voluntary nationwide Swedish benchmarking project (NBP) in order to develop new measures that capture the relationship between cost and quality. The ambition is that the new measures s
Ministerial portfolios are the most obvious payoffs for parties entering a governing coalition in parliamentary democracies. This renders the bargaining over portfolios an important phase of the government formation process. The question of ‘who gets what, and why?’ in terms of ministerial remits has not yet received much attention by coalition or party scholars. This article focuses on this quali
