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Background and Purpose— Although stroke is strongly associated with hypertension, some individuals with normal blood pressure (BP) experience a stroke. This prospective study explored risk factors for stroke in subjects with normal BP. Methods— A total of 11 228 men and 17 174 women, 45 to 73 years old, were examined in a population-based cohort study. Normal BP was defined as BP <140/90 mm Hg an

This article addresses two main questions both of which are raised by Risto Nurmela’s comparison between Judaism and Christianity, the first being the statement that Christology ”of course” is the dividing line between the two religions. This assertion must be refined in order to be applicable since (1) it gives vent to only one of two perspectives (i.e. it articulates only the Christian position)

Aims: Guidelines for cardiovascular disease (CVD) prevention cite high levels of low-density lipoprotein cholesterol (LDL-C) as a major risk factor and recommend LDL-C goals for various risk groups. Lifestyle changes are advised as first-line treatment for patients with high cholesterol, and statins are recommended in high-risk patients. The From The Heart study investigated current practice for t

Objectives To ascertain whether the risk for congenital malformations is increased in pregnancies with deviating fetal growth, i.e. in those in which the estimated date of delivery (EDD) was postponed more than 1 week at the second- trimester ultrasound fetometry scan, or those suspected of intrauterine growth restriction at routine ultrasound fetometry in the third trimester. Methods The study pe

We discuss the main properties of the Galactic globular cluster (GC)blue straggler stars (BSSs), as inferred from our new catalog containingnearly 3000 BSSs. The catalog has been extracted from thephotometrically homogeneous V versus (B-V) color-magnitude diagrams(CMDs) of 56 GCs, based on Wide Field Planetary Camera 2 images of theircentral cores. In our analysis, we used consistent relative dist

The way the fuel is introduced into the combustion chamber is one of the most important parameters for the power output and the generation of emissions in the combustion of liquid fuels. The interaction beween the turbulent gas flow field and the liquid fuel droplets, the vaporisation of them and the mixing of the gaseous fuel with the ambient air that are vital parameters in the combustion proces

BACKGROUND: Recent studies have suggested that reactive oxygen species may be involved in the development of diabetic retinopathy. METHODS: Nitro blue tetrazolium (NBT) staining, a marker of reductants which may be induced by free radicals such as superoxide, and catalase activity, as an indirect measure of hydrogen peroxide (H2O2) generation, were studied in the rat retina in three conditions kno

The aim of this study was to evaluate the relationship between respiratory symptoms, lung function and inflammatory markers in 'healthy' smokers. The study population was recruited from an epidemiological study with subjects of the same age, 60 years. Only smokers who considered themselves healthy (n=58) and a random sample of never-smokers (n=34) were investigated. All subjects underwent lung fun

Background No data exist regarding mortality rate in young patients with a first-time anterior shoulder dislocation. A cohort of 255 patients aged 1240 years had a primary anterior shoulder dislocation during the years 1978 and 1979. After 10 years, 9 of the patients had died-which is a high figure for this cohort of patients. The question thus arose as to whether these patients had an increased m

Objective: To develop evidence based recommendations for the management of hip osteoarthritis (OA). Methods: The multidisciplinary guideline development group comprised 18 rheumatologists, 4 orthopaedic surgeons, and 1 epidemiologist, representing 14 European countries. Each participant contributed up to 10 propositions describing key clinical aspects of hip OA management. Ten final recommendation

Popular Abstract in Swedish Denna avhandling har två huvudsakliga syften. Det första syftet är att bidra med en fördjupad kunskap kring demokratins begränsningar och möjligheter i en tid av tilltagande globalisering och gränsöverskridande politisk verksamhet. Även om detta syfte i hög grad aktualiserar frågan om den nationella demokratins fortsatta verkansmöjligheter, är fokus ställd på möjligheteThis book has two overarching objectives. Firstly, in an age of increasing globalization and cross-border political activities it seeks to contribute to the debate on the limits and possibilities of democracy in the present and in the future. Even though this objective brings to the fore the issue of democracy in a national context, the main ambition is to examine democratic values and institution

Engineering heat transfer problems are very often of a complex nature and most often no analytical solutions exist. One way to create solutions to such problems is to apply numerical methods. This study concerns heat transfer problems with coupled conduction, convection and thermal radiation. Five important but different engineering problems are considered: 1) The transient temperature distributi

The variable region 1 to 3 (V1-V3) of the HIV-1 envelope plays an important role in coreceptor usage. Early in infection HIV- 1 is using CCR5 as coreceptor to enter target cells (R5 viruses) whereas viruses using CXCR4 as coreceptor (X4 viruses) may appear later in infection. This broadening or switch in coreceptor usage is associated with progression to AIDS. In my thesis work, we have compared t

Alpha-satellite sequences are found in the centromeric region of all human chromosomes and have been implicated in centromeric function. We describe the structure and behaviour of chromosomes containing amplified human alphoid DNA from chromosome 12, in an osteosarcoma cell line (OSA) and an atypical lipomatous tumour (ALT). In OSA, the amplified material was detected in one large marker chromosom

Background: The expression of gene batteries, genomic units of functionally linked genes which are activated by similar sets of cis- and trans-acting regulators, has been proposed as a major determinant of cell specialization in metazoans. We developed a predictive procedure to screen the mouse and human genomes and transcriptomes for cases of gene-battery-like regulation. Results: In a screen tha