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Previous reports have suggested a role for polycyclic aromatic hydrocarbons in the pathogenesis of atherosclerosis. Therefore, the effects of benzpyren (BP) and dimethylbenzanthracene (DMBA) on the arterial smooth muscle cell (SMC) in culture were studied. DMBA increased the proliferation of bovine and rabbit SMC but not of human embryonal fibroblasts or human SMC. BP did not significantly influen

Global warming will unquestionably increase the impact of heat on individuals who work in already hot workplaces in hot climate areas. The increasing prevalence of this environmental health risk requires the improvement of assessment methods linked to meteorological data. Such new methods will help to reveal the size of the problem and design appropriate interventions at individual, workplace and

It is known that listeners can predict upcoming words based on constraining contexts (e.g. DeLong et al., 2005). In a recent study, we proposed a left frontal brain potential, the pre-activation negativity, PrAN (Söderström et al., 2016), thought to reflect pre-activation of expected word continuations. Time-locked to word-initial fragments, PrAN’s amplitude was found to increase in a 136-280 ms t

This paper presents a study of the physical limitations for radio frequency absorption in gold nanoparticle (GNP) suspensions. A spherical geometry is considered consisting of a spherical suspension of colloidal GNPs characterized as an arbitrary passive dielectric material which is immersed in an arbitrary lossy medium. A relative heating coefficient and a corresponding optimal near field excitat

Pancreastatin, a C-terminally amidated peptide derived from chromogranin A, is known to inhibit insulin secretion, pancreatic enzyme release, and gastric acid secretion. It also inhibits parathyroid hormone (PTH) secretion in animals. The physiologic and clinical relevance of pancreastatin in humans, however, is not known. Because pancreastatin has been found in parathyroid adenomas, we investigat

MicroRNAs (miRNAs) are cellular, short, non-coding ribonucleotides acting as endogenous posttranscriptional repressors following incorporation in the RNA-induced silencing complex. Despite being chemically and mechanistically very similar, miRNAs exert a multitude of different cellular effects by acting on mRNA species, whose gene-products partake in a wide array of processes.Here, the aim was to

Purpose We validate the usefulness of laser-induced autofluorescence for the detection of bladder carcinoma. Materials and Methods We obtained and analyzed fluorescence spectra from 75 patients in whom bladder cancer was suspected. Tissue fluorescence was excited by a nitrogen laser using a quartz optical fiber placed in gentle contact with the area of interest. The laser-induced autofluorescence

Increased expression of Bim, a pro-apoptotic member of the Bcl-2 family, has been shown to be critical for neuronal apoptosis. To study the involvement of Bim in injury-induced cell death in retina, Bim expression was studied in normal rat retina and in retina after optic nerve transection using quantitative RT-PCR and immunohistochemistry. As a complement to this, the apoptotic regulators Bax, Bc

Objectives: The purpose of this presentation is to discuss Sweden’s national recommendations for mental health treatment provided to self-harming individuals in the country. The recommendations were based upon a Self-Harm Quality Standard (2013) published by the National Institute for Health and Care Excellence (NICE) adapted to Swedish health care and cultural context. Methods: A review and synt

BACKGROUND: The immune response against discordant xenografts in the brain is incompletely understood and remains a major obstacle for future clinical applications of xenogeneic neural tissue transplants in neurodegenerative disorders. To determine the role of antibodies in the rejection process, we compared graft survival and immune reactions between immunoglobulin deficient (IgKO) and normal mic

Ventral mesencephalic tissue from aborted human fetuses (age, 6-7 weeks' postconception) was implanted unilaterally into the putamen using stereotaxic surgery in 2 immunosuppressed patients (Patients 3 and 4 in our series) with advanced idiopathic Parkinson's disease. Tissue from 4 fetuses was grafted to each patient. Compared with our previous 2 patients, the following changes in the grafting pro

Stars in open clusters are expected to share an identical abundance pattern. Establishing the level of chemical homogeneity in a given open cluster deserves further study as it is the basis of the concept of chemical tagging to unravel the history of theMilkyWay.M67 is particularly interesting given its solar metallicity and age as well as being a dense cluster environment.We conducted a strictly

The purpose of this series of three cross-sectional studies was to identify typical syndromes of self-reported externalizing and internalizing problems, and examine their overlap, among adolescent girls and young women in Swedish special residential homes for young people (N = 713). The associations with some family background factors were also investigated. Data came from a research register at t

In order to obtain more detailed characteristics and information in highly turbulent flames, for a better understanding of the transient behavior of eddies in such flames, a measurement technique with sufficient temporal resolution is requested. However, the probing of species distributions relevant in combustion (e.g. OH, CH2O) with ultra-high-speed laser diagnostics still remains a challenge. Nd

In the region of Three Gorges Reservoir (TGR) in China, there has been occurrence of several frequent earthquakes of moderate intensity since reservoir impounding occurred in 2003. These earthquakes are generally believed to be induced by reservoir impoundment and water-level variations. Usually, the geo-stress will change, when natural earthquakes occur. Following this principle, this paper adopt

BACKGROUND: There are limited data on the long-term outcome and on factors influencing the prognosis in patients with cerebellar infarcts treated with surgical decompression.METHODS: Thirty-two patients (age 64.3 ± 9.9 years) with expansive unilateral cerebellar infarcts were retrospectively evaluated. All patients were treated with ventriculostomy, suboccipital decompressive craniectomy and remov

Objectives: To investigate the prevalence of obesity among different types of employment status in the Italian working population, and to examine associated risk factors. Material and Methods: Cross-sectional survey of 36 814 people that declared to have been occupied with the same type of contract for at least 5 years was analyzed. Multivariable logistic regression models were built considering w

Sweden has a small internal market and, thus, bases its wealth on the exports. Following the so-called Rhen-Meidner model this objective is also achieved thought the solidarity wage: wages are parametrized on a lead-ing sector (generally the major export industry) and because each firm faces the same labour cost they are obliged to base their competitiveness on higher productivity levels (reached