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Review of Diagnosis-Related Group-Based Financing of Hospital Care

Since the 1990s, diagnosis-related group (DRG)-based payment systems were gradually introduced in many countries. The main design characteristics of a DRG-based payment system are an exhaustive patient case classification system (ie, the system of diagnosis-related groupings) and the payment formula, which is based on the base rate multiplied by a relative cost weight specific for each DRG. Cases

Can didactic continuing education improve clinical decision making and reduce cost of quality? : Evidence from a case study

INTRODUCTION: Administration of human serum albumin (HSA) solutions for the resuscitation of critically ill patients remains controversial. The objective of this study was to assess the effect of continuing medical education (CME) on health care professionals' clinical decision making with regard to HSA administration and the costs of quality (COQ). A quasi-experimental study of time series associ

Multiple spectral channels in branchiopods. I. Vision in dim light and neural correlates

Animals that have true color vision possess several spectral classes of photoreceptors. Pancrustaceans (Hexapoda+Crustacea) that integrate spectral information about their reconstructed visual world do so from photoreceptor terminals supplying their second optic neuropils, with subsequent participation of the third (lobula) and deeper centers (optic foci). Here, we describe experiments and correla

Complications, long-term outcome and quality of life following Surgisis® and muscle-covered implants in immediate breast reconstruction : a case-control study with a 6-year follow-up

Background: Matrices are now commonly used in breast reconstruction, but the scientific evidence is still scares. The main aim was to compare complications and the need for corrections in immediate breast reconstruction with the porcine-derived Surgisis® with the traditional muscle-covered technique. The secondary aim was to compare long-term quality of life and satisfaction. Methods: All consecut

Analysis of the apparent nuclear modification in peripheral Pb–Pb collisions at 5.02 TeV

Charged-particle spectra at midrapidity are measured in Pb–Pb collisions at the centre-of-mass energy per nucleon–nucleon pair s NN =5.02 TeV and presented in centrality classes ranging from most central (0–5%) to most peripheral (95–100%) collisions. Possible medium effects are quantified using the nuclear modification factor (R AA ) by comparing the measured spectra with those from proton–proton

A local Monte Carlo framework for coherent QCD parton energy loss

Monte Carlo (MC) simulations are the standard tool for describing jet-like multi-particle final states. To apply them to the simulation of medium-modified jets in heavy ion collisions, a probabilistic implementation of medium-induced quantum interference effects is needed. Here, we analyze in detail how the quantum interference effects included in the Baier-Dokshitzer-Mueller-Peigné-Schiff–Zakharo

Towards the modelling of pedestrian wind speed using high-resolution digital surface models and statistical methods

Wind is a complex phenomenon and a critical fac-tor in assessing climatic conditions and pedestrian comfortwithin cities. To obtain spatial information on near-groundwind speed, 3D computational fluid dynamics (CFD) model-ling is often used. This is a computationally intensive methodwhich requires extensive computer resources and is time con-suming. By using a simpler 2D method, larger areas can b

Inland dunes of Sweden, an aeolian archive

Sweden is not famous for its dune fields, and rightfully so; compared to most other countries of the world the Swedish dune fields are humble in size. Also, many of them are inactive and covered by vegetation. Due to this the dune fields of Sweden have been left largely unexplored the last decades. This is unfortunate since many of the dune fields in Sweden are valuable palaeo-environmental time c

Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia

Glutamatergic transmission is an important factor in the development of neuronal death following transient cerebral ischemia. In this investigation the effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on neuronal damage were studied in rats exposed to 10 min of transient cerebral ischemia induced by bilateral common carotid occlusion combined with hypotension. The animals w

The Southern Sweden Adolescent Allergy-Cohort : Prevalence of allergic diseases and cross-sectional associations with individual and social factors

Objectives: Asthma and allergic diseases are the most frequent chronic diseases in childhood worldwide, and considered a burden for the affected children and their families. The diseases impose an economic burden on society if not diagnosed and treated properly and management of and these diseases are challenging for healthcare professionals. The aim of the present investigation was to assess the

Immunogenicity and safety of pneumococcal vaccination in patients with systemic sclerosis

Objective. To study the impact of disease and treatment with DMARDs on antibody response elicited by either pneumococcal conjugate vaccine (PCV13) or pneumococcal polysaccharide vaccine (PPV23) in patients with SSc. Methods. Forty-four SSc patients and 49 controls received a dose of either PCV13 or PPV23. Twelve patients were treated with DMARDs. Antibody levels to pneumococcal polysaccharides 6B

Simulation of NOM removal by capillary NF : A numerical method for full-scale plant design

The removal of natural organic matter (NOM) from boreal lake water by a novel capillary nanofiltration (NF) membrane was predicted using a computational fluid dynamics (CFD) modelling approach. The 2-dimensional axis-symmetric model was based on a 48 m3/day NF pilot plant operating in cross-flow mode on water containing 8 mg/L total organic carbon (TOC) at fluxes ranging from 10 to 25 L/m2/h and v

The effect of fatty acid binding in the acid isomerizations of albumin investigated with a continuous acidification method

The protein Human Serum Albumin (HSA) is known to undergo conformational transitions towards partially unfolded forms triggered by acidification below pH 4.5. The extent of Fatty Acids (FA) binding has been thought to have an impact on the conformational equilibrium between the native and acid forms and to be a possible explanation for the observation of more than one band in early electrophoretic

Supply chain risk management : An idea generator for managing disruption risks in supply chains

This report presents an idea generator which is intended to be used when searching for new options for handling the disruption risks of the company. The initial step of the search is usually characterized as a “brainstorming session”, i.e. to generate as many risk management options as possible, and preferably untraditional ones. This is where the idea generator may be of great assistance; it cons

On the colloidal and molecular aspects of peptide self-assembly

Peptide self-assembly is a spontaneous process, ubiquitous in nature for the creation of highly ordered and complex biological structures, making it a sought after technique in the development of novel biocompatible materials. The process is also strongly associated with various neurodegenerative diseases in the formation of amyloid plaques in diseases such as Alzheimer’s and Parkinson’s, where fu