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Objective: To report national data on diagnostics and treatment of upper tract urothelial carcinoma (UTUC) from the Swedish National Registry of Urinary Bladder Cancer (SNRUBC). Patients and methods: Data from 2015 to 2021 were retrieved, and descriptive analyses were performed regarding incidence, diagnostic modalities, preoperative tumor staging, quality indicators for treatment including the us
BACKGROUND: There is a paucity of data on the incidence of central venous catheter tip misplacements after the implementation of ultrasound guidance during insertion. The aims of the present study were to determine the incidence of tip misplacements and to identify independent variables associated with tip misplacement.METHODS: All jugular and subclavian central venous catheter insertions in patie
Shedder status is defined as the propensity of an individual to leave DNA behind on touched items or surfaces and has been suggested as one of the major factors influencing DNA transfer. However, little is known about whether shedder status is a constant property of an individual across multiple measurements or when the environmental conditions are changed. We have assessed DNA depositions of six
Most epithelial ovarian cancer (EOC) patients are diagnosed with peritoneal dissemination. Cellular interactions are an important aspect of EOC cells when they detach from the primary site of the ovary. However, the mechanism remains underexplored. Our study aimed to reveal the role of chondroitin sulfate proteoglycan 4 (CSPG4) in EOC with a major focus on cell–cell interactions. We examined the e
Objectives: To assess whether extended surveillance with repeated computed tomography (CT) scans for patients with clinical stage IIA (CS IIA; <2 cm abdominal node involvement) and negative markers (Mk−) non-seminomatous germ cell tumours (NSGCTs) can identify those with true CS I. To assess the rate of benign lymph nodes, teratoma, and viable cancer in retroperitoneal lymph node dissection (RPLND
Hippocampal sulcal cavities (HSCs) are frequently observed on MRI, but their etiology and relevance is unclear. HSCs may be anatomical variations, or result from pathology. We assessed the presence of HSCs, and their cross-sectional association with demographics, vascular risk factors and cognitive functioning in two study samples. Within a random sample of 92 patients with vascular disease from t
Introduction: High-mobility group box 1 (HMGB1) is a non-histone nuclear protein and can be extracellularly secreted to induce sterile inflammation. Although uterine deletion of HMGB1 causes implantation and decidualization defects, how secreted HMGB1 is involved in mouse early pregnancy is still unknown. Methods: Mouse models, mouse primary endometrial cells and human endometrial cell lines were
Background: A pre-existing, well-established European influenza surveillance network known as I-MOVE enabled the rapid implementation of a European multi-country COVID-19 hospital surveillance network for surveillance of hospitalized COVID-19 cases in early 2020. This network included 257 hospitals in 11 surveillance sites across nine countries. We aimed to identify whether the surveillance object
Type-2 diabetes (T2D) worsens stroke recovery, amplifying post-stroke disabilities. Currently, there are no therapies targeting this important clinical problem. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are potent anti-diabetic drugs that also efficiently reduce cardiovascular death and heart failure. In addition, SGLT2i facilitate several processes implicated in stroke recovery. However,
The response of clouds to the changes in climate is uncertain, and the representation of the cloud-climate feedback is a key challenge in the global circulation models (GCM) for future climate projections. Factors contributing to this uncertainty include processes that involve particles of various sizes and phases, as well as the interactions between these particles and the surrounding atmosphere.
Silica has rarely been used as a seed particle material in acoustic trapping of nanoparticles. Here we use fluorescent nanoparticles, which are frequently used as a model system, to demonstrate that throughput and nanoparticle trapping efficiency can be improved by using silica seed particles as opposed to traditionally used polystyrene seed particles. The 10 times larger dipole scattering coeffic
Aim: How the ability of plants to move towards newly favourable habitats (dispersal limitation) impacts the change of biome distribution and transition under fast climate warming is still debated. Analysing vegetation change in the past may help to clarify the relative importance of underlying ecological processes such as climate, biotic interactions, and dispersal. In this study, we investigated
In this chapter, focus is on the period 1945-1960 and the discussion is divided into three thematic sections: First, macro-economic structures including growth trends and the composition of the economies. Second, colonial budgets including state finance, fiscal capacity, and economic policy. Third, changes in occupations, incomes, and living standards primarily for the African subjects. The text p
A previous systematic review has shown associations between exposure to high temperatures and negative birth outcomes. To date, a scoping review for heat indices and their use to measure effects of heat on maternal and perinatal health has not been considered.Objectives To provide a scoping review on heat stress and indices for those interested in the epidemiology and working in extreme heat and m
The ubiquitous presence of microplastics in the aquatic environment has raised concern about their potential impacts on and risks to the biota. While the presence of microplastics in a marine environment has been well studied, the impact of microplastic contamination in freshwater bodies is understudied. In the present study, baseline data about contamination with microplastics in Lake Guaíba in s
BACKGROUND: Clinical notes are ubiquitous resources offering potential value in optimizing critical care via data mining technologies.OBJECTIVE: To determine the predictive value of clinical notes as prognostic markers of 1-year all-cause mortality among people with diabetes following critical care.MATERIALS AND METHODS: Mortality of diabetes patients were predicted using three cohorts of clinical
Spark-ignition (SI) aviation piston engines are widely used on light helicopters and unmanned aerial vehicles (UAVs) because of the high-power density and ultra-high cost performance. Kerosene with high flash point is expected to improve safety of aforementioned aircrafts by replacing gasoline. However, in spark-ignition mode, kerosene is difficult to mix and is easy to knock. Short-chain alcohols
Introduction: Surgeons can reduce incisional hernia formation by adhering to standardized techniques for incisional wound closure. This is often neglected by the time a long operation is to be ended and can lead to the risk of developing an incisional hernia or a wound rupture. To address this issue, a suturing machine (Suture-TOOL) was developed for swift and standardized abdominal closure. The a
