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Macroarray analysis was used to compare equal amounts of cDNA from wild-type and rd/rd (retinal degeneration) mice, collected at P90 when photoreceptor degeneration is virtually complete. A stronger signal for the glycolytic enzyme phosphoglucose isomerase (Gpi1) was observed in the rd/rd sample. Extracellularly, Gpi1 may act as a cytokine, independently described as neuroleukin and autocrine moti

The aim of this study is to understand the mechanisms behind the diffusion of fired bricks in Hellenistic Europe, initiated in the north Aegean in the 4th century BC. To this end, a social diffusion model is used to simulate the available archaeological data pertaining to this process. The starting point in the construction of the model is the assumption that different categories of people contrib

The ordered c(2×2) Na on Al(100) and (3 × 3) R30°K on Al(111) structures formed at either 100 K or at room temperature are studied by high-resolution core-level spectroscopy. For both systems equal alkali coverages are found at these two temperatures. The core-level spectra, however, show strong changes with temperature. This behavior leads to the surprising conclusion that annealing at room tempe

Background The mechanism underlying the association between urban birth/upbringing and increased schizophrenia risk is unknown. This study explored whether an urban effect might be present in a low-income country setting, where the 'urban' environment may have radically different components, for example urban architecture, pollution levels or social cohesion. Aims To investigate the potential asso

The invasion of alien species and genotypes is an increasing concern in contemporary ecology. A central question is, what life-history traits enable invasion amidst populations of wild species and conventional cultivars? In order to invade, the initially rare species must perform better than their resident competitors. We conducted a mathematical analysis and simulation of a two-species extension

The mobile telecommunication network is growing year after year and it will soon move into the high speed 5G and Internet of Things technology. These new technologies will improve the throughput and data connectivity and due to that the energy consumption in radio and digital units may increase in a Radio Base Station (RBS). There are more than 500 000 off-grid RBSs in the world which are powered

This thesis will clarify the notion of individual concern and its use by the ECJ, through an analysis of case law and a Lockean analysis of the EU. The thesis takes it outset in the case law of the ECJ and will show, through a thorough analysis of a selected part of the case law, that this is inconsistent and unstable, leaving individuals with legal uncertainty and little hope of accessing the CFI

This paper presents the results of a 4-y investigation of C-14 in different waste streams of both boiling water reactors (BWRs) and pressurized water reactors (PWRs). Due to the potential impact of C-14 on human health, minimizing waste and releases from the nuclear power industry is of considerable interest. The experimental data and conclusions may be implemented to select appropriate waste mana

Popular Abstract in Swedish Denna avhandling handlar om stora nätverk av oscillatorer. En oscillator är ett system som beter sig periodiskt. Speciellt handlar avhandlingen om oscillatorer som har ett typiskt beteende. En egenskap som varje sådan oscillator har är den naturliga frekvens med vilken beteendet upprepas. Om vi stör oscillatorn, så återvänder den så småningom till sitt typiska beteende.This thesis deals with large networks of limit cycle oscillators. A limit cycle oscillator is a dynamical system that has a periodic attractor in phase space, and is defined in continuous time. To each such oscillator one can associate a natural frequency. Virtually all biological systems that show periodic oscillations can be seen as limit cycle oscillators. The same is true for oscillating mecha

Tin was a vital commodity in times past. In central Europe, the earliest finds of tin-bronze date to about 2200 bc, while in Greece they are c. 400-500 years earlier. While there is evidence for prehistoric copper mining-for example, in the Alps or mainland Greece, among other places-the provenance of the contemporary tin is still an unsolved problem. This work deals with a new approach for tracin

The rise in prevalence and severity of obesity and related diseases imposes increasing costs on society. The objective of this thesis is to discuss and estimate the possible effects of a so-called fat tax as a tool for minimizing these costs. Two alternatives for differentiation of the value-added tax (VAT) on food are compared. The first alternative is an increase of the VAT levied on food contai

In enology, "Brett" character refers to the wine spoilage caused by the yeast Dekkera/Brettanomyces bruxellensis and its production of volatile phenolic off-flavours. However, the spoilage potential of this yeast is strain-dependent. Therefore, a rapid and reliable recognition at the strain level is a key point to avoid serious economic losses. The present work provides an operative tool to assess

Mosasaurs are an extinct group of secondarily adapted aquatic lizards that became the dominant marine tetrapods in the Late Cretaceous oceans. They continuously shed and replaced their teeth in order to maintain a functional dentition at all times; however, the process of tooth development in mosasaurs is still incompletely known. Based on incremental line width measurements and growth line counts

The study focuses on mapping spatiotemporal patterns and detecting the potential drivers of traffic congestion with multi-source data. First, based on real-time traffic data retrieved from an online map, the k-means clustering algorithm was applied to classify the spatiotemporal distribution of congested roads. Then, we applied a geographical detector (Geo-detector) to mine the potential factors f

Patient-reported outcome measures (PROMs) are the only systematic approach through which the patient's perspective can be considered by surgeons (in determining a procedure's efficacy or appropriateness) or healthcare systems (in the context of value-based healthcare). PROMs in registries enable international comparison of patient-centered outcomes after total joint arthroplasty, but the extent to

Decentralized anaerobic digestion (AD) of manure and organic residues is a possible strategy to improve carbon and nutrient cycling within agricultural regions, meanwhile generating renewable energy. To date, there has been limited adoption of decentralized AD technology in industrialized countries owing to low profitability for plant operators. There remains a need to demonstrate the wider sustai