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The cortico-basal ganglia-thalamic (CBT) circuit is thought to be involved in control of voluntary and goal-directed movements and action selection. Dopamine is known to play a crucial role in this circuit and regulating its activity. The important role of dopamine is particularly evident in Parkinson’s patients, where dopaminergic cells are dying and motor impairments follow. While dopamine repla

Rapidly developing technology and an increasing number of products containing electrical or electronic functions, has led to discarded electrical and electronic equipment (EEE) being one of the fastest growing waste streams. The European Union (EU) has enacted several iterations of the Waste Electrical and Electronic Equipment (WEEE) Directive to address this complex waste stream. However, recycli

Tissue factor (TF) expressed at the protein level includes two isoforms: The membrane‑bound full‑length TF (flTF) and the soluble alternatively spliced TF (asTF). flTF is the major thrombogenic form of TF, whereas asTF is more closely associated with tumor growth, angiogenesis, metastasis and cell growth. In order to further investigate the different expression and functions of TF splice variants,

Oxygen consumption, lactate production and tissue contents of ATP, phosphocreatine (PCr) and lactate were measured following readdition of K+ to K+-depleted rat portal veins, in order to study the energy turnover associated with Na+/K+ pumping. During incubation in K+-free medium at 37 degrees C spontaneous contractions disappeared in 10-20 min. Readdition of K+ (5.9 mM) after 40 min K+-free incub

Glacial rebound modelling, to establish constraints on past ice sheets from the observational evidence of palaeo-shoreline elevations, is well established for the post- Last Glacial Maximum (post-LGM) period, for which the observational evidence is relatively abundant and well distributed spatially and in time. This is particularly the case for Scandinavia. For the earlier part of the glacial cycl

Jet shapes have been measured in inclusive jet production in proton-proton collisions at root s = 7 TeV using 3 pb(-1) of data recorded by the ATLAS experiment at the LHC. Jets are reconstructed using the anti-k(t) algorithm with transverse momentum 30 GeV < p(T) < 600 GeV and rapidity in the region vertical bar y vertical bar < 2.8. The data are corrected for detector effects and compared to seve

“The death of distance” has become the battle cry of a modern generation of managers, policy makers and scientists who embrace the new globalized economy and its promise of frictionless exchange across the world. While highly influential, this view does not, however, stand unchallenged. Over the last 15 years, there has been a growing interest in the geographical clustering of industry. Well-known

This licentiate thesis examines the development of internationalization of production in Kazakhstan and its economic implications over the period 1991-2010. The main objectives of the thesis are to investigate the role of foreign investment and TNCs in the economic growth of Kazakhstan since its independence in 1991 and onward, to explore the motives that foreign enterprises have for investing in

Abstract In the field of occupational hygiene much consideration is devoted to the uptake through the human airways, but there are also reports of irritations, complaints and hazards or potential hazards due to particle deposition onto the eyes. There is a need for data regarding the dependence of the deposition rate on particle size and environmental parameters in order to formulate sampling crit

Second-generation bioethanol produced from various lignocellulosic materials, such as wood, agricultural or forest residues, has the potential to be a valuable substitute for, or a complement to, gasoline. One of the crucial steps in the ethanol production is the hydrolysis of the hemicellulose and cellulose to monomer sugars. The most promising method for hydrolysis of cellulose to glucose is by

The starting point in this thesis is stroke inflicted individuals’ stories about their experience of stroke, relations in everyday life, and their relations and attempts to return to paid work with the objective of gaining a further understanding of what happens when inflicted by illness and/or disability in working age. Furthermore, it aims at understanding how social relations and ruling relatio

In the last two decades the introduction of mammographic screening in the Western world has increased the number of diagnosed ductal carcinomas in situ (DCIS) considerably. In situ carcinoma of the breast is considered a heterogeneous disease, the natural history of which is not well known. Thus, appropriate treatment needs to be established. For this reason, a randomised trial studying the effect

Rationale Vitamin D has been shown to be involved in the host immune response toward Mycobacterium tuberculosis. Objectives: To test whether vitamin D supplementation of patients with tuberculosis (TB) improved clinical outcome and reduced mortality. Methods: We conducted a randomized, double-blind, place-bocontrolled trial in TB clinics at a demographic surveillance site in Guinea-Bissau. We incl

The aim of this work was to determine the extent to which soot is formed and if there are any ways of reducing the formation of soot. In order to determine if soot formation will be a critical issue for the reverse flow reforming process modeling of the process was undertaken. The reformer was modeled using a detailed reaction mechanism to describe the kinetics of soot formation.The results of the

One of the main objectives of this series is to explore the relationship between Islam, nationalism and citizenship in its diverse expressions. The series intends to provide a space for approaches that recognize the potential of Islam to permeate and inspire national forms of identification, and systems of government as well as its capacity to inspire oppositional politics, alternative modes of be

Wrap Your Troubles into Dreams, är ett praktikbaserat forskningsprojekt. Undersökningen berör stadsomvandlingsprocesser i Stockholmsområdet, speglade genom två politiska förhållningssätt gestaltat i staden: genomförandet av det funktionsseparerade Stockholms City (under 1960-talet) och de senaste decenniernas privatisering av stadsrummet. I forskningen har jag utgått från två platser som i motreakWrap Your Troubles into Dreams is a practice-based artistic research project. The study investigates city transformation processes in the Stockholm area, by viewing them through two political attitudes expressed in the city; the introduction of the function-separated Stockholm City area (during the 1960s) and the privatisation of urban space during the last few decades. I have based my research on

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Vilka är egentligen ”de äldre”? Vad innebär det att vara pensionär? Hur ska man åldras på rätt sätt? Frågor som dessa har under det nyss avslutade århundradet ställts och besvarats på många oliks sätt, beroende av sammanhang och tidsperiod. I vissa situationer har de äldres olikhet lyfts fram, i andra deras likhet. Ibland har åldrandetThe aim of the dissertation is to describe images of old age in the magazines of Sweden’s two largest pensioner organizations, and explain the character of those images in relation to the temporal contexts of the organizations and their aim to act as the representatives of pensioners. The study is based on the 329 and 330 magazines (1941–1995) that the organizations have submitted to attract membe

Popular Abstract in Swedish SAMMANFATTNING PÅ SVENSKA (Swedish summary) Ultraljud används sedan 1970-talet rutinmässigt under graviditet. Undersökningen görs vanligen vid 17-18 graviditetsveckor och syftet med undersökningen är att datera graviditeten dvs bestämma tiden för beräknad förlossning. Man upptäcker också eventuella tvillingar vid denna undersökning. Redan tidigt visade det sig att visWe studied the prenatal detection rate of various malformations during a study period of 16 years in a population in southern Sweden consisting of 141 240 deliveries. The overall detection rate was 28.4% and the false positive diagnoses were very few. We studied the effect of prenatal diagnosis on the rate of spina bifida in southern Sweden compared with the rest of the country and could show tha

This longitudinal study used a multi-disciplinary approach and examined the relationship between psychosocial and health characteristics and the pattern of informal and formal support for non-institutionalized very old people. The data were derived from a single cohort of 80-year-old people living in Lund, Sweden who were followed over a 3-year period. In order to account for potential sample bias

The efficacy of intraportal (i.p.) nor-epinephrine infusion in controlling bleeding upon liver trauma in the presence of normal as well as defective platelet function was evaluated in the rat. Infusion of nor-epinephrine (10-4 M, NE) took place after cannulation of the gastro-duodenal vein, during 5 min prior to liver trauma. Simultaneously blood pressure (BP) was registered. Platelet aggregation