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Plasminogen and protein PAM: Interactions between streptococcal surface proteins and the human fibrinolytic system
Popular Abstract in Swedish Bakgrund Streptococcus pyogenes, eller grupp A streptokocker, är en av de vanligaste sjukdomsframkallande bakterierna hos människan. De orsakar ofta relativt harmlösa och lättbehandlade ytliga infektioner i hals (halsfluss) och hud (svinkoppor) men kan också ge djupare och livshotande infektioner. Dessutom förekommer följdsjukdomar efter infektioner med grupp A streptoPathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. Group A streptococci of c
Degradation of polyethylene during extrusion. II. Degradation of low-density polyethylene, linear low-density polyethylene, and high-density polyethylene in film extrusion
The degradation of different polyethylenes-low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), and high-density polyethylene (HDPE)-with and without antioxidants and at different oxygen concentrations in the polymer granulates, have been studied in extrusion coating processing. The degradation was followed by online rheometry, size exclusion chromatography, surface oxidation
Factors associated with an increased chance of survival among patients suffering from an out-of-hospital cardiac arrest in a national perspective in Sweden
AiM To describe factors associated with an increased chance of survival among patients suffering from an out-of-hospital cardiac arrest in Sweden. Patients and Methods All patients suffering from an out-of-hospital cardiac arrest, which were not crew witnessed, in Sweden and in,whom cardiopulmonary resuscitation (CPR) was attempted and who were registered in the Swedish Cardiac Arrest Registry. Th
Statistical Modelling of Cell Cycle Dynamics Analysis and Interpretation of BrdUrd DNA FCM-Derived Data
Popular Abstract in Swedish Cancer är en av de vanligaste dödsorsakerna i Sverige idag och att kunna ge cancerpatienter en bättre behandling är därför av stort intresse. En del av detta arbete består av att förbättra förståelsen för hur en cellpopulation, eller då speciellt en cancertumör, växer. Ett medel för att öka kunskapen på området är att använda matematiska modeller. Förmågan att kunna föIt it of great importance to increase the knowledge of various cell cycle kinetic parameters and the objective of this thesis is to use stochastic models to interpret Bromodeoxyuridine (BrdUrd) DNA Flow Cytometry (FCM) derived data in order to estimate such parameters. The cell cycle is the process of growth and division that is essential for an organism to increase in size. The cell cycle consist
Kinetics and mechanism for reduction of halo- and haloam(m)ine platinum(IV) complexes by L-ascorbate
Reduction of the model platinum(IV) complexes cis-[PtCl4(NH3)(2)] (1), trans-[PtCl4(NH3)(2)] (2). trans-[PtCl2(en)(2)](2+) (3), trans-[PtBr2(NH3)(4)](2+) (4), [PtCl6](2-) (5), and [PtBr6](2-) (6) with L-ascorbic acid (H(2)Asc) in 1.0 M aqueous medium at 25 degreesC in the region 1.75 less than or equal to pH less than or equal to 7.20 has been investigated using stopped-flow spectrophotometry. The
Study of spatial and temporal variation of atmospheric optical parameters and their relation with PM 2.5 concentration over Europe using GIS technologies
The purpose of this study was to examine the use of remote sensing aerosol data as an estimator of ground level fine particulate matter concentration (PM 2.5). In order to examine this possible relation, daily MODIS Aerosol Optical Depth (AOD) data were used, collected for an entire year. The analysis involved manipulation of pollution and meteorological data, such as the PM 2.5 concentration wh
Humanitära Interventionens internationella definition - En analys av det kontroversiella undantaget från FN-stadgans allmänna våldsförbud
De mänskliga rättigheterna har blivit allt mer centrala i den internationella rätten. Skyldigheten att upprätthålla dessa rättigheter står ibland mot icke-interventionsprincipen och analysen försvåras av en oenhetlig definition av begreppet. Folkrättsjurister och statspraxis har avgränsat och definierat interventionen olika och denna studie analyserar för dessa. Den här studien fokuserar på folkrHuman rights have become more central to international law. The obligation to maintain these rights are sometimes against the principal of non-intervention. The analysis of the intervention is hampered by different definition of the term. Experts in public international law and state practice has delimited and defined the humanitarian intervention differently and this study analyses these differe
Semantic Analysis of Indoor Floor Plans for Creation of Navigation Graphs
When developing systems for indoor navigation it is important that the user can be led between rooms through doors and openings, and is not told to go through walls. In order to provide this navigation assistance there needs to exist a representation of the indoor environment. One alternative for this is a navigation graph, which—in this thesis—is an undirected graph that connects rooms such that
Chinese International Students’ Everyday National Belonging during the COVID-19 pandemic in France
This thesis explored how French and Chinese national discourses impacted the sense of security of Chinese international students during the COVID-19 pandemic in France. On the one hand, it focused on how the everyday performance and construction of national belonging can offer ontological security to Chinese international students, by providing simple answers to one’s sense of place and self. On t
Straffskärpning i teori och praktik - Om hur skärpningarna av knivlagen kommit att tillämpas i praxis
Den 1 juli 2022 trädde en ändring av lagen (1988:254) om förbud beträffande knivar och andra farliga föremål, även kallad knivlagen, i kraft. Denna innebar bl.a. att kvalifikationsgrunder infördes för bedömningen av om ett brott ska rubriceras som grovt, och att straffskalan för grovt brott skärptes till fängelse i lägst sex månader och högst två år. Syftet med den här uppsatsen är att analyseraOn 1 July 2022, the Swedish Act (1988:254) on the Prohibition of Knives and Other Dangerous Objects (the Swedish Knife Act), which criminalizes possession of knives and other dangerous objects in public places, was amended. Through the amendment, four criteria were introduced to the statutory text, which are to be given particular consideration when assessing whether a violation of the law is to b
Revitalizing Shantou’s “Small Park” district A Livable Historic District with Cultural Heritage in China
This design is located in “Small park historic district”in Shantou, Guangdong Province, China. The site is situated in the coastal area of Southeast China, which has a subtropical climate, humid, hot and rainy, and is a port city. The main forms of transport are ferries, trains, buses and taxis. Shantou is rich in landscape resources, located in an ecological corridor, with many wetlands and park
Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes. a p
Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children RESEARCH ARTICLE Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children Ezio Bonifacio1, Andreas Beyerlein2,3,4, Markus Hippich2,3,4, Christiane Winkler2,3,4, Kendra Vehik5, Michael N. Weedon6, Mic
Den oändliga informationen : Totalbevarande, tillgänglighet och sökbarhet avseende patientjournaler inom Region Skåne
The background to this master´s thesis is a decision by the regional council in Scania, Region Skåne, to preserve all medical records forever. Through the examination of documents and interviews with people associated with the regional archives, and by using Scandinavian institutional theory and time theory, this study looks into how the decision by the regional council is understood and implement
Andelstal i ga-väg för vindkraftverk och vattenkraftverk
Tonkilometermetoden används för beräkning av andelstal för enskilda vägar som är gemensamhetsanläggningar. Den trafikmängd som olika fastighetstyper genererar återspeglas i vissa framtagna schablonvärden. Eftersom det saknas framtagna schablonvärden för specialfastigheter såsom vindkraftverk och vattenkraftverk har jag genom detta examensarbete undersökt möjligheten att ta fram schablonvärden för The ton kilometer method is used to calculate participatory shares for private roads which is joint facility. The amount of traffic that different property types generate is reflected in certain produced templates. Because there are no templates for special properties such as wind turbines and hydroelectric plants I have investigated if it is possible to produce these types of values. I have also
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https://www.staff.lu.se/sites/staff.lu.se/files/2022-12/Projektplansmall.docx - 2026-05-19
DNA-Sequencing Platform Based on Light-Guiding Nanowires
From Strands to Wires All the genetic information required to develop and maintain an organism is packed tightly into the molecule known as DNA. Determining the order of the four bases, which are the building blocks of DNA, enables the identification of a DNA segment. Modern disease diagnostics use this identification method, known as DNA sequencing, to inspect genetic integrity. Thus, it is vita
Möten över generationer - Att implementera ett program inriktat på sociala möten mellan barn och äldre i befintlig byggd miljö
Detta examensarbete introducerar ett nytt förslag på användning av nedlagda skolor, fabrikslokaler, vårdinstitutioner, och andra övergivna anläggningar som står tomma runt om på Sveriges landsbygd. Behovet av funktioner dessa byggnader en gång var ämnade för saknar idag efterfrågan och jag vill lyfta potentialen sådana platser kan ha för särskilda användningsområden, i jämförelse med att bygga nytThis thesis introduces a new proposal for the reuse of abandoned schools, industrial buildings, care institutions, and other vacant facilities scattered across rural Sweden. The functions these buildings once served are no longer in use, and I aim to highlight the potential these places may hold for specific new uses, as an alternative to constructing new buildings. With consideration of a current
Following the Path of Individual Beam Electrons through LDMX
När orden mörk materia nämns förs tankarna hos många till sci-fi böcker eller serietidningar. Kanske föreställer man sig en främmande substans i en provrör, eller ett destruktivt svart hål. Sanningen är att mörk materia är mycket mindre dramatiskt än så. Ett definierande drag hos mörk materia är att det interagerar ytterst svagt med vanlig materia. Troligen passerar mörk materiepartiklar rakt igenThe Light Dark Matter Experiment (LDMX) is a fixed-target missing-momentum experiment which hopes to detect dark matter in the MeV-GeV mass range. This is done by firing an 8 GeV electron beam at a thin tungsten target, where the electrons produce dark matter through a process called dark bremsstrahlung. Electrons which have gone through dark matter production can then be found by looking for miss
När får arbetsgivare omplacera arbetstagare? - En undersökning av arbetsgivares och arbetstagares rättigheter respektive skyldigheter i två omplaceringssituationer inom privat sektor
Inom det svenska arbetsrättsliga systemet finns det huvudsakligen två typer av omplaceringssituationer. Den första är att arbetsgivare i kraft av sin arbetsledningsrätt kan omplacera arbetstagare inom ramen för deras arbetsskyldighet. Det kan ske utan att det finns någon nära förestående risk för uppsägning. Den andra är att arbetsgivare, enligt 7 § 2 stycket lagen (1982:80) om anställningsskydd, Within the Swedish labor law system, there are mainly two types of relocation situations. The first is that employers, by virtue of their management right, can relocate employees within the framework of their work obligation. This can be done without any imminent risk of termination of employment. The second is that employers, according to Section 7 Part 2 of the Employment Protection Act (1982:80
