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Mutual Learning Exercise : MLE on Innovation-related Procurement

This Mutual Learning Exercise (MLE) on Innovation-related Procurement was conducted under the Horizon 2020 Policy Support Facility run by the European Commission’s Directorate-General for Research and Innovation. The 15 countries that participated were: Austria, Belgium - Brussels Region, Estonia, France, Germany, Greece, Latvia, Lithuania, Netherlands, Norway, Portugal, Slovenia, Spain, Sweden an

Microclimate and Thermal Comfort of Urban Spaces in Hot Dry Damascus- Influence of urban design and planning regulations

The aim of this study is to develop better understanding of the relationship between microclimate and urban design in the hot dry city of Damascus. This is done by studying the impact of urban regulations on microclimate in different urban design patterns in modern Damascus. This study also investigates the behaviour of different thermal comfort indices to define the thermal comfort and acceptabil

Filter Plate–Based Screening of MIP SPE Materials for Capture of the Biomarker Pro-Gastrin-Releasing Peptide

Affinity-based solid-phase extraction (SPE) is an attractive low-cost sample preparation strategy for biomarker analysis. Molecularly imprinted polymers (MIPs) as affinity sorbents offer unique opportunities for affinity SPE, due to their low manufacturing cost and high robustness. A limitation is the prediction of their affinity; therefore, screening of analyte recovery and specificity within a l

Partitioning of peptides and recombinant protein-peptide fusions in thermoseparating aqueous two-phase systems: effect of peptide primary structure

Genetic engineering has been used for fusion of peptides, with different length and composition, on a protein to study the effect on partitioning in an aqueous two-phase system. The system was composed of dextran and the thermoseparating ethylene oxide-propylene oxide random copolymer, EO30PO70. Peptides containing tryptophan, proline, arginine or aspartate residues were fused at the C-terminus of

VIP potentiates cholinergic effects on the mucociliary system in the maxillary sinus

The neuropeptide vasoactive intestinal polypeptide (VIP), which is found in a population of cholinergic parasympathetic neurons in the airways, has no effects per se on mucociliary activity. In order to test the hypothesis that VIP may modulate cholinergic regulation of the mucociliary system, VIP was infused intraarterially (8.4 pmol/kg/min), and the response to challenges with methacholine in th

Design and measurement of a CT delta-sigma ADC with switched-capacitor switched-resistor feedback

The performance of traditional continuous-time (CT) delta-sigma analog-to-digital converters (ADCs) is limited by their large sensitivity to feedback pulse-width variations caused by clock jitter in their feedback digital-to-analog converters (DACs). To mitigate that effect, we propose a modified switched-capacitor (SC) feedback DAC technique, with a variable switched series resistor (SR). The arc

Intrinsic femtosecond charge generation dynamics in single crystal CH3NH3PbI3

Hybrid metal-organic perovskite solar cells have astounded the solar cell community with their rapid rise in efficiency while maintaining low-cost fabrication. The intrinsic material photophysics related to the generation of free charges, their dynamics and efficiency, however, remains to be understood. As fabrication techniques improve, larger crystal grain sizes have been shown to be a critical

Heterogeneous nuclear ribonucleoprotein C proteins interact with the human papillomavirus type 16 (HPV16) early 3'-untranslated region and alleviate suppression of HPV16 late L1 mRNA splicing.

In order to identify cellular factors that regulate human papillomavirus type 16 (HPV16) gene expression, cervical cancer cells permissive for HPV16 late gene expression were identified and characterized. These cells either contained a novel spliced variant of the L1 mRNAs that bypassed the suppressed HPV16 late, 5'-splice site SD3632, produced elevated levels of RNA-binding proteins SRSF1 (ASF/SF

Quality of life and toxicity in breast cancer patients using adjuvant TAC (docetaxel, doxorubicin, cyclophosphamide), in comparison with FAC (doxorubicin, cyclophosphamide, 5-fluorouracil).

Abstract in UndeterminedThe aim of this study was to compare two regimens of chemotherapy in patients with breast cancer, including FAC (doxorubicin, cyclophosphamide, and 5-fluorouracil) and TAC (docetaxel, doxorubicin and cyclophosphamide); and analyze the toxicity of these treatments and observe patient's health-related quality of life.Health-related quality of life was assessed for up to 4 mon

Calculation of geomagnetically induced currents in the 400 kV power grid in southern Sweden

Sweden has experienced many geomagnetically induced current (GIC) events in the past, which is obviously due to the high-latitude location of the country. The largest GIC, almost 300 A, was measured in southern Sweden in the earthing lead of a 400 kV transformer neutral during the magnetic storm on 6 April 2000. On 30 October 2003, the city of Malmo at the southern coast suffered from a power blac

Space weather events in July 1982 and October 2003 and the effects of geomagnetically induced currents on Swedish technical systems

In this paper, we analyse in detail two famous space weather events; a railway problem on 13-14 July 1982 and a power blackout on 30 October 2003. Both occurred in Sweden during very intensive space weather storms and each of them a few years after the sunspot maximum. This paper provides a description of the conditions on the Sun and in the solar wind leading to the two GIC events on the ground.

Theoretical study of the unusual potential energy curve of the A (1)Sigma(+) state of AgH

The A (1)Sigma(+) potential energy curve of AgH is studied by means of the second-order multistate multireference perturbation theory including the spin-orbit and relativistic effects. The anomalous behavior of the vibrational energy levels observed in experiment is reproduced well by theory. An analysis of the A (1)Sigma(+) wave function shows that at the internuclear distance of 4-6 Angstrom, a

What is ideal genetic counselling? A survey of current international guidelines

The objective of this article is to review guidelines that address counselling in the context of genetic testing in order to summarise what aspects of counselling they consider most important, and to examine how they construct the ideal of genetic counselling. Guidelines were collected by examining the websites of different international professional, political, ethical and patient organisations,

Labour Productivity in the Building Industry – Studies of Uganda

Research has been pointing out that productivity in the building industry is stagnant and in some cases declining. Poor productivity of craftsmen is one of the causes of cost and time overruns on building projects. Productivity of labour is particularly important especially in developing countries where most of the building work is still carried out on manual basis. The objective of this research

An automatic method for quantification of myocardium at risk from myocardial perfusion SPECT in patients with acute coronary occlusion.

BACKGROUND: In order to determine myocardial salvage, accurate quantification of myocardium at risk (MaR) is necessary. We present a validated novel automatic segmentation algorithm for quantification of MaR by myocardial perfusion SPECT (MPS) in patients with acute coronary occlusion. METHODS AND RESULTS: Twenty-nine patients with coronary occlusion were injected with a perfusion tracer before re

Geographic Distribution of Intra-specific Variation in Widespread Eurasian boreo-nemoral Woodland Herbs

Popular Abstract in Swedish Geografisk fördelning av inomartsvariation i vittspridda Euroasiska skogsväxter Torbjörn Tyler Sammanfattning av författaren's doktorsavhandling Inledning Arter's utbredningar bestäm's inte bara av omvärldsfaktorer som klimat och jordmån utan även av de möjligheter det givit's dem att sprida sig. För att sprida sig över stora geografiska områden kräv's tid och i en väMany woodland plant species have huge distribution areas covering large parts of the Eurasian continent including areas that were glaciated during the last glacial period. In the present thesis, the geographic distribution of variation within such species is investigated and discussed in relation to glacial survival and post-glacial migration, dispersal ability, breeding system and levels of gene-

Correlates of Nine-Month Retention following Interim Buprenorphine-Naloxone Treatment in Opioid Dependence: A Pilot Study.

Interim medication-only treatment has been suggested for the initiation of opioid maintenance treatment (OMT) in opioid-dependent subjects, but this rarely has been studied using buprenorphine instead of methadone. Following a pilot trial assessing interim buprenorphine-naloxone treatment in order to facilitate transfer into OMT, we here aimed to study retention, and potential correlates of retent

Bleeding peptic ulcer - time trends in incidence, treatment and mortality in Sweden.

Abstract Background: The incidence of peptic ulcer disease was expected to decrease following the introduction of acid inhibitors and H. pylori eradication. Aim: This study analyses possible changes in the incidence of bleeding peptic ulcer, treatment and mortality over time. Methods: Residents of Malmö hospitalised for bleeding gastric or duodenal ulcer disease1987-2004 were identified in hospita