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Background: Healthcare systems across the globe face challenges with staffing shortages and unsustainable expenditure, intensified by an aging population requiring more long-term care. Mixed home care, combining formal and informal care at home, is a growing market, where Internet of Medical Things (IoMT) solutions offer opportunities for efficiency and personalized care. Purpose: To identify, un
Since its composition two centuries ago in 1824, Beethoven’s Ninth Symphony (Ode to Joy) has been heralded the world over not only as a great work of art, but also as a symbol of political importance. In Germany, it was lionised as the embodiment of a national spirit, first during the Franco-Prussian war, then as a prize of the Nazi repertoire; in Rhodesia, it became the national anthem of a far-r
Klimatförändringar orsakade av antropogena faktorer har en ökande effekt på både naturliga och humana system. Klimatförändringar bidrar till en förändring av varaktigheten, frekvensen och intensiteten av extrema väderhändelser (som till exempel stormar, översvämningar och värmeböljor). Några exempel på konsekvenser från klimatförändringar på de humana systemen är förlust av liv, förlust av egendomThe changing climate caused by anthropogenic factors has an increasing effect on natural and human systems. There is therefore an increasing need for society to adapt to the effects of climate change (IPCC, 2012; Rescalvo et al., 2013) This is vital since the effects of climate change are already being noticed in many parts of the world (Rescalvo et al., 2013). However, municipalities in Sweden ge
Objective: Systemic lupus erythematosus (SLE) is a complex multi-organ disease, characterised by relapses and remissions. Designing a high-quality randomised controlled trial poses many challenges. We have developed evidenced-based recommendations for points to consider in conducting clinical trials in patients with SLE. Methods: The EULAR Task Force on SLE comprised 19 specialists and a clinical
Methanol oxidation to formaldehyde was studied over a series of Fe-Mo-O catalysts with various Mo/Fe atomic ratio and the end compositions Fe2O3 and MoO3. The activity data shows that the specific activity passes through a maximum with increase of the Mo content and is the highest for Fe2(MoO4)3. The selectivity to formaldehyde, on the other hand, increases with the Mo content in the catalyst. A s
The use of longitudinal historical micro-level demographic data for research presents many challenges. The Intermediate Data Structure (IDS) was developed to try to solve some of these challenges by facilitating the storing and sharing of such data. This article proposes an extension to the IDS, which allows the standardization and storage of constructed variables. It also describes how to produce
The potential of Fe-V-oxide catalysts for use in methanol oxidation is explored. Our results show that although FeVO4 is active and selective for formaldehyde formation, it is not completely stable towards volatilization under reaction conditions. Attempts to stabilize Fe-V-oxide were made using titania, alumina and silica supports. However, we observe that although some stabilization is achieved
Housing expenditure is without doubt one of the biggest expenditure posts for all households. By using econometrics to estimate regressions with cross-‐sectional data including more than 1500 individuals, this thesis examines whether there is any individual characteristics that determines how big a share of the disposable income that is spent on housing each month. The results indicate that diffe
Glucagon receptor (Gcgr) signaling maintains hepatic glucose production during the fasting state; however, the importance of the Gcgr for lipid metabolism is unclear. We show here that fasted Gcgr-/- mice exhibit a significant increase in hepatic triglyceride secretion and fasting increases fatty acid oxidation (FAO) in wild-type (WT) but not in Gcgr-/- mice. Moreover fasting upregulated the expre
We derive short-distance constraints for the hadronic light-by-light contribution (HLbL) to the anomalous magnetic moment of the muon in the kinematic region where the three virtual momenta are all large. We include the external soft photon via an external field leading to a well-defined Operator Product Expansion. We establish that the perturbative quark loop gives the leading contribution in a w
Intermodality or combining more than one transport mode during a single trip has been put forward to facilitate a modal shift from private car to more environmentally friendly modes such as public transport, cycling or walking. Bike-and-ride – that is, integrating cycling and public transport in one trip – is an attractive combination, as cycling as an active and clean mode is faster than walking
Agricultural soils contribute to human welfare through their generation of manifold ecosystem services such as food security, water quality and climate regulation, but these are degraded by common farming practices. We have developed a roadmap for evaluating the contribution of both private- and public-good ecosystem services generated by agricultural soils to societal welfare. The approach consid
The procedure of aligning a positron emission tomography (PET) image with a common coordinate system, spatial normalization, typically demands a corresponding structural magnetic resonance (MR) image. However, MR imaging is not always available or feasible for the subject, which calls for enabling spatial normalization without MR, MR-less spatial normalization. In this work, we propose a template-
Firefighters can be occupationally exposed to a wide range of airborne pollutants during fire-extinguishing operations. The overall study aim was to characterize occupational exposure to smoke for several groups of workers responding to fires, with specific aims to determine the correlations between exposure markers and to biologically assess their systemic exposure to polycyclic aromatic hydrocar
Modeling metalloproteins often requires classical molecular dynamics (MD) simulations in order to capture their relevant motions, which in turn necessitates reliable descriptions of the metal centers involved. One of the most successful approaches to date is provided by the "cationic dummy model", where the positive charge of the metal ion is transferred toward dummy particles that are bonded to t
Therapies derived from substances of human origin (SoHOs) such as organs, cells, and tissues provide life-saving or life-changing treatment for millions of people worldwide each year. However, many people lack timely access to SoHO-based therapies because of insufficient supplies of these exceptional health resources and/or broader barriers in access to healthcare. Despite well-established governm
Objectives: Endovascular repair (ER) of popliteal artery aneurysm (PAA) is an alternative to open repair. However, there is no standardized protocol for when to opt for ER and the decision is therefore at the discretion of the clinician. This study aims to evaluate the adherence to the Instruction For Use (IFU) in patients undergoing ER for PAA and factors associated with stent graft patency at on
The aim of this technical note is to present methods that allow for direct computation of the bed roughness due to sediment transport based on a formula developed in the literature for cases involving current or waves separately. The methods result in approximate nondimensional expressions for the exact solutions in terms of polynomials determined by least-square fits, where the accuracy of the po
