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Functional dissection of the gene regulatory mechanism underlying variation in blood CD34+ cell levels at 1p36.23/ENO1

Understanding the genetic regulation of blood CD34+ cell levels could lead to better methods for stem cell mobilization and transplantation. Recently, in a genome-wide association study (GWAS), we identified 11 genetic associations with blood CD34+ cell levels. One of the most significant maps to an intergenic region between the ENO1 and RERE genes at chromosome 1p36.23. However, the underlying me

A Novel Approach to Economic Evaluation of Infrastructure? Examining the Benefit Analyses in the Swedish High-Speed Rail Project

The purpose of this paper is to describe a novel approach to economic evaluation of infrastructure, the benefit analyses in the Swedish high-speed rail project, and to analyse what role these can play in the decision-making process. The reports identify benefits from infrastructure investment at the local level and were intended to assist in making co-financing agreements and as a basis for decisi

Introduction : Into the fields of stubborn obstacles and lingering exclusion

Accessibility today has a contradictory character. One the one hand, people with disabilities are welcomed and included, with ambitious promises in policies and declarations. On the other hand, they are still excluded in everyday practices. This volume explores this contradiction in three areas: city and transport, knowledge and education, and law, institutions and history. Sweden is the primary cAccessibility today has a contradictory character. One the one hand, people with disabilities are welcomed and included, with ambitious promises in policies and declarations. On the other hand, they are still excluded in everyday practices. This volume explores this contradiction in three areas: city and transport, knowledge and education, and law, institutions and history. Sweden is the primary c

Kala-azar outbreak in Libo Kemkem, Ethiopia : epidemiologic and parasitologic assessment

In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemkem, Ethiopia. In October 2005, a rapid assessment was conducted using data from 492 patients with VL treated in the district health center and a household survey of 584 residents of four villages. One subdistrict accounted for 71% of early cases, but the incidence and number of affected subdistricts increased pr

Får jag lov att bygga min solcellsanläggning här? - En studie av miljöbalkens krav på solcellsanläggningar på jordbruksmark och förutsättningarna för solsambruk.

I takt med allt mer omfattande globala klimatförändringar växer behovet av förnybara energikällor, såsom solenergi. Det har därför blivit allt vanligare att entreprenörer väljer att ansöka om att få anlägga solcellsparker på jordbruksmark. Förfarandet för en sådan prövning bedöms utifrån 3 kap 4 § miljöbalken och är rättsligt komplicerat. Dessutom ska miljöbalkens övergripande mål om hållbar utvecAs global warming gradually increases, the need for renewable energy sources is growing rapidly. One such energy source is solar energy. It has therefore become more common for entrepreneurs to apply for permission to construct solar parks on larger open areas, such as agricultural land. The assessment is dictated by Chapter 3, Section 4 of the Swedish Environmental Code. However, the procedure fo

Guidelines-on-handling-complaints-from-students-concerning-first-second-and-third-cycle-studies-at-L

Guidelines on Handling Complaints from Students Concerning First, Second and Third-Cycle Studies at Lund University Page 1 of 6 Vice-Chancellor DECISION Reg. no STYR 2023/1355 Date 22 June 2023 Guidelines on Handling Complaints from Students Concerning First, Second and Third-Cycle Studies at Lund University Background According to the Standards and Guidelines for Quality Assurance in the European

https://www.staff.lu.se/sites/staff.lu.se/files/2023-08/guidelines-on-handling-complaints-from-students-concerning-first-second-and-third-cycle-studies-at-LU%20.pdf - 2026-05-25

Kurslitteratur mven17

Kurslitteratur MVEN17, Samhällsplanering i klimatperspektiv, VT2017 Planering som styrmedel (Vecka 3 samhällsplanering i klimatperspektiv) Boverket, (2010) Planer som styrmedel för att minska samhällets klimatpåverkan, Boverket (92 sidor) (finns tillgänglig online) Davidse, B. J., Othengrafen, M. & Deppisch, S. (2015) Spatial planning practices of adapting to climate change. Refereed Article No. 5

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/kurslitteratur_mven17.pdf - 2026-05-25

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DC230036_proof.pdf Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5–15-Year-Old Children Followed in the TEDDY Study Xiang Liu, Suzanne Bennett Johnson, Kristian F. Lynch, Kerry Cordan, Russell Pate, Martha D. Butterworth, Åke Lernmark, William A. Hagopian, Marian J. Rewers, Richard A. McIndoe, Jorma Toppari, Anette-G. Ziegler, Beena Akolkar, Jeffrey P. Krischer

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-11/150_2.pdf - 2026-05-25

Sphingolipid hydrolysis enzymes in the gastrointestinal tract

In the intestinal tract, there are enzymes that hydrolyze both endogenous and exogenous sphingolipids. The alkaline sphingomyelinases (SMase) of the gut and human bile have been most studied, and a major part of this chapter discusses these enzymes. It also discusses studies of ceramidase, glycosylceramidase, and the digestion of dietary sphingolipids. In the intestinal tract, a distinct enzyme th

Malin Espersson (ISM) - Pedagogisk Portfölj

Pedagogisk portfölj PEDAGOGISK PORTFÖLJ Malin Espersson malin.espersson@ism.lu.se 1 Innehållsförteckning Introduktion ............................................................................................................................................ 2 Pedagogisk biografi .......................................................................................................................

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2023-05/Malin%20Espersson%20(ISM)%20-%20Pedagogisk%20portf%C3%B6lj.pdf - 2026-05-25

The equilibrium structure of trans-glyoxal from experimental rotational constants and calculated vibration-rotation interaction constants

A total of six high-resolution FT-IR spectra for trans-glyoxal-d(2), trans-glyoxal-d(1) and trans-glyoxal-C-13(2) were recorded with a resolution ranging from 0.003 to 0.004 cm(-1). By means of a simultaneous ground state combination difference analysis for each of these isotopologues using the Watson Hamiltonian in A-reduction and I-r-representation the ground state rotational constants are obtai

N1421K mutation in the glycoprotein Ib binding domain impairs ristocetin- and botrocetin-mediated binding of von Willebrand factor to platelets.

von Willebrand disease (VWD) is a common inheritable bleeding disorder caused by deficiency of von Willebrand Factor (VWF), which is involved in platelet adhesion and aggregation. We report a family consisting of three patients with VWD characterized by an apparently normal multimeric pattern, moderately decreased plasma factor VIII (FVIII) and VWF levels, and disproportionately low plasma VWF:RCo

Characterization of Membrane Proteins: From a gated plant aquaporin to animal ion channel receptors

Membrane proteins play several important roles in a cell. Among these proteins are aquaporins (AQPs) and transient receptor potential (TRP) ion channels that mediate water transport, temperature and noxious chemical sensation, respectively. The function of some AQPs, for example the spinach isoform SoPIP2;1 is regulated by pH, phosphorylation and heavy metals such as mercury. However, the mechanis

Accounting and auditing in municipal organisations – Four papers on accounting compliance and audit costs

This thesis is a quantitative study of accounting compliance and audit costs in Swedish municipal organisations, consisting of four papers. Three of the papers explore factors that explain accounting compliance concerning financial reporting and revenue recognition in Swedish municipal water, sewerage and solid waste management organisations. The fourth paper explores the determinants of professio

Geothermal ecosystems as natural climate change experiments : The ForHot research site in Iceland as a case study

This article describes how natural geothermal soil temperature gradients in Iceland have been used to study terrestrial ecosystem responses to soil warming. The experimental approach was evaluated at three study sites in southern Iceland one grassland site that has been warm for at least 50 years (GO), and another comparable grassland site (GN) and a Sitka spruce plantation (FN) site that have bot

Palladium(II) Halide Complexes II. Acid Hydrolysis and Halide Anations of Palladium(II) Chloro and Bromo Aqua Complexes

The rate constants for the chloride and bromide anations of Pd(H2O)42+, the chloride anations of PdCl3H2O−, the bromide anation of PdBr3H2O− and the acid hydrolysis of PdCl(H2O)3+, PdBr(H2O)3+, PdCl42−, and PdBr42− have been determined at 15, 25 and 35 °C using a stopped-flow technique. The ionic strength was 1.00 M and the supporting electrolyte perchloric acid. The obtained rate constants and thThe rate constants for the chloride and bromide anations of Pd(H2O)42+, the chloride anations of PdCl3H2O−, the bromide anation of PdBr3H2O− and the acid hydrolysis of PdCl(H2O)3+, PdBr(H2O)3+, PdCl42−, and PdBr42− have been determined at 15, 25 and 35 °C using a stopped-flow technique. The ionic strength was 1.00 M and the supporting electrolyte perchloric acid. The obtained rate constants and th

A breakpoint map of recurrent chromosomal rearrangements in human neoplasia

Cytogenetic studies over the past few decades have revealed clonal chromosomal aberrations in almost 27,000 human neoplasms. Many of these neoplasia-associated chromosomal abnormalities have been characterised at the molecular level, revealing previously unknown genes that are closely associated with the tumorigenic process. Information on chromosome changes in neoplasia is growing rapidly, making