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Prolonged Fatigue and Mental Health Challenges in Critical COVID-19 Survivors

Background: The aim of this study was to investigate the development of fatigue and mental illness between 3 and 12 months after critical COVID-19 and explore risk factors for long-lasting symptoms. Study Design and Methods: A prospective, multicenter COVID-19 study in southern Sweden, including adult patients (≥18 years) with rtPCR-confirmed COVID-19 requiring intensive care. Survivors were invi

Multicentre Experience with Novel Bidirectional Double Cuffed Inner Branches for Complex Endovascular Aortic Repair

Objective: This study aimed to report the initial experience with a novel bidirectional double cuff inner branch design for incorporation of renal and mesenteric arteries in patients undergoing fenestrated and branched endovascular aortic repair (F/BEVAR). Methods: A retrospective review was undertaken of the experience of F/BEVAR with grafts integrating at least one bidirectional double cuffed in

Midwives’ experiences of professional learning when practicing collegial midwifery assistance during the active second stage of labour : data from the oneplus trial

Background: Learning is a lifelong process and the workplace is an essential arena for professional learning. Workplace learning is particularly relevant for midwives as essential knowledge and skills are gained through clinical work. A clinical practice known as ‘Collegial Midwifery Assistance’ (CMA), which involves two midwives being present during the active second stage of labour, was found to

Postnatal intervention for the treatment of FNAIT : a systematic review

Objective: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is associated with life-threatening bleeding. This systematic review of postnatal management of FNAIT examined transfusion of human platelet antigen (HPA) selected or unselected platelets, and/or IVIg on platelet increments, hemorrhage and mortality. Study design: MEDLINE, EMBASE and Cochrane searches were conducted until 11 May 20

Patients’ experiences of using the Integrated Palliative care Outcome Scale for a person-centered care : A qualitative study in the specialized palliative home-care context

The aim of this study was to explore patients’ experiences of using the Integrated Palliative care Outcome Scale (IPOS) during specialized palliative home care. The study adopted a qualitative approach with an interpretive descriptive design. Interviews were performed with 10 patients, of whom a majority were diagnosed with incurable cancer. Our findings suggest that the use of IPOS as a basis for

Mapping of domestic hot water circulation losses in buildings – results from 134 measurements

The hot water circulation system in a building is a system which helps prevent Legionella problems whilst ensuring that tenants have access to hot water quickly. Poorly designed or implemented systems not only increase the risk to people’s health and thermal comfort, but even result in an increase in the energy needed for this system to function properly. Results from previous studies showed that

Rethinking regional embeddedness and innovation systems for transitions towards just, responsible, and circular bioeconomies

Few studies have explicitly explored regional embeddedness and both the inconsistencies and injustices of circular bioeconomy (CBE) innovations. To better navigate the normative dimension of these innovations and CBE transitions in general, our article presents a threefold argument for the relevance of the regional level of analysis. First, CBE innovations are influenced by and affect regional met

Diclofenac for acute postoperative pain in children

Background: Many children undergo various surgeries, which often lead to acute postoperative pain. This pain influences recovery and quality of life. Non-steroidal anti-inflammatory drugs (NSAIDs), specifically cyclo-oxygenase (COX) inhibitors such as diclofenac, can be used to treat pain and reduce inflammation. There is uncertainty regarding diclofenac's benefits and harms compared to placebo or

Gravitoviscous protoplanetary disks with a dust component : III. Evolution of gas, dust, and pebbles

Aims. We study the dynamics and growth of dust particles in circumstellar disks of different masses that are prone to gravitational instability during the critical first Myr of their evolution. Methods. We solved the hydrodynamics equations for a self-gravitating and viscous circumstellar disk in a thin-disk limit using the FEOSAD numerical hydrodynamics code. The dust component is made up of two

Development of Circularly Recyclable Low Melting Temperature Bicomponent Fibers toward a Sustainable Nonwoven Application

Sustainable low melting temperature bicomponent polyester fibers that can be circularly recycled were developed. The potentially biobased poly(hexamethylene terephthalate) (PHT), acting as the low melting temperature sheath material in the designed bicomponent fibers, was synthesized in a pilot scale. The obtained PHT with an intrinsic viscosity of 0.47 dL/g showed suitable processability when it

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a genome-wide association study with 53,400 cases and 433,201 controls and replicated si

The augmentation of internal tip heat transfer in gas turbine blades using a pair of delta-winglet vortex generators

A novel method to enhance the heat transfer on the internal tip surface of gas turbine blades was developed. Effects of delta-winglet vortex generators (DWVG) and their angle of attack on the vortical structures and mechanism of enhanced heat transfer were investigated. Seven different angles of attack were considered: 0°, 15°, 30°, 45°, 60°, 75°, and 90°. The Reynolds number varies from 10,000 to

Population heterogeneity in associations between hormonal contraception and antidepressant use in Sweden : a prospective cohort study applying intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA)

OBJECTIVES: From a reproductive justice framework, we aimed to investigate how a possible association between hormonal contraceptive (HC) and antidepressants use (as a proxy for depression) is distributed across intersectional strata in the population. We aimed to visualise how intersecting power dynamics may operate in combination with HC use to increase or decrease subsequent use of antidepressa

Optimisation of the resource efficiency of food manufacturing via the Internet of Things

The food sector is currently very inefficient due to a large amount of food waste it generates, and the volumes of water and energy used. This problem is aggravated by increasing economic costs and stricter regulations associated with the disposal and treatment of food waste, carbon emissions and wastewater discharge. Because of this, resource efficiency is key to a sustainable food system. In thi

The changing arguments for assigning non-organised volunteers as assistant supervisors in the Swedish prison and probation service

This study explores the ideas behind and development of assigning non-organised volunteers as assistant supervisors within the Swedish Prison and Probation Service. The Swedish way of collaborating with volunteers in supervision of offenders is unique in an international perspective. This article includes an international literature review for this area that seldom is studied. With the help of Cha

Challenges resulting from urban density and climate change for the EU energy transition

Dense urban morphologies further amplify extreme climate events due to the urban heat island phenomenon, rendering cities more vulnerable to extreme climate events. Here we develop a modelling framework using multi-scale climate and energy system models to assess the compound impact of future climate variations and urban densification on renewable energy integration for 18 European cities. We obse

On catalytic preorganization in oxyanion holes : highlighting the problems with the gas-phase modeling of oxyanion holes and illustrating the need for complete enzyme models

Oxyanion holes play a major role in catalyzing enzymatic reactions, yet the corresponding energetics is frequently misunderstood. The main problem may be associated with the nontrivial nature of the electrostatic preorganization effect, without following the relevant formulation. That is, although the energetics of oxyanion holes have been fully quantified in early studies (which include both the

The fundamentals of eye tracking part 1 : The link between theory and research question

Eye tracking technology has become increasingly prevalent in scientific research, offering unique insights into oculomotor and cognitive processes. The present article explores the relationship between scientific theory, the research question, and the use of eye-tracking technology. It aims to guide readers in determining if eye tracking is suitable for their studies and how to formulate relevant

Deficiency of Peptidylglycine-alpha-amidating Monooxygenase, a Cause of Sarcopenic Diabetes Mellitus

Context: Peptidylglycine-α-amidating monooxygenase (PAM) is a critical enzyme in the endocrine system responsible for activation, by amidation, of bioactive peptides. Objective: To define the clinical phenotype of carriers of genetic mutations associated with impaired PAM-amidating activity (PAM-AMA). Design: We used genetic and phenotypic data from cohort studies: the Malmö Diet and Cancer (MDC;