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Aim/hypothesis: Human enteroviral infections are suggested to be associated with type 1 diabetes. However, the mechanism by which enteroviruses can trigger disease remains unknown. The present study aims to investigate the impact of enterovirus on autophagy, a cellular process that regulates beta cell homeostasis, using the clonal beta cell line INS(832/13) and human islet cells as in vitro models

Cementproduktion står idag för en ansenlig andel av världens koldioxidutsläpp, vilket driver utvecklingen av bindemedel med lägre koldioxidutsläpp. För utsläppen i ett längre perspektiv är dock de nya bindemedlens beständighet absolut avgörande. De flesta nedbrytningsmekanismer är direkt relaterade till både fukt- och jontransport. Dessa processer har undersökts i många studier, men huvudsakligen Cement production is responsible for a significant portion of manmade CO2 emissions. This motivates the development of cementitious binders with a lower carbon footprint. Considering the emissions in a longer perspective, the durability of concrete structures is absolutely essential. Most degradation of concrete structures is closely related to both moisture transport and ion transport. Many studi

The overall aim of this thesis was to study life satisfaction (LS) and factors associated to LS in the group aged 78 and above. As an aid in interpreting the findings, Baltes’ and Baltes’ theory of selective optimisation with compensation (SOC) was used. All four studies included the same studypopulation who were followed for three years in the study Good Aging in Skåne, a national, randomized, po

Social anxiety disorder (social phobia) is a debilitating and common anxiety disorder, with a lifetime prevalence ranging from 6 % to 12 %. The condition has its onset in childhood and early adolescence, affects females more often than males, and if untreated is associated with high risk of developing comorbid anxiety and mood disorders, as well as substance abuse. The increasingly growing body of

Popular Abstract in Swedish Ökad förståelse för hjärtats pumpfunktion är av stort intresse för att kunna förbättra diagnostik, behandling och prognoser för hjärtsjuka patienter. Blodflöde i hjärtat är direkt kopplat till hjärtats form och rörelse och kan därför vara en viktig markör för hjärtats funktion. Därför var målet med denna avhandling att utveckla och förbättra mätningar av blodflöde med hIncreased understanding of the pumping mechanics of the heart are of great importance to develop diagnostics, treatment and prognostics for cardiovascular diseases. Blood flow in the heart is connected to its anatomy and function, and may therefore be a sensitive marker of cardiac health and disease. Therefore, the aim of this thesis is to develop and validate methods for quantification and visual

Popular Abstract in Swedish Proteoglykaner (PG), framför allt sådana som bär glykosaminoglykan-sidokedjor av heparansulfat (HS) typ, utgör multifunktionella receptorer på cellytan och i pericellulär matrix hos alla adherenta celler i högre organismer. HS-proteoglykaner är inblandade i många olika cellprocesser, bl.a. koagulation, celltillväxt, och aktivering av enzymer, antienzymer samt bindning t

Background Today many organizations convert from being a traditional functional organization to becoming more temporary project-based organizations in order to respond to the changing environment. As a result, project-based organizations have difficulties to learn from within the project and between projects which force project members to “reinvent the wheel” over and over again. If organizations

Purpose: The purpose of this study is to explore how brand managers align their brand identity within online brand communities where the communication is shared in order to create a reinforcing point of contact instead of a source of mixed messages. Problem: With the increasing usage of the internet, brand managers are today forced and challenged to align and re-enforce a brand’s identity online w

Denna uppsats baserar sig på en utredning av Försäkringskassan, som presenterades i maj 2005. Titeln var Utredning om könsneutralt och delat barnbidrag. Försäkringskassan hade fått i uppdrag av regeringen att utreda förutsättningarna för att göra lagstiftningen kring barnbidraget könsneutral och införa en möjlighet för föräldrarna att kunna dela bidraget mellan sig. Den nuvarande barnbidragslagsti

A total of 16 global chemistry transport models and general circulation models have participated in this study; 14 models have been evaluated with regard to their ability to reproduce the near-surface observed number concentration of aerosol particles and cloud condensation nuclei (CCN), as well as derived cloud droplet number concentration (CDNC). Model results for the period 2011-2015 are compar

IMPORTANCE: Correct diagnosis of ovarian cancer results in better prognosis. Adnexal lesions can be stratified into the Ovarian-Adnexal Reporting and Data System (O-RADS) risk of malignancy categories with either the O-RADS lexicon, proposed by the American College of Radiology, or the International Ovarian Tumor Analysis (IOTA) 2-step strategy.OBJECTIVE: To investigate the diagnostic performance

Background: Intraventricular haemorrhage (IVH) is a major complication of preterm birth. Large haemorrhages are associated with a high risk of disability and hydrocephalus. Instability of blood pressure and cerebral blood in the newborn flow are postulated as causative factors. Another mechanism may involve reperfusion damage from oxygen free radicals. It has been suggested that phenobarbital stab

Background: Snacking is a common diet behaviour which accounts for a large proportion of daily energy intake, making it a key determinant of diet quality. However, the relationship between snacking frequency, quality and timing with cardiometabolic health remains unclear. Design: Demography, diet, health (fasting and postprandial cardiometabolic blood and anthropometrics markers) and stool metagen

Diabetic muscle atrophy is an inflammation-related complication of type-2 diabetes mellitus (T2DM). Even though regular exercise prevents further deterioration of atrophic status, there is no effective mediator available for treatment and the underlying cellular mechanisms are less explored. In this study, we investigated the therapeutic potential of MCC950, a specific, small-molecule inhibitor of

Importance: Women with adverse pregnancy outcomes, such as preterm delivery or preeclampsia, have higher future risks of cardiometabolic disorders; however, little is known about their long-term mortality risks. A better understanding of such risks is needed to facilitate early identification of high-risk women and preventive actions. Objective: To determine long-term mortality risks associated wi

AbstractSevere perineal trauma (SPT) is a serious complication following vaginal birth. To reduce its incidence rate, various preventive strategies have been implemented in Swedish obstetric units. Collegial midwifery assistance (CMA), involving an additional midwife being present during the active second stage of labour, is a clinical practice that was evaluated in the Oneplus trial, which proved

1 Postadress: Humanekologiska avdelningen, Sölvegatan 12, 223 62 Lund Besöksadress och undervisning: Geocentrum I, Sölvegatan 10, Lund HEKA12:1 Naturuppfattningar i tid och rum, 7,5 högskolepoäng Kursinformation – vårterminen 2020 Version 2019–11–22 2 Kurslitteratur OBS! För instruktioner rörande användning av e-böcker, se ”Elektronisk litteratur” nedan! Böcker (bokhandel/bi

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/heka12_1_schema_vt_2020.pdf - 2025-11-02

SingleRespondentReport_Main Strategic Research Environment (SFO) questionnaire 2010Vinnova As a comprehensive university encompassing natural science, medicine, engineering, humanities, social sciences, a business school, law and a faculty of performing arts, Lund University has a large research potential with both breadth and depth. The breadth is decisive for taking on grand challenges where con

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/verksamhetsuppfoljning_2010_0.pdf - 2025-11-02

https://www.sasnet.lu.se/sites/sasnet.lu.se/files/lu_strategy_report_2011.pdf - 2025-11-02