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Abstract Objective: To evaluate the long-term outcome of men with an initial prostate-specific antigen (PSA) level below 3 ng/mL and whether the free-to-total (F/T PSA) ratio is a useful prognostic marker in this range. Materials and methods: This study is based on 5,174 men aged 50–66 years, who in 1995–1996 participated in the first round of the Göteborg randomized screening trial (initial T-PSA

To assess etiological and clinical consequences of second primary cancers (SPCs) in prostate cancer (PC) patients, we followed newly diagnosed patients to identify men who were diagnosed with a SPC and recorded their causes of death. We used the Swedish Family-Cancer Database to assess relative risks (RRs) and causes of death in SPCs until the year 2015 in patients with a PC diagnosis between 2001

Habitat loss and fragmentation threaten the long-term viability of innumerablespecies of plants and animals. At the same time, habitat fragmentation mayimpose strong natural selection and lead to evolution of life histories with possibleconsequences for demographic dynamics. The Baltic populations of the Glanvillefritillary butterfly (Melitaea cinxia) inhabit regions with highly fragmented habitat

Background: Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection. HLA ligands are recognized by killer immunoglobulin-like receptors (KIRs) expressed on a range of immune cell subsets, governing their proinflammatory activity. We hypothesized that the inherit

Objective: To characterize sociodemographic differences in semen parameters among US men undergoing a semen analysis. Materials and Methods: Men who provided a semen sample were identified from insurance claims between 2007 and 2016. Differences in semen parameters were characterized according to age, race, education, and region. Mean semen parameters and proportions of men with suboptimal paramet

The aim was to evaluate an early prototype of a personalised home lighting system comprising body-worn loggers, a mobile phone, and LED-based lighting with variable intensity and colour temperature. A convenience sample (N = 28, 50% female) wore the devices for 24 hours in the field and were given a demonstration of the lighting system components in a full-scale model of a studio apartment. Partic

Background: Early diagnosis of mild lymphedema and treatment are important to prevent its progress. The tissue dielectric constant (TDC), measuring local tissue water in the skin and upper subcutis, has neither been related to the water displacement method (WDM) nor been used to diagnose mild arm lymphedema in patients at risk. Our aims were to evaluate TDC and WDM in combination with palpation, e

Background:The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.Methods:Over half a million participants

Nitrogenase is the only enzyme that can cleave the strong triple bond inN2. The active site contains a complicated MoFe7S9C cluster. It is believed that itneeds to accept four protons and electrons, forming the E4 state, before it can bind N2.However, there is no consensus on the atomic structure of the E4 state. Experimentalstudies indicate that it should contain two hydride ions bridging two pai

Background Post-operative cognitive dysfunction (POCD) after non-cardiac surgery is a well known problem in some categories of patients. This study aims to evaluate the influence of auditory evoked potential (AEP)-guided anaesthesia on the requirement for anaesthetic drugs and their influence on POCD. Methods Four hundred and fifty patients aged between 18 and 92 years scheduled for ophthalmic sur

The aim of my presentation is to examine the concept of gardening as a cultural construct, and how this concept is created and transformed in picture books from 1968 (the canonical year of student revolt). We often think of the 1970s as the decade when Nordic children’s literature became political. But such a judgment may bepremature. An analysismight show that this claim only offersa schematic imThe aim of my presentation is to examine the concept of gardening as a cultural construct, and how this concept is created and transformed in picture books from 1968 (the canonical year of student revolt). We often think of the 1970s as the decade when Nordic children’s literature became political. But such a judgment may be premature. An analysis might show that this claim only offers a schematic

Objectives: The adaptive humoral immune response following clinical infection with extended spectrum beta-lactamase (ESBL)-producing Enterobacterales (EPE) has not been thoroughly investigated. The aim of this study was to investigate the presence of anti-CTX-M-15 and/or anti-CTX-M-27 IgG antibodies in bacteremia patients diagnosed with EPE compared to a control group consisting of patients suffer

Aims: The population of immigrants from the Middle East in Sweden show a higher prevalence of type 2 diabetes (T2D) compared to native Swedes. The exact reason for this is unknown. Here, we have performed metabolite profiling to investigate these differences. Methods: Metabolite profiling was conducted in Iraqi immigrants (n = 93) and native Swedes (n = 77) using two complementary mass spectrometr

Background Endoscopic papillectomy is a standard treatment for ampullary lesions, which are typically small and confined to the papillary mound. Laterally spreading lesions (LSLs) of the papilla of Vater are a rare ampullary lesion subtype involving extensive duodenal mucosa. Data on endoscopic papillectomy outcomes for LSLs are limited. This study compared endoscopic papillectomy for ampullary LS

Hard turning offers a cost-effective alternative to traditional grinding, yet the tool wear progression limits the broader industrial adoption. During hard turning, the surface microstructure of AISI 52100 steel transforms into a nanocrystalline structure known as white layer, accompanied by significant surface residual stresses. With optimal cutting conditions, surfaces develop nanocrystalline mi

Background: The aim was to evaluate whether an artificial intelligence (AI)-based tool for the automated quantification of the total metabolic tumour volume (tMTV) in patients with Hodgkin lymphoma (HL) could support nuclear medicine specialists in lesion segmentation and thereby enhance inter-observer agreement. Methods: Forty-eight consecutive patients who underwent staging with [18F]FDG PET/CT

The company Victoria Milan provides an online dating service aimed at persons who are already within a committed relationship. Their marketing campaign and their slogan make your life more living, have an affair! has led to a record in amount of complaints from the public to the Swedish advertising ombudsman. Our purpose was to explore how the rhetorical construction of infidelity is characterized

Populärvetenskaplig sammanfattning: Utvärdering av borrhålsloggar. Syftet med detta examensarbete var att göra en utvärdering av wireline borrhålsloggar från borrhålet Kyrkheddinge-4, 3 km öster om Staffanstorp i Skåne. Den undersökta delen av borrhålet Kyrkheddinge-4 befinner sig inom den potentiella reservoarsandstenen, Lundasandstenen. Wireline borrhålsloggar är geofysiska verktyg som används This study is an evaluation of formation characteristics, as derived from wire-line well logs, of the Lund Member in the borehole Kyrkheddinge-4, 3 km east of Staffanstorp, Skåne, Sweden, through the comparison to measured core data. The purpose is to assess the feasibility of using some of the porosity and permeability equations and cross-plots derived for the investigated section and applying th