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I skönlitterär prosa förekommer det strängt taget enbart tre olika temporala texttyper: narration (berättande text, relation), citat (alltså dialog) och berättarens nutid (dvs. passager där en berättare talar i egen sak), och det finns bara två finita tempus att välja emellan: presens och preteritum. Det kan tyckas som om de skönlitterära författarna har ett snävt spelrum att operera inom. Men det

Governments increasingly rely on the use of market instruments to tackle climate change and help decarbonize a deeply fossil fuel-dependent economy. This dissertation examines this trend as one instance of the ‘commodification of carbon’, or the process through which emission reductions are made into commodities and then traded on the market. It engages the commodification framework and related th

Background: Whether and how n-3 and n-6 polyunsaturated fatty acids (PUFAs) are related to type 2 diabetes (T2D) is debated. Objectively measured plasma PUFAs can help to clarify these associations. Methods and Findings: Plasma phospholipid PUFAs were measured by gas chromatography among 12,132 incident T2D cases and 15,919 subcohort participants in the European Prospective Investigation into Canc

IMPORTANCE Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering drugs. Alleles near HMGCR are associated with a higher risk of type 2 diabetes, similar to the increased incidence of new-onset diabetes associated w

Human bone marrow contains a population of non-hematopoietic stromal stem/progenitor cells (BMSCs), which play a central role for bone marrow stroma and the hematopoietic microenvironment. However, the precise characteristics and potential stem cell properties of defined BMSC populations have not yet been thoroughly investigated. Using standard adherent colony-forming unit fibroblast (CFU-F) assay

While there is general agreement on the necessity tomeasure glomerular filtration rate (GFR) inmany clinical situations, there is less agreement on the bestmethod to achieve this purpose. As the gold standardmethod for GFR determination, urinary (or renal) clearance of inulin, fades into the background due to inconvenience and high cost, a diversity of filtrationmarkers and protocols compete to re

A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the onl

Background: Cognitive functioning may have implications for engagement in daily occupations among people with schizophrenia.Objectives: This cross-sectional study explores relationships between time use assessed occupational engagement and cognitive functioning among persons with schizophrenia.Methods: Thirty-nine participants from four mental health care services in Sweden participated. The Profi

Den kände astronomen Tycho Brahe initierade meteorologiska observationer på ön Ven som noterades i endagbok, nästan oavbrutet från oktober 1582 till april 1597. Fastän observationerna huvudsakligen är kvalitativapå grund av dåtida brist på instrument och metoder kan en stor mängd användbar information erhållas fråndagboken beträffande molntäcke, nederbörd, vindhastighet och riktning, temperaturför

Ystads kommun arbetar med en fördjupning av översiktsplanen för staden Ystad med omnejd. Ystads havsnära läge gör att klimatförändringen kommer att innebära stora utmaningar. Stigande havsnivåer väntas leda till ökade erosions- och översvämningsrisker i kustnära områden. Samtidigt är efterfrågan på havsnära boende stor och kommunen planerar att bygga ut staden mot havet. Författarna har utrett kli

Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic therapies by predicting cardiovascular and other health endpoints. We therefore investigated the association of variants in six genes that encode drug targets for obesity or

Background/Objectives:The incidence of microscopic colitis (MC) has increased over the previous decades. In addition to smoking and drugs, currently unidentified environmental factors may have a role. The aim of this study was to determine whether specific dietary or other lifestyle factors were associated with the development of MC.Subject/Methods:The population-based cohort Malmö Diet and Cancer

Introduction: Increased exhaled nitric oxide (NO) levels in asthma are suggested to be through inducible NO synthase (iNOS). The aim of this study was to investigate the expression of iNOS in bronchoalveolar lavage (BAL) cells and tissue from central and peripheral airways and compare it with the exhaled bronchial and alveolar NO levels in patients with asthma vs a control group. Methods: Thirty-t

In the 2011 census of India, more than 2500 settlements have been newly inducted into the category of ‘census towns’ – the lowest size-class of urban settlements in India. This is a staggering figure in light of the observation that a comparable number constituted the total number of all urban settlements recorded since 1900. Furthermore, it has been revealed through aerial images, that a vast maj

The implementation of market solutions has been widely attempted in many different parts of the public sector. This chapter concerns a groundbreaking social reform, which introduced personal assistants for ‘functionally impaired’ people. It was a far-reaching and liberating reform aimed at making disabled people part of society. It replaced collective institutional care with individual choice, in

Homeostasis of short-lived blood cells is dependent on rapid proliferation of immature precursors. Using a conditional histone 2B-mCherry-labeling mouse model, we characterize hematopoietic stem cell (HSC) and progenitor proliferation dynamics in steady state and following several types of induced stress. HSC proliferation following HSC transplantation into lethally irradiated mice is fundamentall