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BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in
Background: Dietary advice remains the cornerstone of prevention and management of type 2 diabetes (T2D). However, understanding the efficacy of dietary interventions is confounded by the challenges inherent in assessing free living diet. Here we profiled dietary metabolites to investigate glycaemic deterioration and cardiometabolic risk in people at risk of or living with T2D. Methods: We analyse
Cities are seen as one of the leading forces in making our societies sustainable and resource efficient. The latest trends of sharing homes, cars, bikes, tools and other goods are fast entering our urban lives. The sharing economy is a consumption-production mode in a city, in which value is generated through transactions between peers or organisations that offer access to their idling or underuti
Forest ecosystems, covering over a third of land on the Earth, play a significant role in the global hydrological cycle, and influence soil erosion and climate change. However, the distribution, movements, quality of water, and hydrological processes in forested ecosystems are not well understood yet. This thesis aims to improve our understanding of the interaction between forest ecosystems and waForest ecosystems, covering over a third of land on the Earth, play a significant role in the global hydrological cycle, and influence soil erosion and climate change. However, the distribution, movements, quality of water, and hydrological processes in forested ecosystems are not well understood yet. This thesis aims to improve our understanding of the interaction between forest ecosystems and wa
Intracerebral haemorrhage and small vessel ischaemic stroke (SVS) are the most acute manifestations of cerebral small vessel disease, with no established preventive approaches beyond hypertension management. Combined genome-wide association study (GWAS) of these two correlated diseases may improve statistical power to detect novel genetic factors for cerebral small vessel disease, elucidating unde
Glioblastoma presents a formidable clinical challenge because of its complex microenvironment. Here, we characterized tumor-associated foam cells (TAFs), a type of lipid droplet-loaded macrophage, in human glioblastoma. Through extensive analyses of patient tumors, together with in vitro and in vivo investigations, we found that TAFs exhibit distinct protumorigenic characteristics related to hypox
Objectives To examine whether multimorbidity aggregates in families in Sweden.Design National explorative family study.Setting Swedish Multigeneration Register linked to the National Patient Register, 1997-2015. Multimorbidity was assessed with a modified counting method of 45 chronic non-communicable diseases according to ICD-10 (international classification of diseases, 10th revision) diagnoses.
A recently proposed overhaul of Swedish criminal law is characte rized by calls for punitive reforms. The government cites changes in the perception of the severity of different crimes, the appropriate general level of repression, the balance between the interests of the penal system, and the function of punishment, as reasons for a more repressive criminal law. Yet the general level of repression
Background: Various factors modulate circulating testosterone in men, affecting interpretation of testosterone measurements. Purpose: To clarify factors associated with variations in sex hormone concentrations. Data Sources: Systematic literature searches (to July 2019). Study Selection: Prospective cohort studies of community-dwelling men with total testosterone measured using mass spectrometry.
Vad gör LU för flyktingar? Terror ökar pressen på IS-forskare Bioplast väntar på dyrare olja Skarvlöst LUNDS UNIVERSITETS MAGASIN | NR 9 | 2015 3D-PRINTNING UTAN GRÄNSER 2 LUM NR 9 | 2015 LUM NR 9 | 2015 3 ”Kasianes hälsar sin syster Tikos hjärtligt. Framför allt önskar vi att du är vid god hälsa. Vi är friska och vår boskap med oss”. Så lyder ett antikt sms. UB-personal är på öppet hus i 3D-print
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-9-2015.pdf - 2026-07-01
29.p65 1Women’s Migration in Contemporary Russian Literature Women’s Migration in Contemporary Russian Literature Karin Sarsenov karin.sarsenov@slav.lu.se 2 CFE Working paper series no. 29 CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY: Box 52 Phone: +46 (0)46-222 88 99 SE-221 00 LUND Fax: +46 (0)46-222 40 06 Sweden Email: cfe@cfe.lu.se CFE Working paper series is published by Centre for European
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp29.pdf - 2026-07-01
2019-08-30 Scientific report Information about the grant Registration number: 2016-07090 Grant recipient: Iwarsson, Susanne Administrating organisation: Lunds univers i tet Project site: Hälsovetenskaper 314500 Project title (english): UserAge: Understanding User Participation in Research on Ageing and Health Grant period: 2017-01-01 - 2019-12-31 Total granted amount: 9,000,000 Grant expiry date:
https://www.case.lu.se/sites/case.lu.se/files/2016-07090_programbidrag_lagesrapport_userage_20190830_x.pdf - 2026-07-01
Importance Active perinatal care increases survival of extremely preterm infants; however, improved survival might be associated with increased disability among survivors. Objective To determine neurodevelopmental outcome in extremely preterm children at 2.5 years (corrected age). Design, Setting, and Participants Population-based prospective cohort of consecutive extremely preterm infants born be
Popular Abstract in Swedish Till processindustrin räknar man bland annat fabriker som tillverkar papper, plast och livsmedel. I en enda fabrik kan det finnas tusentals PID-regulatorer som har till uppgift att styra storheter som tryck, flöden och temperaturer till önskade värden. PID-regulatorns roll i processindustrin har därför jämförts med den arbetsmyran har i myrstacken. Huruvida en enskild mA large process industry can have somewhere between five hundred and five thousand control loops, and PID controllers are used in 90–97% of the cases. It is well-known that only 20–30% of the controllers in the process industry are tuned satisfactorily, but with the methods available today it is considered too time-consuming to optimize each single controller. This thesis presents tools for analys
Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet
More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. Transposable elements comprise about 50% of the genome and co-exist as symbio
Popular Abstract in Swedish Syfte Syftet med denna avhandling var att undersöka om barn födda i Sverige till invandrare (icke-Svenskar) hade en ökad risk för typ 1 diabetes (T1D) och om immunogenetiska markörer för T1D (HLA och icke-HLA genetiska faktorer samt ö-cellsantikroppar) skiljde sig från svenska T1D barn (Svenskar). Målsättningen var också att analysera ärftliga förutsättningar (T1D och TThis thesis examined whether the offspring of immigrants (non-Swedes) to Sweden are at increased risk of Type 1 Diabetes (T1D) when they are born or live in Sweden. It also evaluated if their T1D and T2D-related genes differed from Swedish patients and whether this genetic heritage determined the types and existence of islet autoantibodies at time of diagnosis and affected the classification of di
