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Late mortality and morbidity among long-term leukemia survivors with Down syndrome : A nationwide population-based cohort study

Background: Late health consequences of treatment for childhood leukemia are well documented. Although individuals with Down syndrome (DS) have a substantially increased risk of leukemia, information on late effects in this group is almost nonexistent. The aim of this study was to evaluate the mortality and morbidity among 5-year leukemia survivors with DS. Procedure: We compared 5-year leukemia s

Phase 3 assessment of the automated bone scan index as a prognostic imaging biomarker of overall survival in men with metastatic castration-resistant prostate cancer a secondary analysis of a randomized clinical trial

IMPORTANCE Prostate cancer commonly metastasizes to bone, and bone metastases are associated with pathologic fractures, pain, and reduced survival. Bone disease is routinely visualized using the technetium Tc 99m(99mTc) bone scan; however, the standard interpretation of bone scan data relies on subjective manual assessment of counting metastatic lesion numbers. There is an unmet need for an object

Introducing micro-finance in Sweden

The case describes the first year of efforts to introduce microfinance as a tool to work with vulnerable groups in Sweden, more particularly ex-convicts, former drug-addicts and long-term unemployed women of immigrant background. The teaching objective is to discuss whether micro-finance can be seen as a tool to catalyze social change in developed welfare states such as Sweden, or if it rather rei

Adaptive and Application-agnostic Caching in Service Meshes for Resilient Cloud Applications

Service meshes factor out code dealing with inter-micro-service communication. The overall resilience of a cloud application is improved if constituent micro-services return stale data, instead of no data at all. This paper proposes and implements application agnostic caching for micro services. While caching is widely employed for serving web service traffic, its usage in inter-micro-service comm

Konkurrens mellan honungsbin och vilda bin : – evidens, kunskapsluckor och möjliga åtgärder

Denna forskningsöversikt är en sammanställning av de europeiska vetenskapligastudier som innehåller empirisk evidens när det gäller om och hur honungsbinpåverkar vilda bin genom att konkurrera om födoresurser. Sammanställningengår igenom i vilken mån honungsbins och vilda bins födoval överlappar.Dessutom redovisas i vilken mån studierna visar att honungsbin har effekt påvilda bins blombesök och reCompetition from honey bees on wild bees – effects, knowledge gaps and possible interventions.In this review, we have compiled the European emp irical evidence available in the scientific literature on the effects of honey bees on wild bees through competition for food resources. We have also inventoried ongoing initiatives in northern Europe concerning competition between honey bees and wild bees

Phase-Noise Compensation for OFDM Systems Exploiting Coherence Bandwidth : Modeling, Algorithms, and Analysis

Phase-noise (PN) estimation and compensation are crucial in millimeter-wave (mmWave) communication systems to achieve high reliability. The PN estimation, however, suffers from high computational complexity due to its fundamental characteristics, such as spectral spreading and fast-varying fluctuations. In this paper, we propose a new framework for low-complexity PN compensation in orthogonal freq

Design of robust 2,2′-bipyridine ligand linkers for the stable immobilization of molecular catalysts on silicon(111) surfaces

The attachment of the 2,2′-bipyridine (bpy) moieties to the surface of planar silicon(111) (photo)electrodes was investigated usingab initiosimulations performed on a new cluster model for methyl-terminated silicon. Density functional theory (B3LYP) with implicit solvation techniques indicated that adventitious chlorine atoms, when present in the organic linker backbone, led to instability at very

Angular-Domain Massive MIMO Detection

In massive multiple-input multiple-output (MIMO) systems, the large size of channel state information (CSI) matrix significantly increases the computational complexity of uplink detection and size of required memory to store the channel data. To address these challenges, we propose to perform detection in the angular domain, where the channel information can be presented in a more condensed way. T

FedApp: a Research Sandbox for Application Orchestration in Federated Clouds using OpenStack

Multi-cluster federation is envisioned to be the next-generation cloud infrastructure, where it will play a vital part in the realization of concepts such as edge and fog computing. Orchestrating applications in federated environments poses new challenges to well-known research problems in various fields, such as load-balancing, auto-scaling, resource allocation and service migration. However, as

Closing the Feedback Loop in DevOps Through Autonomous Monitors in Operations

DevOps represent the tight connection between development and operations. To address challenges that arise on the bor- derline between development and operations, we conducted a study in collaboration with a Swedish company responsible for ticket management and sales in public transportation. The aim of our study was to explore and describe the existing DevOps environment, as well as to identify h

Application of full-reference video quality metrics in IPTV

Executing an accurate full-reference metric such as VQM can take minutes in an average computer for just one user. Therefore, it can be unfeasible to analyze all the videos received by users in an IPTV network for example consisting of 10.000 users using a single computer running the VQM metric. One solution can be to use a lightweight no-reference metrics in addition to the full-reference metric

A low latency and area efficient FFT processor for massive MIMO systems

A low-latency and area-efficient FFT/IFFT scheme is presented. The main idea is to utilize OFDM guard bands to reduce the operation counts and processing time, which results in 42% latency reduction compared to the reported pipelined schemes. To realize this idea, a modified pipelined architecture and an efficient data scheduling scheme are proposed. Furthermore, the proposed architecture is scala

Using a Visual Abstract as a Lens for Communicating and Promoting Design Science Research in Software Engineering

Empirical software engineering research aims to generate prescriptive knowledge that can help software engineers improve their work and overcome their challenges, but deriving these insights from real-world problems can be challenging. In this paper, we promote design science as an effective way to produce and communicate prescriptive knowledge. We propose using a visual abstract template to commu

CA 19-9 and CA 125 as potential predictors of disease recurrence in resectable lung adenocarcinoma

Objectives: Among patients who underwent primary surgery for non-small cell lung cancer (NSCLC), recurrent disease is frequent and cannot be accurately predicted solely from TNM stage and histopathological features. The aim of this study was to examine the association of tumor markers in pre-operative serum with recurrent disease. Material and methods: Blood samples were collected prior to lung ca

A Focus on Critical Thinking or Linguistic Features?

The aim of the study is to research upper secondary teachers’ attitudes towards, and use of, critical perspectives in teaching literature in the subject of English in Sweden. This is done in relation to the inequality issues identified in the Swedish school context, the Swedish National Curriculum for the Upper Secondary School and the syllabi for English, along with a theoretical framework based

Scattering computations using a rotationally symmetric solver implemented in open source finite elements

We summarize the theory and implementation of an open source solver for rotationally symmetric scatterers. The purpose of the code is to compute reference solutions for electrically large radome problems. The rotational symmetry decouples the azimuthal modes, enabling the three-dimensional problem to be broken down into a sequence of decoupled two-dimensional problems which require much less memor