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To study the absorption, metabolism and kinetics, the AKG ( in different concentrations) was administered intravenously, intra-portally, orally and directly into the ileum or duodenum of pigs, chronically fitted with portal and jugular catheters and T-shaped cannula at the duodenum and ileum. Additionally, this study was conducted to determine the influence of low pH, Fe2+ or/ and SO42- on AKG gut

Class I and class II MHC-restricted T cells specific for proteins present in myelin have been shown to be involved in autoimmunity in the central nervous system (CNS). It is not yet known whether CD1d-restricted T cells reactive to myelin-derived lipids are present in the CNS and might be targeted to influence the course of autoimmune demyelination. Using specific glycohpid-CD1d tetramers and clon

Combining nutritional supplements to achieve synergistic benefit is a common practice in the nutraceutical industry. However, establishing. added health benefit from a combination of natural ingredients is often assumed, untested and without regard to the principle of metabolic competition between the active components. Here, we report on the combination of a cat's claw water extract (C-Med-100, c

Cell surface proteins of the human gastric pathogen Helicobacter pylori, reference strain CCUG 17874, were extracted with acid glycine and fractionated by heparin affinity chromatography. The extracts were subsequently analysed using high-resolution two-dimensional gel electrophoresis (2-DE) and immunoblotting. Four proteins of low molecular masses (25-30 kDa) stained by Coomassie R-350, were iden

I present the status of the T(HE)PEG project for creating a common platform for implementing C++ event generators. I also describe briefly the status of the new versions of P-YTHIA, (HERWIG) and A(RIADNE) which are implemented using this framework. (c) 2005 Elsevier B.V. All rights reserved.

Aim: In this study, we employed chimeric human/ mouse Proteinase 3 ( PR3) proteins as tools to induce an autoantibody response to PR3 in rats and mice. Method: Rats and mice were immunised with recombinant human PR3 ( HPR3), recombinant murine PR3 ( mPR3), single chimeric human/ mouse PR3 ( HHm, HmH, mHH, mmH, mHm, Hmm) or pools of chimeric proteins. Antibodies to mPR3 and HPR3 were measured by EL

The effect of harvest time and storage on dietary fibre content and composition was investigated in six cultivars of white cabbage (Brassica oleracea var capitata). Three cultivars were of early maturity type (SW Nordpol, Rolly and Balbro) and three of late maturity type (Predikant, Hanna and Lion). The average total dietary fibre (TDF) content was 241 g kg(-1) dry matter (DM) (CV = 13), of which

Human immunodeficiency virus-2 (HIV-2) is less pathogenic than HIV-1, and the disease progression in HIV-2-infected individuals seems to be similar to that seen in HIV-1-infected long-term nonprogressors. Cell-mediated immune responses and the production of noncytotoxic CD8(+) T-cell antiviral factors (CAF) and beta-chemokines have been correlated to protection against HIV-1 and associated with as

Structure-function studies are frequently practiced on the very diverse group of natural carbohydrate-binding modules in order to understand the target recognition of these proteins. We have taken a step further in the study of carbohydrate-binding modules and created variants with novel binding properties by molecular engineering of one such molecule of known 3D-structure. A combinatorial library

Human immunodeficiency virus (HIV)-2-specific T lymphocyte proliferative responses were determined in cultures of peripheral blood mononuclear cells from HIV-2-exposed uninfected individuals, HIV-2-infected individuals and HIV-negative controls in Guinea-Bissau. Increased HIV-2-specific T lymphocyte proliferative responses were detected in both groups compared to HIV-negative controls (healthy HIV

BACKGROUND. Androgen deprivation is the only effective systemic therapy available for patients with prostatic carcinoma, but is associated with a gradual transition to a hormone-refractory prostate cancer (HRCAP) in which ligand-independent activation of the androgen receptor has been implicated. The beta(2)-adrenergic receptor (beta(2)-AR) is a well-known activator of the androgen receptor. METHO

BACKGROUND: Early age at first full-term pregnancy and increasing parity are associated with a reduced risk of breast cancer. However, whether pregnancy decreases the risk of early-onset hereditary breast cancer is unknown. There is concern that pregnancy may increase breast-cancer risk in carriers of BRCA1 and BRCA2 germline mutations. We aimed to establish whether pregnancy is a risk factor for

An audio-tactile interactive tourist guide is demonstrated, including the possibility to be guided to points of interest. In contrast with the key-hole like experience of on-screen augmented reality, this guide makes use of the non-visual modalities to create a more immersive augmented experience. Sound windows from the past and verbal historical information complement discrete tactile guidance al

This text is an analysis of the reception of Steven Spielberg´s film Schindler´s List in the Czech Republic. Being a Sudeten German, Oskar Schindler, the hero of the film and the rescuer of hundreds of Jews from the Nazi destruction machinery, made Czechs aware not only or primarily of the atrocities of the Holocaust, but of several Czech-German troublespots of the past, including those related to

Popular Abstract in Swedish I denna avhandling har jag fördjupat mig i de ekologiska sambanden mellan några av de mest påtagliga och kända organismerna i sjöar och dammar, nämligen sjöfåglar, undervattensväxter, smådjur (från och med nu kallade evertebrater, vilket betyder ryggradslösa djur), och i viss grad fisk. Bland sjöfåglarna (här avses främst änder, gäss, svanar och sothöns) finns det både The aim of this thesis was to explore some of the important links between waterfowl and the biota in shallow eutrophic lakes in temperate areas. Waterfowl depend on macroinvertebrates as sources of protein and calcium, which are essential for egg production and growth. Macroinvertebrates in turn depend on submerged vegetation for food and shelter. Increased density of vegetation thus leads to incr

Det svenska miljöpolitiska generationsmålet går ut på att ”till nästa generation lämna över ett samhälle där de stora miljöproblemen är lösta, utan att orsaka ökade miljö- och hälsoproblem utanför Sveriges gränser”. Det är ett ambitiöst mål med tanke på de enorma, ännu olösta, miljöproblem som mänskligheten står inför: klimatförändringar, miljögifter, biologisk utarmning. Målet antogs ursprunglig

Case commentary | “Decision on the Apparent Conflict of Interests in relation to the Legal Representative of Victims a/0015/08...a/0035/08, Prosecutor v. Katanga and Ngudjolo Chui, Case No ICC-01/04–01/07, Pre-Trial Chamber I, 16 July 2008”

In these notes we are going to present a technique which is a multi-dimensional analogue of some methods which are nowadays standard inscattering theory on the real line for the Schrödinger operator. These methods are based on the construction of operators intertwining the Schrödinger operator with the free operator, obtained when the potential term is removed. The multi-dimensional technique us