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We report preliminary experimental and computational studies of the temporal evolution of the harmonics, generated in xenon, by 50-ps pulses from a Nd: YLF laser, amplified in Nd: glass amplifiers, and focused to produce intensities in the range 1013--5 {\texttimes} 1013 W cm{\textminus}2. Measurements were made of the temporal profiles of the seventh- and ninth-order harmonics using a specially m
The interaction among various stakeholder organizations in modern crisis response is very similar to negotiation where each organization has its own goal in addition to a common goal. Decision makers in stakeholder organizations most often have to settle for win-win situations to attain higher joint benefit. In such cases willingness to contribute in joint tasks becomes a prerequisite. In our pres
Popular Abstract in Swedish ”Vi kommo överens om att möten innehålla alla livets möjligheter, och att en människa som levat mycket vet mycket om möten om hon alls vet någonting.” Så uttalar den kvinnliga huvudpersonen i Mannen vid min sida (1933) sin övertygelse efter mötet med älskaren. Denna avhandling fokuserar mötet i Elin Wägners trettiotalsromaner. Genom att analysera detta vill avhandlingsfThe aim of this present thesis is to present the Utopian scheme in Elin Wägner’s novels of the nineteen-thirties: Dialogen fortsätter (1932) (“The Dialogue Continues”), Mannen vid min sida (1933) (“The Man by my Side”), Genomskådad (1937) (“Unmasked”) and Hemlighetsfull (1938) (“Mysterious”). With her authorship Wägner was aiming for a new social order, a radical change, polväxling (a shift of pol
A recent upsurge in rights talk has left a mark on many areas of law and social policy. Areas such as freedom of expression and hate speech that have traditionally been debated in terms of rights, as well as family law and the welfare of children, human trafficking and prostitution, national security and anti-terrorism legislation, economic policy and market development, to mention but a few, have
Innovation and industrial dynamics have grown in importance over the last 40-50 years as we have moved towards a more knowledge intensive society. In an effort to understand these developments in society new research fields have emerged such as innovation and entrepreneurship studies. In general, these two research fields are regarded as rather closely interlinked. In this study we elaborate on th
Background. Some autoimmune and chronic inflammatory disorders are associated with increased risks of non-Hodgkin lymphoma (NHL). Because different NHL subtypes develop at different stages of lymphocyte differentiation, associations of autoimmune and inflammatory disorders with specific NHL subtypes could lead to a better understanding of lymphomagenic mechanisms. Methods: In a population-based ca
The view on reactive oxygen species (ROS) in inflammation is currently shifting from being considered damaging toward having a more complex role in regulating inflammatory reactions. We recently demonstrated a role of ROS in regulation of animal models for the autoimmune disease rheumatoid arthritis. Low levels of ROS production, due to a mutation in the Ncf1 gene coding for the Ncf1 (alias p47pho
Human polyclonal and monoclonal antibodies against pathogens and toxins are potentially useful in the treatment of various diseases. A number of human monoclonal antibodies with protective capacity in vitro have been established by conventional hybridoma technology. However, with the development of phage-display technology, the possibility of specifically tailoring antigen-binding properties has i
In arterial vessel wall characterisation the longitudinal movements of vessels have gained little or no attention. It has been presumed that the arterial vessels move very little in the longitudinal direction. With modern high resolution ultrasound it can, however, be seen that arterial vessels move not only in the circumferential, but also in longitudinal direction. This paper describes a non-inv
Type 1 diabetes is a common, multifactorial disease with strong familial clustering (genetic risk ratio [{lambda}S] ~ 15). Approximately 40% of the familial aggregation of type 1 diabetes can be attributed to allelic variation of HLA loci in the major histocompatibility complex on chromosome 6p21 (locus-specific {lambda}S ~ 3). Three other disease susceptibility loci have been clearly demonstrated
The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection and compared with that of controls without antibiotic (Group III). Both regimens significantly reduced the frequency of post-operative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) compared to the controls.
Periodontitis is an inflammatory disease of the supporting structures of the teeth and is caused by, among other agents, Porphyromonas gingivalis. P. gingivalis is very resistant to killing by human complement, which is present in a gingival fluid at 70% of the serum concentration. We found that the incubation of human serum with purified cysteine proteases of P. gingivalis (gingipains) or P. ging
Three properdin deficiency phenotypes have been reported--complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin protein (type III)--all associated with increased susceptibility to meningococcal disease. Expression of properdin by monocytes was examined in type I deficiency and in two unrelated cases with type II deficiency, one from a Swedish and one from a Da
Background. The incidence of non-Hodgkin lymphoma and prevalence of obesity are increasing globally. A suggested positive association between obesity and risk of non-Hodgkin lymphoma has prompted us to investigate the relationship between body mass index (BMI) and risk of malignant lymphoma subtypes in a population-based case-control study. Methods: Telephone interviews were conducted with 3055 ca
An increased understanding of cellular uptake mechanisms of macromolecules remains an important challenge in cell biology with implications for viral infection and macromolecular drug delivery. Here, we report a strategy based on antibody-conjugated magnetic nanoparticles for the isolation of endocytic vesicles induced by heparan sulfate proteoglycans (HSPGs), key cell-surface receptors of macromo
This paper reports on a joint numerical and experimental investigation of the release of potassium from biomass during gasification process. In this work, laser-induced breakdown spectroscopy (LIBS) was adopted to measure quantitatively the concentration of potassium from gasifying biomass. The effect of temperature on the potassium release is investigated in hot gas mixture of CO2, H2O with diffe
Breast cancer type 1 susceptibility protein (BRCA1) has a multitude of functions that contribute to genome integrity and tumor suppression. Its participation in the repair of DNA double-strand breaks (DSBs) during homologous recombination (HR) is well recognized, whereas its involvement in the second major DSB repair pathway, nonhomologous end-joining (NHEJ), remains controversial. Here we have st
