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INTRODUCTION: Poliomyelitis is currently a rare disease in developed countries, where only vaccinal strains seem to be in circulation, which replace wild poliovirus. Nevertheless, it is still a serious disease for children in underdeveloped countries of Asia and Africa.PATIENTS AND METHODS: We analysed nine strains of poliovirus type 2 isolated from the faecal matter of patients with vaccine assoc
Objective- The Wnt/β-catenin pathway orchestrates development of the blood-brain barrier, but the downstream mechanisms involved at different developmental windows and in different central nervous system (CNS) tissues have remained elusive. Approach and Results- Here, we create a new mouse model allowing spatiotemporal investigations of Wnt/β-catenin signaling by induced overexpression of Axin1, a
This paper gives an overview of some feedback & control systems at Synchrotron SOLEIL that are in use or in development today. Beam stability is crucial and adressed in all SOLEIL aspects; Fast Orbit Feedback is a multi-input multi-output control system made to stabilize beam position perturbations in the low- & high frequency band. In addition, active RF cavities are used to maintain stab
Objectives: To determine clinical characteristics and treatment complications of patients with late-stage Parkinsonism living in nursing homes compared with those living at home. Design: Cross-sectional analysis. Setting and Participants: This study is an analysis of 692 patients with late stage Parkinsonism recruited to an in-depth international study, Care of Late-Stage Parkinsonism (CLaSP). Mea
Cost of flight at various speeds is a crucial determinant of flight behaviour in birds. Aerodynamic models, predicting that mechanical power (Pmech) varies with flight speed in a U-shaped manner, have been used together with an energy conversion factor (efficiency) to estimate metabolic power (Pmet). Despite few empirical studies, efficiency has been assumed constant across flight speeds at 23%. I
Streptococcus pyogenes is a major human pathogen that causes a variety of diseases ranging from mild skin and throat infections to fatal septicemia. In severe invasive infections, S. pyogenes encounters and interacts with components of the extracellular matrix (ECM), including small leucine rich-proteoglycans (SLRPs). In this study, we report a novel antimicrobial role played by SLRPs biglycan, de
Introduction: The spatial peaks QRS-T angle accurately distinguishes children with hypertrophic cardiomyopathy from their healthy counterparts. The spatial peaks QRS-T angle is also useful in risk stratification for ventricular arrhythmias. We hypothesised that the spatial peaks QRS-T angle would be useful for the prediction of ventricular arrhythmias in hypertrophic cardiomyopathy patients under
PURPOSE: Hypermobility at the thumb carpometacarpal (CMC) joint has been proposed as an explanation for abnormal loading and subsequent development of osteoarthritis. Radiographic evaluation of this joint is difficult owing to the obliquity of the articulation. We modified a previously described technique to obtain a bilateral stress radiograph of the thumbs to measure CMC joint laxity. The purpos
Computer-based design analysis is nowadays of utmost importance for most engineering design projects. However, this brings some challenges, among them that of the collaboration between engineering designers and design analysts. Since they work with, and are responsible for, different areas, they do not necessarily have full insight into each other’s way of working. The issue of integration between
In searching for novel peptides with affinity for cadmium, the phage display technique was utilized. In the selection procedure, cadmium ions were immobilized on a metal chelating Sepharose gel. The peptides selected from a hexapeptide library showed no homology to naturally occurring metallothioneins. From the phage clones selected in the biopanning process, phages with affinity for Cd-109 in fre
Abstract in Undetermined Samtalsanalytisk studie som ger metodisk kunskap om jourläkares medicinska frågeprocedurer i samtal med diabetiker efter insulinkoma samt hur ambulanssjuksköterskor och jourläkare sambedömer och kommer fram till ett medicinskt beslut i relation till ambulansriktlinjer.
This paper presents theory and algorithms for validation in system identification of state-space models from finite input-output sequences in a subspace model identification framework. Similar to the case of prediction-error identification, it is shown that the resulting model can be decomposed into an input-output model and a stochastic innovations model. Using the Riccati equation, we have desig
The effect of surface strain on the passive film evolution of SAF 2507 super duplex stainless steel exposed to ambient air and 0.1 M NaCl solution with varying anodic polarization at room temperature has been investigated using in-situ grazing incidence X-ray diffraction (GIXRD) in combination with electrochemical measurements. Surface strain affected the crystallinity of the passive film as such
MRI-based biophysical models are typically validated by comparison to ex-vivo histology of fixed tissue. The fixation process itself and the accompanied autolysis processes strongly modify tissue composition, and lead to MR signal changes, making the validation of biophysical models for in vivo MRI particularly challenging. To better understand the temporal evolution of the fixation process within
BACKGROUND AND AIMS: Helicobacter pylori is the major causative agent in peptic ulcer disease and is strongly implicated in the development of gastric cancer. It has also been linked, less strongly, to cardiovascular disease. The mechanisms by which certain Strains of H pylon induce platelet aggregation through interactions with platelet glycoprotein 1b have been previously described. METHODS: In
Emerging lines of evidence indicate that the cutaneous human papillomavirus (HPV) types that belong to the genus Betapapillomavirus (beta HPV) are involved in the development of nonmelanoma skin cancer. Unlike the situation for mucosal HPV types, highly sensitive and reliable methods to identify characterized cutaneous HPV types in a single assay are limited. Here, we describe a novel one-shot met
Popular Abstract in Swedish Inom svensk mjölkproduktion förekommer en hög frekvens av belastningsbesvär. Vid jämförelser mellan manliga och kvinnliga mjölkare har det visat sig vara stora skillnader avseende besvärsförekomst. Kvinnorna har rapporterat högre frekvens av problem i nästan alla kroppsdelar jämfört med männen. Dessutom har andelen hand- och handledsbesvär visat sig vara anmärkningsvärdThe aims of the thesis were to investigate the prevalence of the upper extremity musculoskeletal disorders in female milkers in relation to other occupational groups; to clarify the relationship between disorders and work environment, psychosocial and life style factors; to compare in a prospective study, pain, ache and discomfort reported by a questionnaire with clinical symptoms and sign; to exa
In recent years, street art has become embedded in popular culture and received growing attention from the art market and art institutions. Work by street artists has entered galleries, auction houses and museums, and some artists have been given the opportunity to create large-scale sanctioned public art projects. Simultaneously, widespread photographic documentation of street artworks and the ci
Popular Abstract in Swedish Den här avhandlingen, vars kontext är staden Jönköping – känd som Smålands Jerusalem – och dess omnejd, vill besvara frågan: Hur utformades och användes berättelsen om missionen i Kina för att åstadkomma och upprätthålla missionsvänskapets hängivenhet? Det var vid skiftet mellan 1880- och 1890-talen, under växande arbetslöshet, bostadsnöd och fattigdom, med konfrontatioThis thesis intends to answer the question: How was the narrative of the mission in China formulated and used to engender and sustain the fervour of the friends of the mission in the 1890s? It was at this time, with growing unemployment, lack of housing, and of poverty – a time when new and challenging ideas emerge – that the interest in the missions to China awoke. The context of the missionary n
Kaposi sarcoma-associated herpesvirus (KSHV) is the most important etiopathological factor of Kaposi's sarcoma (KS) and some specific types of malignant lymphomas. One of the viral lytic genes encodes the KSHV complement control protein (KCP), which functionally mimics human complement inhibitors. Although this protein provides an advantage for evading the complement attack, it can serve as target
