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Popular Abstract in Swedish Avhandlingen behandlar det grekiska landskapet Argolis på östra Peloponnesos och vissa aspekter av livet där under drygt 600 år av romersk överhöghet. I området har man från den tiden funnit lämningar av städer, byar, villor och gårdar så väl som speciella anläggningar för framställning av olivolja, vin och keramik, dessutom badanläggningar, akvedukter, stenbrott, hamnaThis study focuses on the region of Argolid in the eastern part of the Greek Peloponnese during the Roman Imperial era, taking up a variety of aspects of life there based mainly on archaeological evidence. The introduction presents the study area and the background to the study. This is followed in the next chapter by a survey of the various kinds of sites of Roman date found in the Argolid. Citie

Infestation of skin by the parasitic itch mite Sarcoptes scabiei afflicts 300 million people worldwide and there is a need for novel and efficient therapies. We have previously identified a multigene family of serine proteases comprising multiple catalytically inactive members (scabies mite-inactivated protease paralogs (SMIPPs)), which are secreted into the gut of S. scabiei. SMIPPs are located i

Human postural dynamics was investigated in twelve normal subjects by means of a force platform recording body sway induced by bipolar transmastoid galvanic stimulation of the vestibular nerve and labyrinth. We modeled the stabilizing forces actuated by the feet as resulting from complex muscular activity subject to feedback of body velocity and position. Time series analysis demonstrated that a t

Staphylococcus aureus enterotoxin H (SEH) belongs to the staphylococcal enterotoxin (SE) family of superantigens (SAgs). SEH has structural similarities to other SE; however, its biological properties are less well characterized. SEH binds with high affinity to human major histocompatibility complex (MHC) class II and exhibits strong mitogenic activity in human T cells, although it was found to be

Human papillomavirus (HPV) DNA testing can be used to identify women at risk of the development of cervical cancer. The cost-effectiveness of HPV screening is dependent on the type-specific HPV prevalence in the general population. The present study describes the prevalence and spectrum of high-risk HPV types found in a large real-life population-based HPV screening trial undertaken entirely withi

Nuclear star clusters (NSCs) are among the densest stellar systems in the Universe and are found at the centres of many spiral and elliptical galaxies, and up to 40 percent of dwarf galaxies. However, their formation mechanisms, and possible links to globular clusters (GCs), remain debated. This paper uses cosmological simulations of dwarf galaxies at a spatial resolution of pc to present a new fo

Background. Achromobacter xylosoxidans and Pseudomonas aeruginosa are two pathogens that cause persistent airway infections in individuals with cystic fibrosis (CF). The persistence of P. aeruginosa is partly due to a high capacity to form biofilms and the ability to exert antagonism against other bacteria. Loss of microbial diversity in conjunction with chronic P. aeruginosa colonizatio

Apolipoprotein E4 (ApoE4), the major genetic risk factor for Alzheimer's disease (AD), is vital for understanding cellular processes involved in AD pathogenesis. Evidence implicates endosomes as a central player in AD, where endosomal enlargement in neurons is among the earliest changes in AD. This enlargement was reported to be enhanced in APOE4 carriers. Cells internalize ApoE into endosomes for

For the first time, reductions in cerebral β-amyloid pathology load and rate of cognitive and functional decline have been achieved in Alzheimer's disease, through pharmacological intervention in randomised controlled trials. However, the results from phase 3 randomised controlled trials of anti-β amyloid monoclonal antibodies are interpreted in different ways, with some experts supporting a clini

This study investigates the use of journey mapping as a tool for visualizing theflow of information in home care. Journey mapping is a design method with the purpose of visualizing the interaction of a user and a product or service. It tries to encompass the whole user experience including actions and touch points between user and product, feelings and other related information. Hence, the visuali

Objectives: To determine the effect of amoxicillin treatment on resistance selection in patients with community-acquired lower respiratory tract infections in a randomized, placebo-controlled trial. Methods: Patients were prescribed amoxicillin 1 g, three times daily (n = 52) or placebo (n = 50) for 7 days. Oropharyngeal swabs obtained before, within 48 h post-treatment and at 28-35 days were asse

Echoing the roaring success of their bulk counterparts, nano-objects built from organolead halide perovskites (OLHP) present bright prospects for surpassing the performances of their conventional organic and inorganic analogues in photodriven technologies. Unraveling the photoinduced charge dynamics is essential for optimizing the optoelectronic functionalities. However, mapping the carrier-lattic

The objective of the study was to investigate the antigen specificity and occurrence of individual autoantibodies in mothers of children diagnosed with atrioventricular (AV) block in a nation-wide setting. Patients with AV block detected before 15 years of age were identified using national quality registries as well as a network of pediatric and adult cardiologists and rheumatologists at the six

Bruton's tyrosine kinase (Btk) is encoded by the gene that when mutated causes the primary immunodeficiency disease X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency (Xid) in mice. Btk is a member of the Tec family of protein tyrosine kinases (PTKs) and plays a vital, but diverse, modulatory role in many cellular processes. Mutations affecting Btk block B-lymphocyte develop

Neisseria meningitidis serogroup B (MnB) is a leading cause of invasive meningococcal disease in adolescents and young adults. A recombinant factor H binding protein (fHBP) vaccine (Trumenba(®); bivalent rLP2086) was recently approved in the United States in individuals aged 10-25 years. Immunogenicity and safety of 2- or 3-dose schedules of bivalent rLP2086 were assessed in adolescents.

Innate immunity is essential for the anti-microbial defense, but excessive immune activation may cause severe disease. In this study, immunotherapy was shown to prevent excessive innate immune activation and restore the anti-bacterial defense. E. coli-infected Asc−/− mice develop severe acute cystitis, defined by IL-1 hyper-activation, high bacterial counts, and extensive tissue pathology. Here, t

Based on observations obtained with the Nordic Optical Telescope (NOT) we investigate the spectral variability of the Herbig Ae star RR Tau. This star belongs to the UX Ori family, characterized by very deep fadings caused by the screening of the star with opaque fragments (clouds) of the protoplanetary discs. At the moments of such minima one observes strong spectral variability due to the fact t

Popular Abstract in Swedish Hur ser det ut inuti protonen? Vi vet att protonen består av mindre partiklar. Den utgörs egentligen av tre st. kvarkar, men där finns också en mängd gluoner och virtuella kvarkar och antikvarkar. Gluonerna är de partiklar som håller ihop de tre kvarkarna (valenskvarkarna) i ett så hårt grepp att protonen blir väldigt liten (ca. 100000 ggr mindre än en atom). Det är deIn this thesis, we give a description of the detailed structure of the proton and a description of the final-state properties in electron-proton scattering. Qualitative results, in a purely gluonic scenario with the leading log approximation, and quantitative results, where quarks are included and some sub-leading corrections have been made, are presented. The quantitative results are in fair agre

The objective of this paper is to demonstrate the legal implications for asylum-seekers flowing from their resort to falsified documents as a method of gaining access to the territory of asylum countries. Article 31(1) of the Refugee Convention is supposed to act as a shield against punishment for illegal entry. However, the paper identifies four issues relating to the application of Article 31 wh