Filetype
Chondroitin sulfate (CS) and dermatan sulfate (DS) are expressed in significant amounts in the brain and play important roles in the development of the central nervous system in mammals. CS and DS structures are often found in a single CS/DS hybrid chain. The L-iduronic acid (IdoA)-containing domain, which defines a DS-type domain, appears key to the biological functions of the CS/DS hybrid chain.
Assembly of the functional complexes of the mitochondrial respiratory chain requires sophisticated and efficient regulatory mechanisms. In plants, the subunit composition and assembly factors involved in the biogenesis of cytochrome c oxidase (complex IV) are substantially less defined than in mammals and yeast. In this study, we cloned maize (Zea mays) Small kernel 11 (Smk11) via map-based clonin
Background: The importance of alerting health care systems of patients carrying multidrug-resistant bacteria (MRB) is highlighted in numerous guidelines. In the absence of electronic alert systems, notification cards are often recommended, but have rarely been evaluated. We evaluated patient experiences of receiving and using a methicillin-resistant Staphylococcus aureus (MRSA) notification card.
Recent data shows that fibroblast growth factor 14 (FGF14) binds to and controls the function of the voltage-gated sodium (Nav) channel with phenotypic outcomes on neuronal excitability. Mutations in the FGF14 gene in humans have been associated with brain disorders that are partially recapitulated in Fgf14(-/-) mice. Thus, signaling pathways that modulate the FGF14:Nav channel interaction may be
Smooth muscle cell (SMC) proliferation is a key process in stabilization of atherosclerotic plaques, and during restenosis after interventions. A clearer understanding of SMC growth regulation is therefore needed to design specific anti-proliferative therapies. Retinoic acid has been shown to inhibit proliferation of SMCs both in vitro and in vivo and to affect the expression of extracellular matr
Protein kinase B is known to mediate a number of biological responses to insulin and growth factors, its role in glucose uptake being one of the most extensively studied. In this paper, we have employed a recently described allosteric inhibitor of PKB, Akti, to clarify the role of PKB in lipid metabolism in adipocytes - a subject that has received less attention. Pretreatment of primary rat and 3T
To analyze the role of the classical and alternative pathways of complement activation in the effector phase of arthritis, we have induced arthritis in C3- and factor B (FB)-deficient (C3(-/-) and FB-/-) DBA/1J mice using well-defined monoclonal IgG2b and IgG2a antibodies to type II collagen. In control DBA/1J mice, severe swelling of the joints, destruction of cartilage and erosion of bone develo
Avdelningen för kursadministration ansvarar för fakultetens samtliga utbildningsprogram på grund- och avancerad nivå, utom läkarprogrammet. Avdelningen hanterar även kursadministration för fristående kurser och forskarskolan.This division provides course administration for all the faculty’s educational programmes at Bachelor and Master level (except the Medical Programme), as well as freestanding courses and the Research School.
High-resolution video generates substantial volumes of data that exceed typical network transmission capabilities, forcing a trade-off between video quality and bandwidth constraints. This thesis explores region-based compression techniques for sports video that intelligently allocate bits based on visual importance, preserving quality where it matters most while reducing bandwidth in less critica
The glycosaminoglycan hyaluronic acid (HA) is an important component of the extracellular matrix (ECM) in the brain. CD44 is a cell adhesion molecule that binds to HA in the ECM and is present on astrocytes, microglia and certain neurons. Cell adhesion molecules have been reported to be involved in anxiety and mood disorders. CD44 levels are decreased in the cerebrospinal fluid (CSF) of depressed
Bokhistorisk forskning kretsar kring boken och andra dokumenttyper som fysiska föremål och kring samspelet mellan individen, samhället och den grafiska kommunikationen i såväl äldre som modern tid. Tryckkulturens materiella och sociala historia, de grafiska teknikernas funktion och betydelse i empiriskt och historiskt såväl som teoretiskt hänseende samt bokens, bildens och typografins funktioner oBook history research encompasses the book and other document types as physical objects as well as the interaction between the individual, society and graphical communication through out history. The material and social history of print culture, and the function and significance of graphical techniques in empirical and historical as well as theoretical terms constitute key areas of the division’s
Forskningen på avdelningen är mångsidig och länkas samman genom seminariet i medierad kultur och information. Forskningen genomsyras av en kritisk analys av digitaliseringen av kultur och samhälle som inkluderar forskningsteman såsom kulturarvsinstitutioner, informationens infrastruktur, kulturpolitik, förlag, bokmarknad, konsumtion och digitalt vardagsliv, läsning, lyssning och förändrade litteraThe research conducted at the division is multifaceted and include several disciplines, all of which get regularly presented at our joint seminar “Mediated Culture and Information. A critical analytical perspective on the digitalization of culture and society permeates our research, which focuses on themes such as cultural heritage institutions, infrastructures of information, cultural policy and
