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It is obviously expected that sustainable development is the primary target to raise prosperity and life standards of nations. It is necessary to ensure social, political, and economic stability. But what about the stimulus factors that motivate sustainable development? Can income inequality be one of them? Some literature has examined the role of income distribution on economic growth, but to te
Perlecan is a heparansulfate proteoglycan found in basement membranes, cartilage, and several mesenchymal tissues that form during development, tumour growth, and tissue repair. Loss-of-function mutations in the perlecan gene in mice are associated with embryonic lethality caused primarily by cardiac abnormalities probably due to hemopericards. The aim of the present study was to investigate the m
Neurocan is a component of the extracellular matrix in brain. Due to its inhibition of neuronal adhesion and outgrowth in vitro and its expression pattern in vivo it was suggested to play an important role in axon guidance and neurite growth. To study the role of neurocan in brain development we generated neurocan-deficient mice by targeted disruption of the neurocan gene. These mice are viable an
The meiotic functions of Emi2, an inhibitor of the APC/C complex, have been best characterized in oocytes where it mediates metaphase II arrest as a component of the cytostatic factor. We generated knockout mice to determine the in vivo functions of Emi2—in particular, its functions in the testis, where Emi2 is expressed at high levels. Male and female Emi2 knockout mice are viable but sterile, in
Understreckare om den yazidiska tragedin
Background: Global health and sustainable development have increasingly been recognised as important parts of medical education, yet education on these issues remains fragmented and scarce. In 2020, a bill to reform the national medical curricula across all Swedish medical schools was introduced, including a greater emphasis on global health and sustainable development. This study aimed to explore
Genetiskt modifierade T celler, kända som CAR-T celler, fungerar som cancerriktade missiler, utformade för att specifikt lokalisera och eliminera tumörceller. Nuvarande versioner har visat enastående framgång i vissa blodcancerformer, men tyvärr är de ineffektiva i andra cancertyper, såsom solida tumörer och andra blodcancerformer. Denna begränsning härstammar främst från bristen på verkligt canceGenetically modified T cells, known as CAR T cells, function like cancer-targeting missiles, designed to specifically locate and eliminate tumor cells, providing promising prospects for more effective cancer therapies. While current iterations have demonstrated unprecedented success in certain blood cancers, they have proven ineffective in other cancer types, such as solid tumors and various blood
The aim of this thesis is to explore what impacts the IDF’s Military Orders regarding water have on Palestinians in the West Bank, taking international humanitarian law (IHL) and International Convention on Civil and Political Rights (ICCPR) into consideration. Thus, to discover whether or not Israel’s actions are compatible with IHL and treats everyone equal before the law, as stated in ICCPR Art
Water is a necessity for human survival, and a lack of sufficient clean water can have severe negative impacts on human health, economic activity, food security and societal relations. Increasing demand on water resources around the globe often leads to conflicts between different water users who compete for available supplies. The Murray Darling Basin (MDB) in Australia is an area that faces many
Medicinen är ett kunskapsfält med humanistisk förankring. Vid Enheten för medicinens historia är målet att nå ökad förståelse för hur den medicinska vetenskapen tagit form över tid och fördjupad insikt kring det sociala sammanhang medicinen verkar i. Genom sin tillhörighet i ämnesområdet Medicinsk humaniora gränsar verksamheten till flera andra akademiska discipliner, såsom idé- och lärdomshistori
