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The relationship between the receptors for the Epstein-Barr virus (EBV) and the C3d fragment of complement was investigated at the molecular level. In the presence of cell-bound C3, virus binding was enhanced in EBV genome-carrying lines. An identical effect could be elicited by C3d at one-quarter the weight amount; C3b and methylamine-treated C3 had no effect on virus binding. The minimum concent

Levodopa-induced dyskinesia (LID) is a debilitating complication of symptomatic therapy in Parkinson's disease. Although there is compelling evidence that striatal pathophysiology is a major driver of LID, the specific circuit mechanisms governing its expression remain obscure. To address this gap, molecular, cellular, and behavioral strategies were used to interrogate circuits in a mouse model of

Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. The known biologic functions reside in the C-terminus, which must be cleaved from the holoprotein to become active. Bovine and porcine cathelicidins are cleaved by elastase from the azurophil granules to yield the active antimicrobial peptides. The aim of this study was to identify the ph

A correlation between the exocrine pancreatic function and growth has been previously demonstrated in growing pigs but the data are inconsistent. This was investigated by studying the growth performance of pigs with exocrine pancreatic insufficiency (EPI) at different ages and maintained under similar conditions. Twelve 7 week old (10.5 +/- 1.3 kg) weaners, and twelve 16 week old (43 +/- 5 kg) gro

H-kininogen (high-molecular-mass kininogen, HK) is the precursor of the vasoactive peptide hormone bradykinin (BK). Previous work has demonstrated that HK binds to Streptococcus pyogenes through M-proteins, fibrous surface proteins and important virulence factors of these bacteria. Here we find that M-protein-expressing bacteria absorb HK from human plasma. The HK bound to the bacteria was found t

Ribosomes are the protein synthesizing factories of the cell, polymerizing polypeptide chains from their constituent amino acids. However, distinct combinations of amino acids, such as polyproline stretches, cannot be efficiently polymerized by ribosomes, leading to translational stalling. The stalled ribosomes are rescued by the translational elongation factor P (EF-P), which by stimulating pepti

Background: Previous clinical studies have suggested that apolipoprotein M (apoM) is involved in glucose metabolism and plays a causative role in insulin sensitivity. Objective: The potential mechanism of apoM on modulating glucose homeostasis is explored and differentially expressed genes are analyzed by employing ApoM deficient (ApoM-/-) and wild type (WT) mice. Methods: The metabolism of glucos

This study examines how the sharing economy is utilized in an emerging area to promote social sustainability. Sege Park in Malmö provide this study's research area. This community served as a testbed for a Sharing Cities Sweden initiative, with support from Malmö municipality, to create a collaborative neighbourhood. The research contains a document analysis of official planning documents by M

In mudflats, interactions and transfers of nutrients and secondary metabolites may drive ecosystems and biodiversity. Foraminifera have complex trophic strategies as they often rely on bacteria and eukaryotes or on potential symbionts for carbon and nitrogen resources. The capacity of these protists to use a wide range of adaptive mechanisms requires clarifying the relationships between them and t

In Armenia, women are systematically excluded from political processes and issues related to gender equality and women’s rights are not politically prioritized. In the absence of this prioritization, civil society actors play a vital role in promoting and addressing issues related to women. Inclusion is often promoted as a key element in democratization processes and this study takes a gender pers

Protokoll fört vid årsstämma i LU Holding AB, org.nr 556500-1467, den 24 juni 2024 i Lund Närvarande aktieägare Antal aktier Antal röster Lunds universitet genom Erik Renström 100 __________ 100 __________ Summa 100 100 Dessutom var Kristina Eneroth och Christine Widstrand närvarande. § 1 Ordförande Stämman öppnades av Erik Renström som valdes till ordförande vid stämman. Noterades att ordföranden

https://www.innovation.lu.se/sites/innovation.lu.se/files/2024-08/A%CC%8Arssta%CC%88mmoprotokoll%20LU%20Holding%202024%20signerat.pdf - 2026-07-24

The aim of the study has been to investigate how discriminatory factors interlink and are conceptualized in governmental policies and strategies, within the field of gender equality and anti-racism work in Sweden. The Study used WPR approach developed by Bacchi as the method of policy analysis, a theoretical lens of intersectionality has been used to understand who the documents are representing i

Thymus colonisation and thymocyte positioning are regulated by interactions between CCR7 and CCR9, and their respective ligands, CCL19/CCL21 and CCL25. The ligands of CCR7 and CCR9 also interact with the atypical receptor CCRL1 (also known as ACKR4), which is expressed in the thymus and has recently been reported to play an important role in normal alpha beta T-cell development. Here, we show that