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The purpose of the study was to investigate whether baseline quality of life (QoL) and changes in QoL scores from baseline are prognostic for time to progression (TTP) and/or overall survival (OS) in patients with advanced breast cancer receiving docetaxel (T) or sequential methotrexate and 5-fluorouracil (MF). QoL was assessed at baseline and before each treatment using the European Organization
Prophylaxis is defined as the regular administration of clotting factor concentrates to prevent bleeding. Extensive data from observational studies and a recent randomized controlled trial (have established that early prophylactic treatment prevents bleeds and arthropathy in boys with severe haemophilia. The initiation of prophylaxis in young children remains challenging. To prevent arthropathy, p
Shaken baby syndrome has typically been associated with findings of subdural haematoma, retinal haemorrhages and encephalopathy, which are referred to as the triad. During the last decade, however, the certainty with which the triad can indicate that an infant has been violently shaken has been increasingly questioned. The aim of this study was to determine the diagnostic accuracy of the triad in
Objectives: Ambulance services and stroke alerts reduce the time from stroke onset to acute stroke diagnosis. We describe the use of stroke alerts and ambulance services in different hospitals and patient groups and their relationship with reperfusion therapy. Methods: This nationwide study included 49,907 patients admitted with acute stroke who were registered in The Swedish Stroke Register (Riks
PURPOSE: To assess the significance of a patent inferior mesenteric artery (IMA) and presence of intrasac thrombus on the outcome of endovascular aneurysm repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA). METHODS: Between June 2004 and June 2007, 114 AAA patients (100 men; mean age 75 years, range 56-87) treated electively with a bifurcated stent-graft were assessed with computed tomog
The scope for wastewater treatment plants (WWTPs) widens to consider not only water quality and cost, but also energy efficiency and greenhouse gas (GHG) emissions. The on-going research project, “Development and dynamic analysis of operational strategies for enhanced energy efficiency of wastewater treatment systems” aims to develop a tool for integrated evaluation of energy efficiency and greenh
Abstract The food industry and we consumers face a major challenge, to reduce food waste. We consumers have a food waste of about 95 kilos a year. Of this, approximately 28 percent is considered to be thrown away on incorrect grounds. Bread waste amounts to 80,400 tonnes each year. The loss occurs throughout the value chain. One of the reasons for the high waste of consumers is that the bread
This study aims to explore how professionals working with preventive social work reason regarding the understanding of the term preventive social work. Furthermore, the study looked into how current discourses were presented by the social workers. In addition, we also aimed to explore the potential benefits and challenges associated with preventive social work. This was examined in light of the ne
Det är inget ovanligt med inkomstöverföringar mellan företag i en internationell företagsgrupp, d.v.s. att medel som inte utgör en marknadsmässig ersättning för en motprestation överförs mellan företag i intressegemenskap. Motiven för detta kan vara att minska inkomstskatten i ett högskatteland genom att överföra vinster till ett mer skatteförmånligt land, eller att minska den totala skattebelastnThis thesis aims to analyze the elements of transfer pricing with emphasis on the peculiarities that the nature of intellectual property involve and the difficulties that enterprises may face when implementing transfer pricing. The concept of transfer pricing relates to the system of assessing the price for the transfer of goods, services and intangibles between member entities of a multinational
BACKGROUND: We compared the association of levosimendan or dobutamine with norepinephrine for the maintenance of systemic and hepatosplanchnic perfusion during early endotoxemic shock. METHODS: Twenty anesthetized pigs (26.8 +/- 0.5 kg) were instrumented with flow probes and catheters to monitor systemic and regional perfusion as described in our companion article in this issue of the journal. Two
Self-Organizing Network (SON) functions include self-configuration, dynamic optimization and self-healing of networks. In the era of 5G, mobile operators are increasingly exploring areas of SON through Machine Learning (ML) techniques. It is seen that 5G packet switched networks are often hit with radio link failures, an important Key Performance Indicator (KPI). Reasons for a dropped call ranges
At Tampere in 1999, the principle of mutual recognition was declared the cornerstone of criminal law cooperation within the European Union. The idea was that a Member State shall recognise a judicial decision in criminal matters taken by a judicial authority in another Member State as if the decision had been taken by one of its own judicial authorities. The argument put forward was that mutual reÖmsesidigt erkännande utsågs till hörnstenen i det straffrättsliga samarbetet inom the europeiska unionen i Tammerfors (Tampere) 1999. Tanken är att en medlemsstat ska erkänna ett juridiskt beslut fattat av en behörig instans i en annan medlemsstat som om beslutet var fattat av en av statens egna behöriga instanser. Det huvudsakliga argumentet för ömsesidigt erkännande var att det skulle medföra e
During the last decade, crimes made in the name of honour, have appeared in the Swedish society and have become the focus of debates and research. Honour killing and compulsory marriage are deeds made in the name of honour and are also controlling and limiting the every-day life of youths´. The school, where the youth can meet people of the same age, becomes a very important place for these boys a
Cardiac arrest effectiveness trials have traditionally reported outcomes that focus on survival. A lack of consistency in outcome reporting between trials limits the opportunities to pool results for meta-analysis. The COSCA initiative (Core Outcome Set for Cardiac Arrest), a partnership between patients, their partners, clinicians, research scientists, and the International Liaison Committee on R
Cardiac arrest effectiveness trials have traditionally reported outcomes that focus on survival. A lack of consistency in outcome reporting between trials limits the opportunities to pool results for meta-analysis. The COSCA initiative (Core Outcome Set for Cardiac Arrest), a partnership between patients, their partners, clinicians, research scientists, and the International Liaison Committee on R
BACKGROUND: Opioid-related deaths have increased in Western countries over recent decades. Despite numerous studies investigating opioid-related mortality, only a few have focused on the lives of the deceased individuals prior to their deaths, specifically regarding contact with care-providing authorities such as health, social and correctional services. Furthermore, a change has been noted in the
Purpose: Surgery is recommended for most patients with gastro-entero-pancreatic neuroendocrine neoplasias (GEP-NENs). Rates of complications and perioperative mortality have been reported in few mostly retrospective single-center series, but there has been no detailed analysis on risk factors for perioperative complications and mortality to date. Methods: Data of patients with GEP-NENs operated be
CuInSe2 (CISe) colloidal quantum dots (QDs) display promising applications in photodetection especially within near-infrared (NIR) regions due to their high extinction coefficient and environmental-friendly. However, the high trap density and poor crystal quality introduced by the ternary structure result in low photodetection of CISe QDs devices. Herein, we dope transition metal manganese ions (M
Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. Certain plant varieties have proved to be particularly vital, have a long history as cultivars, and are today understood as heritage plants. Many have spread over centuries and are today regarded as ‘belonging’ and as more or less Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. Certain plant varieties have proved to be particularly vital, have a long history as cultivars, and are today understood as heritage plants. Many have spread over centuries and are today regarded as ‘belonging’ and as more or less
Soils are subject to varying degrees of direct or indirect human disturbance, constituting a major global change driver. Factoring out natural from direct and indirect human influence is not always straightforward, but some human activities have clear impacts. These include land-use change, land management and land degradation (erosion, compaction, sealing and salinization). The intensity of land
