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Popular Abstract in Swedish Hjärt- och kärlsjukdomar är den största enskilda orsaken till en för tidig död i västvärlden. För att öka kunskapen om dessa sjukdomar är det viktigt att finna mätmetoder, gärna icke-invasiva, som kan användas för att studera tidiga yttringar av hjärt- och kärlsjukdomar. Förändringar av de mekaniska egenskaperna i artärerna kan vara en sådan tidig yttring. För att få etCardiovascular diseases constitute the major cause of morbidity and mortality in the Western World. To increase our knowledge of cardiovascular diseases, it is important to find methods, preferably non-invasive ones, to study very early manifestations of vascular disease. Changes in the mechanical properties of the arteries can be an early manifestation of vascular disease. Further, changes in the

Aim. Endovascular repair of complicated type B dissections has evolved as a promising alternative to open repair. Previous studies have indicated that continued false lumen flow is a predictor of continued aortic dilatation and risk of rupture during follow-up. This multicenter study was conducted to analyze the postoperative changes of the false lumen after endografting of complicated type B diss

OBJECTIVES: To investigate the effects on serum lipids, plasma fibrinogen, plasma insulin, plasma C-peptide and blood glucose, of smoking cessation after 4 months. To develop a group-based smoking intervention programme in primary health care. SETTING: Twenty health centres in primary health care in southern Sweden. SUBJECTS: Four hundred habitual smokers (> 10 cigarettes per day-1, > 10 years), r

Popular Abstract in Swedish Denna avhandling består av fyra separata artiklar. Den gemensamma nämnaren för alla artiklarna är att de behandlar pengar och nätverkseffekter. En vara med nätverkseffekter är en vara där nyttan av varan är beroende av hur många andra individer som använder sig av varan. Ett typexempel i litteraturen är faxmaskiner: ju fler som har en fax, desto större nytta har man av This thesis contains four separate papers in the field of monetary economics. The common basis for all the papers is that they deal with money and network effects in one way or another. Although the common basis is the same in all the articles, different approaches are used: theory, econometrics and history of economic thought. This first essay focuses on the network effect in the use of money an

Popular Abstract in Swedish Lödda kompakta plattvärmeväxlare används i stor utsträckning i kyl – och värmepumpanläggningar samt luftkonditioneringsanläggningar. Såväl enfasvärmeutbyte, dvs värmeutbyte mellan två vätskor, som fasomvandling genom kondensation och förångning är viktiga tillämpningsområden. Apparaterna användes inom industri, hushåll, samhälleliga inrättningar mm. Prestandan för olikaThis thesis work presents various performance estimation methods of compact brazed plate heat exchangers (BPHE) operating in single phase, condenser, evaporator, cascaded and transcritical applications. Such methods play a vital role in development of heat exchanger selection software and during geometry parameter estimation in the new product development process. The suitability of employing comm

In order to assess the role of striatal dopamine (DA) afferents in L-DOPA-induced dyskinesia, we have studied a large series of rats sustaining 2, 3, or 4 unilateral injections of 6-hydroxydopamine (6-OHDA) in the lateral striatum. This type of lesion produced a dose-dependent depletion of DA fibers in the caudate-putamen, which was most pronounced in the lateral aspects of this structure. An addi

The purpose of the present study was to investigate the amplifying function of the nucleus accumbens septi region (NAS) in 6-hydroxydopamine (6-OHDA)-induced rotational behaviour by implanting fetal dopamine (DA)-rich mesencephalic cell suspensions unilaterally in the NAS of rats previously subjected to combined mesostriatal (MS) and NAS 6-OHDA lesions. First, all the rats received a unilateral 6-

Purpose: To prospectively compare nephrotoxicity and radiodensity of plasma hyperosmotic gadolinium chelates (attenuation-osmotic ratio of 1: 1) with those of plasma iso-osmotic iodine-based contrast media (attenuation-osmotic ratio of 3: 1 or 6: 1) after renal arteriography in ischemic porcine kidneys. Materials and Methods: The local animal care committee approved this study. The following contr

Ghrelin is produced by A-like cells (ghrelin cells) in the mucosa of the acid-producing part of the stomach. The mobilization of ghrelin is stimulated by nutritional deficiency and suppressed by nutritional abundance. In an attempt to identify neurotransmitters and regulatory peptides that may contribute to the physiological, nutrient-related regulation of ghrelin secretion, we challenged the ghre

Aim Africa is identified by the Inter-governmental Panel on Climate Change (IPCC) as the least studied continent in terms of ecosystem dynamics and climate variability. The aim of this study was (1) to adapt the Lund-Postdam-Jena-GUESS (LPJ-GUESS) ecological modelling framework to Africa by providing new parameter values for tropical plant functional types (PFT), and (2) to assess the sensitivity

Popular Abstract in Swedish Kroppens immunförsvar är vårt skydd mot främmande "inkräktare", såsom virus, bakterier och parasiter. Om dessa mikroorganismer tar sig förbi de fysiska barriärerna, dvs. hud, slemhinnor saliv mm, aktiveras immunsystemet. Immun-försvaret kan delas in i det nedärvda eller naturliga försvaret samt det för-värvade försvaret. Det naturliga försvaret aktiveras först och huvudInterleukin (IL)-1beta is one of the most pleiotropic and potent cytokines, produced predominantly by activated monocytes and macrophages. IL-1 plays an important role in normal immunoregulatory processes but also in pathophysiological inflammatory responses. In the present study, we developed a model for active IL-1beta secretion. A retroviral vector containing a cDNA construct encoding the matur

Popular Abstract in English The aim of this thesis is to search for the origins of groups stars with similar kinematics making use of their chemical information. Based on measured elemental abundances from high-resolution spectra, a modified chemical tagging method is used to identify the potential cluster members in two cases. In first case, we employ this method to search for the lost siblings oMost of field stars originate from dissolved star clusters. If the gas cloud is well mixed the stars in the cluster are expected to be chemically homogenous. Although the original kinematical information of a star may be lost under the Galactic dynamic evolution, the chemical signatures are preserved in the form of elemental abundances in individual low-mass stars. The present-day distribution of

Popular Abstract in Swedish Senare års forskning har klart och entydigt pekat på njurens viktiga roll i utvecklingen av högt blodtryck. Det är mycket sannolikt att det föreligger flera av varandra oberoende mekanismer som förklarar uppkomsten av högt blodtryck, men det är möjligt att flera av dessa, på en organfysiologisk, cellfysiologisk eller genetisk nivå kan ha gemensamma patofysiologiska länkStudies were conducted to investigate the role of macula densa (MD)-derived nitric oxide (NO) in regulation of the glomerular filtration (GFR) through the tubuloglomerular feedback (TGF) mechanism. Immunocytochemical localization of the neuronal isoform of NO synthase (NOS) in the kidney showed that this isoform was exclusively located in MD cells. Whole kidney clearance measurements of GFR and mi

Popular Abstract in Swedish Kroppens immunförsvar är en kraftfull organisation som styrs av ett intrikat samspel mellan olika molekyler. Dess främsta uppgift är att försvara kroppen mot främmande ämnen, såsom virus och bakterier. Detta kräver en snabb reaktion, vilken naturen löst i form av ett kaskadsystem, där ett första fåtal molekyler inom loppet av minuter aktiverat miljontals molekyler och cANCA-associated systemic vasculitis (AASV) is a group of inflammatory disorders, characterized by inflammation and necrosis of blood vessels and frequently granuloma formation. Patients with AASV make autoantibodies, so called ANCA, against proteins present in the granules of neutrophils and monocytes, mainly proteinase 3 (PR3) and myeloperoxidase (MPO). Clinically, disease progression is characte

Popular Abstract in Swedish I Sverige utförs cirka 3500 benamputationer varje år. Över 90% av alla amputationer görs på grund av kärlsjukdomar, där förträngningar i blodkärlen försämrar blodflödet med vävnadsdöd och vanligen kallbrand som följd. Det finns i huvudsak tre faktorer som ökar risken för amputation på grund av kärlsjukdom; ålder *80 år, rökning och diabetes. Om man inte tillhör någon avGeneral characteristics and outcome was evaluated in 177 consecutive patients who underwent a major amputation in a defined population. Smoking and diabetes lowered the mean amputation age. Healing failure at six months was seen in 24% of transtibial and in 11% of transfemoral amputees. Preoperative absence of gangrene and hemoglobin >120 g/L increased the risk of healing failure. Six months after

Popular Abstract in Swedish Målet för ceramologisk forskning är att studera och beskriva keramikhantverkstraditioner : krukmakarna, deras produktion och sociala organisation samt användningen af keramikprodukterna. Kunskapen om keramiken gör det möjligt också att studera de mänskliga handlingarna, som keramiken tog del i. Den föreliggande avhandlingen söker att avtäcka kontakt-mönstre mellan olikaThe objective of ceramology is to describe pottery craft traditions; the potters, their production, social organisation and the use of the products. Through this the human actions surrounding the pottery are studied. The objective of the research presented in this thesis is to study patterns of contacts between different, contemporary sites within a limited area through a ceramological analysis of

To demonstrate the psychological importance of social changes in behavioural practice, three interview studies were carried out in Sweden, each in the decade of 1970, 1980 and 1990. All subjects were university students, as were te subjects in a study performed 1959 which served as an "anchor study". The results were analysed using the following three perspectives:(1)Hegemonic social appeals rega

Popular Abstract in SwedishGester betraktas ofta populärt som det mest typiska sättet för språkinlärare att lösa kommunikativa problem. Trots det har gester sällan studerats inom ramen för teorier som rör bruket eller inlärningen av andraspråk. Den här studien avser att redogöra för hur andraspråksinlärare använder spontana eller koverbala gester som kommunikationsstrategier. Gester klassificeras Gesture is always mentioned in descriptions of compensatory behaviour in second language discourse, yet it has never been adequately integrated into any theory of Communication Strategies (CSs). This study suggests a method for achieving such an integration. By combining a cognitive theory of speech-associated gestures with a process-oriented framework for CSs, gesture and speech can be seen as re

OBJECTIVE: Neutrophil deposition in tissues (leukosequestration) after shock may produce local tissue injury from proteases and high-energy oxygen species released from sequestered neutrophils. The initial step in the binding of neutrophils to capillary endothelium is the interaction of adhesion molecule (selectin) receptors between neutrophils and endothelial cells. We quantified leukosequestrati

As cardiovascular diseases have been the most common cause of mortality in the western world for decades, the demand for appropriate diagnostic methods is obvious. To facilitate the examination non-invasive methods are preferable since they do not require sensors within the circulation system. Ultrasonic Doppler is a frequently used technique in non-invasive hemodynamic studies. To increase the a