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Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q

Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Defining extended half-life rFVIII-A critical review of the evidence

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Eur 21620 sv-en

am509781CEE_SV_BAT E U R 2 16 20 MÄNSKLIGA RESURSER www.europa.eu.int/eracareers/europeancharter Europeiska stadgan för forskare Riktlinjer för rekrytering av forskare am509781CEE_SV_BAT 8/12/05 16:25 Page 1 Interested in European research? RTD info is our quarterly magazine keeping you in touch with main developments (results, programmes, events, etc). It is available in English, French and Germa

https://www.lu.se/sites/www.lu.se/files/eur_21620_sv-en.pdf - 2026-06-03

Field2

How do we describe a location on earth? How do we describe a location on Earth? Geodetic reference system http://www.google.co.uk/imgres?imgurl=http://4.bp.blogspot.com/-v2sej--Hf9Y/TbGzN0FeN7I/AAAAAAAAAQ0/dXTA6XAP7Nk/s1600/earth-3d.gif&imgrefurl=http://ods-destruction-carbon-credits.blogspot.com/2011/04/happy-earth-day-from-remtec.html&usg=__1-2G0CU8X0-43x3j7NY4oN1vYS8=&h=1024&w=1024&sz=266&hl=en

https://www.nateko.lu.se/sites/nateko.lu.se/files/field2.pdf - 2026-06-03

Kursplaner & litteraturlistor för service management

HT 2025 Termin 1SEMA11 Grundkurs i service management (30 hp)KursplanLitteraturlistaExaminatorTermin 3SEMA31 Ledning, styrning och utveckling av tjänsteverksamheter (30 hp)KursplanLitteraturlistaExaminatorTermin 5Valfri termin (30 hp)Institutionens fristående kurser (svenska), med platsgaranti:SEMA56 Hållbar marknadsföring (7,5 hp), läsperiod 1 (1/9 – 30/9-25)KursplanLitteraturlistaExaminatorSEMB5

https://www.ses.lu.se/utbildning/studieinformation/kursplaner-litteraturlistor-och-utbildningsplaner/kursplaner-litteraturlistor-kandidatprogrammet-service-management/kursplaner-litteraturlistor-service-management-7 - 2026-06-01

Mdc 5yr pharmacological agents - drug based

Name 1 MDC 5yr Pharmacological agents - Drug based 2017-04-18 Contents: Intake of prescribed and non-prescribed drugs (with brand, atc code and starting year). The data file contains one drug per line, an individual may have multiple lines. # lines: 39 572 records of 14 496 individuals # variables: 6 Selection: All individuals who had participated in the MDC baseline screening, who were alive and

https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/mdc_5yr_pharmacological_agents_-_drug_based.pdf - 2026-06-03

From Genotypes of Immunoglobulin Constant Heavy G Chains (Fcγ) (GM) Genes (IGHG) to Phenotypes in Childhood Asthma.

Background: IgE-mediated allergy is associated with immunoglobulin heavy constant G chain (Fcγ) (GM) genes (IGHG) on chromosome 14q32.3. Investigation of the alternative GM allotypes of γ3, γ1 and γ2 chains has disclosed new structural and functional IgG subclasses and B-cell variants, with possible effects on childhood asthma. Objective: To investigate different IGHG (GM) gene complexes in a