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Purpose This study explored the role of several psychological factors in professional quality of life in nurses. Specifically, we tried to clarify the relationships between several dimensions of empathy, self-compassion, and psychological inflexibility, and positive (compassion satisfaction) and negative (burnout and compassion fatigue) domains of professional quality of life. Methods Using a cros
27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association between CYP27A1 expression and prognosis in a cohort of 193 premenopausal patients with lymph node-negative primary BC with limited exposure to adjuvant systemic can
The diversity of bacteriophages is likely unparalleled in the biome due to the immense variety of hosts and the multitude of viruses that infect them. Recent efforts have led to description at the genomic level of numerous bacteriophages that infect the Actinobacteria, but relatively little is known about those infecting other prokaryotic phyla, such as the purple non-sulfur photosynthetic α-prote
Objective: The Attempted Suicide Short Intervention Program (ASSIP) was adapted for hospital delivery and to address substance use problems as well as evaluated for feasibility, acceptability, and therapist fidelity in a series of preparatory steps (n = 28) and in a pilot randomized controlled trial, RCT (n = 34). Method: In the RCT, patients with suicide attempts and substance use problem(s) with
Background: glucagon secretion and inhibition should be mainly determined by glucose and insulin levels, but the relative relevance of each factor is not clarified, especially following ingestion of different macronutrients. We aimed to investigate the associations between plasma glucagon, glucose, and insulin after ingestion of single macronutrients or mixed-meal. Methods: thirty-six participants
This article assesses the status of the solid waste management system (SWMS) in Karachi, the largest city of Pakistan, using the material flow analysis approach, a widely applied method in waste management (WM) studies. It involves a systematic assessment of the material flows of solid waste under the current WM system. A material flow diagram is developed to visualize the input and output waste f
Introduction: Many studies have assessed the prevalence of alcohol consumption in Iran. In this study, we investigated the prevalence of alcohol consumption in different groups. Material and Methods: We searched international and databases including PubMed, Web of Science, Scopus and we searched two main Farsi-language index databases including Scientific Information Database (SID) and the Irandoc
COVID-19 is associated with myocardial injury caused by ischemia, inflammation, or myocarditis. Cardiovascular magnetic resonance (CMR) is the noninvasive reference standard for cardiac function, structure, and tissue composition. CMR is a potentially valuable diagnostic tool in patients with COVID-19 presenting with myocardial injury and evidence of cardiac dysfunction. Although COVID-19-related
There is a large body of scientific evidence on the climate crisis and flooding in urban areas. Extreme weather events are producing extensive property damage and loss of life and require new modes of flood governance. However, the climate crisis does not stop at the city limits: peri-urban areas have related but distinct flood challenges due to land use change, regulation, perceptions, and capaci
Chorea-acanthocytosis (ChAc), an autosomal recessive disorder, is associated with cognitive and behavioral abnormalities. Previous studies were focused around exploring the functional annotation of VPS13A gene in ChAc, whereas the genetic labyrinth underlying this disease and plausible drug targets were underexplored. In the present study, we have identified the pivotal genes and molecular pathway
Ferritin, the central iron storage protein, has attracted attention as a biomarker of severe COVID-19. Few studies have investigated regulators of iron metabolism in the context of COVID-19. The aim was to evaluate biomarkers for iron metabolism in the acute phase response to community-acquired pneumonia (CAP) caused by SARS-CoV-2 compared with CAP caused by bacteria or influenza virus in hospital
We present a method for estimating fossil fuel methane emissions using observations of methane and ethane, accounting for uncertainty in their emission ratio. The ethane:methane emission ratio is incorporated as a spatially and temporally variable parameter in a Bayesian model, with its own prior distribution and uncertainty. We find that using an emission ratio distribution mitigates bias from us
BackgroundWe aimed to fill the gaps of knowledge concerning incidence rates and temporal trend, clinical features and risk factors for death for M. morganii bloodstream infections in south Sweden.MethodsThis was an observational, population-based study including all patients with at least one blood culture positive for Morganella morganii between 2013-2023 in Skåne, south Sweden.ResultsA total of
Poor preoperative sleep quality and impaired sleep continuity may heighten acute postoperative pain intensity and increase analgesic consumption, with negative implications for recovery, mental and physical health. The main objective of the current review was to investigate the relationship between preoperative sleep disturbance and acute postoperative pain control. Four electronic databases were
Human calcitonin (hCT) is an endogenous polypeptide commonly employed in treating bone resorption-related illnesses, but its clinical application is limited due to its high aggregation tendency. Metalloporphyrins are effective in suppressing amyloid fibrillation, positioning them as potential drug candidates for amyloidogenic disorders like Alzheimer's and type 2 diabetes. In this work, we investi
The Collisional Orogeny in the Scandinavian Caledonides (COSC) project focuses on processes related to the closure of the Iapetus Ocean, causing the Ordovician–Silurian continent– continent collision between Baltica and Laurentia. The rock succession in the second drill core (COSC-2) from the Jämtland County, central Sweden, provides the base for detailed sedimentological, stratigraphic, geophysic
