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De novo active sites for resurrected Precambrian enzymes

Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes : The Case of Serum Paraoxonase 1

Computational Study of the pK_a Values of Potential Catalytic Residues in the Active Site of Monoamine Oxidase B

Monoamine oxidase (MAO), which exists in two isozymic forms, MAO A and MAO B, is an important flavoenzyme responsible for the metabolism of amine neurotransmitters such as dopamine, serotonin, and norepinephrine. Despite extensive research effort, neither the catalytic nor the inhibition mechanisms of MAO have been completely understood. There has also been dispute with regard to the protonation s

Completion of registration of risk factor variables during telephone vs on-site follow-up after myocardial infarction : a nationwide observational study in 101 199 patients from contemporary clinical practice in Sweden

Buxus sempervirens and Laurus nobilis leaves from an archaeological site at 7300 cal BP (La Draga, Spain) provide a better understanding of past vegetation and human activities

Release of halide ions from the buried active site of the haloalkane dehalogenase LinB revealed by stopped-flow fluorescence analysis and free energy calculations

Diachronic forager mobility : untangling the Stone Age movement patterns at the sites Norje Sunnansund, Skateholm and Västerbjers through strontium isotope ratio analysis by laser ablation

Strontium isotope ratios in human teeth from the three Swedish prehistoric Stone Age hunter-fisher-gathering societies Norje Sunnansund (Maglemose), Skateholm (Ertebølle) and Västerbjers (Pitted Ware Culture) were analysed with laser ablation to produce data on both individual movement patterns and societal mobility trends. The analyses of teeth from both Skateholm and Västerbjers displayed homoge

Site-dependent nuclear dynamics in core-excited butadiene

Prey capture by the non-native carnivorous pitcher plant Sarracenia purpurea across sites in Britain and Ireland

The carnivorous pitcher plant Sarracenia purpurea is native to North America, but has been introduced into Europe, where it is now widespread. Understanding of how this species functions in its non-native range is limited. We measured pitcher morphology and prey capture by S. purpurea in its non-native range in Britain and Ireland. Pitchers were removed from different plants at each of six bogs co

Site-specific N-glycan profiles of α₅β₁ integrin from rat liver

Making and Contesting Far Right Sites of Memory : A Case Study on Romania

The protein S-binding site localized to the central core of C4b-binding protein

The role of blogs and news sites in science communication during the COVID-19 pandemic

Analysis of particle size distribution changes between three measurement sites in Northern Scandinavia

Measured aerosol size distributions from three measurement stations and modeled air mass trajectory data were combined to study aerosol dynamics in the boreal forest zone in Northern Scandinavia. Three approaches were used: investigation of new particle formation events, analysis of air masses arriving from ocean to continent, and study of changes in the aerosol size distributions when air masses

Optimal Landfill Site Selection for Solid Waste of Three Municipalities Based on Boolean and Fuzzy Methods: A Case Study in Kermanshah Province, Iran

The importance of on-site evaluation for placing renewable energy in the landscape : A case study of the Búrfell wind farm (Iceland)

A blood test to monitor bee health across a European network of agricultural sites of different land-use by MALDI BeeTyping mass spectrometry

There are substantial concerns about impaired honey bee health and colony losses due to several poorly understood factors. We used MALDI profiling (MALDI BeeTyping®) analysis to investigate how some environmental and management factors under field conditions across Europe affected the honey bee haemolymph peptidome (all peptides in the circulatory fluid), as a profile of molecular markers represen

Improved prediction of site-rates from structure with averaging across homologs

The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site

A Transparent Modelling Workflow for the Assessment of Surface Water-Groundwater Exchange Flux at a PCE Contaminated Site