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Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis
Ligand induced activation of the beta-receptor for platelet-derived growth factor (PDGF) leads to activation of Src family tyrosine kinases. We have explored the possibility that the receptor itself is a substrate for Src. We show that Tyr934 in the kinase domain of the PDGF receptor is phosphorylated by Src. Cell lines expressing a beta-receptor mutant, in which Tyr934 was replaced with a phenyal
Optimotaxis: A Stochastic Multi-agent on Site Optimization Procedure
We consider the problem of seeking the maximum of a scalar signal using a swarm of autonomous vehicles equipped with sensors that can take point measurements of the signal. Vehicles are not able to measure their current position or to communicate with each other. Our approach induces the vehicles to perform a biased random walk inspired by bacterial chemotaxis and controlled by a stochastic hybrid
Potential Risk Handling Alternatives for Supply Chain Disruptions in Liquid Food Production – the case of V&S Vin & Sprit AB, the Sundsvall site
V&S Sundsvall (a part of V&S Vin & Sprit AB) is a Swedish company producing different alcoholic beverages, mainly for the Swedish market. The company has lately paid increasing attention to supply chain disruption risk issues. In another study, one of the authors (Paulsson 2007) developed a model, called the DRISC (Disruption Risks In Supply Chains) model, for the structuring, evaluati
Site of action of endogenous endothelium-derived nitric oxide and of exogenous endothelin-1 along the vascular bed of skeletal muscle in vivo
No difference between daily and weekly pin site care
Energy partitioning between latent and sensible heat flux during the warm season at FLUXNET sites
Hässleberga – a Late Palaeolithic kill site in Scania, Sweden, confirmed by analysis of bone modifications
Late glacial skeletal remains from mainly reindeer and wild horse, but also other species such as mountain hare, arctic fox and elk have been collected from kettle holes in Hässleberga, Scania. Bones from reindeer and wild horse have been radiocarbon dated to Allerød and Younger Dryas. Analysis of bone modifications has revealed several different actors and factors behind the accumulation of the s
New excavations at the central site of Uppåkra, in the very south of Sweden
BVOC ecosystem flux measurements at a high latitude wetland site
A novel mutation on the transferrin gene abolishes one N-glycosylation site and alters the pattern of transferrin isoforms, mimicking that observed after excessive alcohol consumption.
In the process of obtaining a driver's license, a healthy 28year old man presented increased levels of disialo-transferrin (TF) (approx. 20%, ref. value<2) by HPLC analysis of TF isoforms (%CDT), while other markers of excessive alcohol consumption (PEth, MCV and γ-GT) were in the normal range. The objective of this study was to determine the cause of the increased %CDT levels.
Identification of covalent binding sites of ethyl 2-cyanoacrylate, methyl methacrylate and 2-hydroxyethyl methacrylate in human hemoglobin using LC/MS/MS techniques.
Acrylates are used in vast quantities, for instance in paints, adhesive glues, molding. They are potent contact allergens and known to cause respiratory hypersensitivity and asthma. Here we study ethyl 2-cyanoacrylate (ECA), methyl methacrylate (MMA) and 2-hydroxyethyl methacrylate (HEMA). There are only limited possibilities to measure the exposure to acrylates, especially for biological monitori
Review of ‘Sites of Violence: Gender and Conflict Zones’ (2004), W. Giles and J. Hyndman (eds.)
The proximal promoter of the human cathepsin G gene conferring myeloid-specific expression includes C/EBP, c-myb and PU.1 binding sites.
The A phenotype in the ABO blood group system is due to a splice-site mutation in a hybrid between a new O-like allelic lineage and the A allele.
Synthesis of New Polydentate Framework Ligands for Modelling of Biological Metal Sites
Fracture mapping using seismic amplitude variation with offset and azimuth analysis at the Weyburn CO2 storage site
Cap rock integrity is an essential characteristic of any reservoir to be used for long-term CO 2 storage. Seismic AVOA (amplitude variation with offset and azimuth) techniques have been applied to map HTI anisotropy near the cap rock of the Weyburn field in southeast Saskatchewan, Canada, with the purpose of identifying potential fracture zones that may compromise seal integrity. This analysis, su
