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Description and performance of an electron-ion coincidence TOF spectrometer used at the Brazilian synchrotron facility LNLS

This paper reports the characteristics and performance of a Time-of-Flight Mass Spectrometer (TOF-MS) for coincidence measurements between electrons and ions that has been developed jointly in Sweden and Brazil. The spectrometer, used for studies of inner-shell photoexcitation of molecules in the gas-phase, has been optimized by implementing ion and electron lenses to allow the use of relatively s

Thrombospondin-4 mediates cardiovascular remodelling in angiotensin II-induced hypertension

Thrombospondin 4 (TSP-4) expression is induced in the heart and vasculature under pathological conditions, including myocardial infarction, myocardial pressure overload, and hypertension. TSP-4 is linked to remodelling processes, where it may affect extracellular matrix protein organization. In previous work, we studied the role of TSP-4 in small arteries during hypertension using Ang II-treated T

Environmental Governance in China: Centralization of Local Environmental Policy in the Prevention and Control of Air Pollution in Key Regions plan

The purpose of the thesis is to showcase the affect environmental policy has on the centrallocal relations in contemporary China. The thesis argues that the central government is centralizing control of environmental policy by the use of the Prevention and Control of Air Pollution in Key Regions plan (Prevention Plan). The Prevention Plan introduces policies to enhance cooperation on a regional le

Legitimacy in municipal experimental governance : questioning the public good in urban innovation practices

Urban experiments, living labs and testbeds have emerged as influential approaches to governing cities around the world. Experimental governance allows stakeholders to trial possible futures and to embrace creativity and innovation in the pursuit of sustainability goals. Experiments are often conducted through triple helix partnerships that favour informal and distributed actions. This is a signif

Targeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets

Mantle cell lymphoma (MCL) is an aggressive B-cell neoplasm that follows a heterogeneous clinical course. Recurrent mutations have been described, but their applicability in the clinical setting is currently limited. The main reasons are challenges in the sequencing of DNA retrieved from formalin-fixed tissue commonly used for tissue collection in clinical biobanks. In this study, we sequenced 77

Attosecond transient absorption spectroscopy of helium above the N=2 ionization threshold

Attosecond transient absorption spectroscopy (ATAS) allows for the study of electron dynamics in atoms and molecules with attosecond time resolution. Previous works reported in the literature have made use of ATAS to image and control such dynamics in the single-channel ionization continuum of helium; in particular, in the vicinity of the doubly excited autoionizing states lying between the N=1and

[P]ers[on]a mis[ce]lanea : Works of Manuel Ponce by Bertrand Chavarría-Aldrete

This release brings together some of Ponce’s finest guitar works, carefully selected and sensitively performed by Bertrand Chavarría-Aldrete. The album opens with a Preludio written not long after Ponce arrived in Paris, characterised by modal and whole tone inflections that lend the piece an impressionistic quality. The release also includes the later set of Seis preludios cortos (‘Six short prel

Ignorance is Bliss? Tracing the Process of Democratic Transition in Argentina with a Gender Perspective

This bachelor thesis focuses on the democratic transition in Argentina in the begin¬ning of the 1980s and aims to expose several variables within this political develop¬ment by using a method of process tracing. What many scholars have failed to notice is the role that women's movements in Latin America have had in this process. The authoritarian regime in Argentina also failed to acknowledge

Framing brain drain : between solidarity and skills in European labor mobility

How do crisis perceptions interrelate with the emergence and re-constitution of policy problems? By using a novel combination of interviews with a content and network analysis of hand-coded parliamentary questions, this article maps the emergence of brain drain as a policy problem at the level of the European Union and follows the evolution of the issue over the last four parliamentary periods (fr

Disentangling the Environmental Factors That Shape Genetic and Phenotypic Leaf Trait Variation in the Tree Qualea grandiflora Across the Brazilian Savanna

Identifying the environmental factors that shape intraspecific genetic and phenotypic diversity of species can provide insights into the processes that generate and maintain divergence in highly diverse biomes such as the savannas of the Neotropics. Here, we sampled Qualea grandiflora, the most widely distributed tree species in the Cerrado, a large Neotropical savanna. We analyzed genetic variati

Smart and sustainable cities? : pipedreams, practicalities and possibilities

Smart cities promise to generate economic, social and environmental value through the seamless connection of urban services and infrastructure by digital technologies (Hollands 2008, Viitanen and Kingston 2014), but there is scant evidence concerning their ability to enhance social well-being, build just and equitable communities, reduce resource consumption and waste generation, improve environme

Change in different classes of chronic back pain suspicious of axial spondyloarthritis : A latent transition analysis of the SPACE cohort

Objectives To follow up four previously identified classes 'pure axial spondyloarthritis' (axSpA) ('axial'), 'axSpA with peripheral signs' ('inflammatory back pain+peripheral'), 'axSpA at risk' and 'no spondyloarthritis' ('no SpA'). They reflect the expert-opinion-free construct or 'Gestalt' of chronic back pain suspicious of axSpA. The aim was to assess participants' transitions between these cla

Amyloid-β deposition predicts oscillatory slowing of magnetoencephalography signals and a reduction of functional connectivity over time in cognitively unimpaired adults

With the ongoing developments in the field of anti-amyloid therapy for Alzheimer’s disease, it is crucial to better understand the longitudinal associations between amyloid-β deposition and altered network activity in the living human brain. We included 110 cognitively unimpaired individuals (67.9 ± 5.7 years), who underwent [18F]flutemetamol (amyloid-β)-PET imaging and resting-state magnetoenceph

ADULTS AS ADVOCATES : HOW SEXUAL ABUSE WAS PUT ON THE CHILD RIGHTS MAP IN INDIA

Is more child participation always better for child rights advocacy? That is the question I examine, in this chapter, as I analyse advocacy for child rights in India that led to the adoption of the landmark Protection of Children from Sexual Offences Act, 2012 (the ‘POCSO Act’). Through ethnographic fieldwork with non-government organisations (NGOs) and a narrative analysis of interviews and aware

Radial distortion triangulation

This paper presents the first optimal, maximal likelihood, solution to the triangulation problem for radially distorted cameras. The proposed solution to the two-view triangulation problem minimizes the L2-norm of the reprojection error in the distorted image space. We cast the problem as the search for corrected distorted image points, and we use a Lagrange multiplier formulation to impose the ep

Assemblage-democracy : Reconceptualising democracy through material resource governance

This article furthers political geographic thinking on democracy by generating and employing a conceptualisation of ‘assemblage-democracy’. Bringing an assemblage perspective to democratic thinking brings to the fore three key dimensions: the co-constitution of material and non-material connections; connectivity and associations, in particular engagement with multiple heterogeneous ‘minoritarian’

A Population-Based Multigenerational Family Coaggregation Study of Severe Infections and Obsessive-Compulsive Disorder

Background: Postinfectious autoimmune processes have been proposed as potential causal risk factors for obsessive-compulsive disorder (OCD). In this large population-based study, we aimed to clarify the familial coaggregation pattern between severe infections and OCD across clusters of relatives with varying degrees of relatedness. Methods: We identified 4,916,898 individuals born in Sweden betwee