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Microsoft Word - Discovery of dopamine.doc 1 The Discovery of Dopamine Dopamine as an independent neurotransmitter in the nervous system was discovered in Lund by the pharmacologist Arvid Carlsson in 1957, working at the Department of Pharmacology at Sölvegatan 10 in Lund (the current Geocentrum building). This discovery had tremendous impact on modern neuroscience research and – in combination wi

https://www.neuroscience.lu.se/sites/neuroscience.lu.se/files/the_discovery_of_dopamine_pdf.pdf - 2026-07-13

Background: Thrombomodulin (TM) is predominantly a vascular endothelial cell plasma membrane glycoprotein that, via distinct structural domains, interacts with multiple ligands, thereby modulating coagulation, fibrinolysis, complement activation, inflammation and cell proliferation. We previously reported that by mediating signals that interfere with mitogen-activated protein kinase and nuclear fa

Mixtures of powders of platinum with nickel or cobalt to obtain Ni0.75Pt0.25 or Co0.75Pt0.25 were mechanical alloyed by high energy ball milling. The results of crystal structure, morphology and electrocatalytic performance are presented for mechanically activated powders after 3 and 9 h of ball milling. Total solid solutions of Ni and Co with platinum were analyzed by X-ray diffraction after 3 h

The present article is a functional analysis of intonation in Russian declarative utterances. Pragmatically relevant tonal patterns and their functions are identified and described. Utterances are analysed in terms of theme and rheme. Theme is signalled by a tonal rise and rheme by a falling tonal gesture. Beside thematic and rhematic tonal gestures, other rising accents in the utterance are ident

Objectives To determine whether three-dimensional (3D) ultrasound including power Doppler examination of the cervix is useful for predicting time to spontaneous onset of labor or time to delivery in prolonged pregnancy. Methods A prospective study was conducted in 60 women who went into spontaneous labor. All underwent transvaginal 3D power Doppler ultrasound examination of the cervix immediately

A hypothesis regarding the mechanism causing salt frost scaling on Portland cement-bound materials is described. It is assumed that deterioration is due to osmotic micro ice body growth, as has been previously proposed for frost deterioration of moisture-isolated specimens of cement-bound materials. In moisture-isolated specimens, this ice body growth stops when the micro structure is drained to a

The purpose of this paper is to compare pension schemes with respect to their intergenerational redistributive effects caused by economic and demographic changes. It is shown how these effects depend on the specific design of the pension scheme, with special attention devoted to the indexation problem. There is a potential trade-off between financial stability of the pension system and a “desired”

This paper discusses processes of emotionalisation and commodification at home and work, a theme that has been a focus of Arlie Hochschild’s research in the USA over the last four decades. What happens when you look at similar processes within another national frame? The American experience is contrasted to that of two periods of rapid cultural and economic change in Swedish society during the ear

This paper introduces a suite of tests for linear and general non- linear serial dependence. The problem is complex as the number of variations of realistic non-linear alternatives is very large. The alternative model is dened in terms of penalized truncated polynomial splines, making the approximation capable of accurately approximating a large class of linear and non-linear processes. The asympt

Child labour is born out of poverty, and it leads to more poverty. Those that work from a young age often have no possibility of going to school, and can only perform manual work as adults, which often pays little. Many children face considerable risks in their place of employment. Some of them suffer from short-term health problems, but others develop cancers and other serious diseases as a resul

Arbetet undersöker och analyserar hur utomståenderegeln förhåller sig till begreppet samma eller likartad verksamhet vid tillämpning av de särskilda fåmansföretagsreglerna. Vidare utrönas det gällande rättsläget för vartdera bestämmelse, vilket har sin utgångspunkt i lagstiftning och förarbeten. Mycket utrymme har sedan givits till praxis då de båda bestämmelsernas rekvisit, samt bestämmelsernas tThe thesis aims to examine and analyze how the outsider rule (swe. Utomståenderegeln) relates to the concept of conducting same or similar activities (swe. Samma eller likartad verksamhet) within the swedish taxation laws regarding closely held companies (swe. fåmansföretagsreglerna). Furthermore, the current legal situation for each provision is ascertained, which is based on legislation and prep

The purpose of our thesis has been to increase the knowledge about the need of investigating children who may have ADHD in order to contribute to more children receiving the support and understanding they need to be able to succeed in school. In our research, we have investigated which initiator that initiates ADHD investigations in the majority of cases for children in primary school and elementa

Drawing on post-political theory the thesis explores the changes in the role of politics within the framework of the Swedish governmental commissions. The findings of the thesis show that the function of politics in the Swedish governmental commissions has shifted from a means to achieve consensus through the creation of policy despite the antagonistic nature of the political to a means to exclude