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The main objective of Work Package 4 was to provide quantifiable evidences of the potential role of CNH as a driver for sustainable growth. To do this, WP4 has been monitoring over the last 2.5 years the performance of the deployed Action Plans (or regeneration schemes) in the 6 initial Replicators (Rs), and the 9 Additional Replicators (ARs) included in the last phase of the project. Performance’
The podocyte is a specialized cell type critically involved in maintaining the selective filtration barrier of the kidney. Podocytes are primary or secondary targets for a multitude of kidney diseases. Despite intense investigation, the transcriptome and proteome of human podocytes remain incompletely characterized. Here, we analyzed publicly available RNA-Seq data from human kidneys (n = 85) to c
Rural communities tell us the story of a thousand of years of collaboration between nature, culture and humans. The current Covid-19 pandemic is considerably threating rural areas, posing challenges exacerbated by low available financial resources, not easily accessible health services and greater isolation. Rural areas are also considered safe shelters characterized by better daily living conditi
A key assumption conventionally made by flexible head-mounted eye-tracking systems is often invalid: The eye center does not remain stationary w.r.t. the eye camera due to slippage. For instance, eye-tracker slippage might happen due to head acceleration or explicit adjustments by the user. As a result, gaze estimation accuracy can be significantly reduced. In this work, we propose Grip, a novel g
Dry, wet, dense, and dilute granular flows have been previously considered fundamentally different and thus described by distinct, and in many cases incompatible, rheologies. We carry out extensive simulations of granular flows, including wet and dry conditions, various geometries and driving mechanisms (boundary driven, fluid driven, and gravity driven), many of which are not captured by standard
The 1.87–1.84 Ga Black Hills dike swarm of the Kalahari craton (South Africa) is coeval with several regional magmatic provinces used here to resolve the craton’s position during Columbia assembly. We report a new 1850 ± 4 Ma (U-Pb isotope dilution–thermal ionization mass spectrometry [ID-TIMS] on baddeleyite) crystallization age for one dike and new paleomagnetic data for 34 dikes of which 8 have
The production of 1 ton of PVC requires 2.0 - 2.5 m3 of demineralised water. Some of the water is lost in the process, e.g. as vapor during the drying of the PVC or as sealing water, while approx. 80% of the water could potentially be recycled. In today’s installations only about 20 – 25% of the water recovered by the PVC decanter is used for flushing of the facilities, while 75 – 80% is discharge
Tolerance induction, and thus prevention of autoimmunity, is linked with the amount of self-antigen presented on thymic stroma. We describe that intrathymic (i.t.) delivery of the autoantigen, myelin oligodendrocyte glycoprotein (MOG), via a lentiviral vector (LV), led to tolerance induction and prevented mice from developing fulminant experimental autoimmune encephalomyelitis (EAE). This protecti
OBJECTIVE: Changes in ECG-derived parameters are studied in atrial fibrillation (AF) patients undergoing cryoballoon catheter ablation.APPROACH: Parameters characterizing f-wave frequency, morphology by phase dispersion, and amplitude are estimated using a model-based statistical approach. These parameters are studied before, during, and after ablation, as well as for AF type (paroxysmal/persisten
The Common Correlated Effects (CCE) methodology is now well established for the analysis of factor-augmented panel models. Yet, it is often neglected that the pooled variant is biased unless the cross-section dimension (N) of the dataset dominates the time series length (T). This is problematic for inference with typical macroeconomic datasets where T often equal or larger than N. Given that an an
Since the Oslo Accords, the two-state solution has dominated, and frustrated, the official search for peace in Palestine/Israel. In parallel to it, an alternative struggle of resistance—centred upon the single-state idea as a more liberating pathway towards justice to the conflict—has re-emerged against the hegemony of Zionism and the demise of a viable two-state solution in Palestine/Israel. This
Granule neurons of the dentate gyrus (DG) of the hippocampus undergo continuous renewal throughout life. Among cell cycle regulators, cyclin-dependent kinase 2 (Cdk2) is considered as a major regulator of S-phase entry. We used Cdk2-deficient mice to decipher the requirement of Cdk2 for the generation of new neurons in the adult hippocampus. The quantification of cell cycle markers first revealed
The aim of the present study is to examine and describe Swedish upper secondary students’ use of their background languages while translating a text from Italian, a language unknown to them, into either their L2 English or their L3 French or Spanish. The assumption here is that searching for similarities between these languages is a natural feature of language learning and that intercomprehension
