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BackgroundIn a previous phase II trial, intraperitoneal local anaesthetics shortened the time interval between surgery and adjuvant chemotherapy, an endpoint associated with improved survival in advanced ovarian cancer. Our objective was to test this in a phase III trial.MethodsA double-blind, phase III parallel superiority trial was conducted at two university hospitals in Sweden, within a public

In analyses of affordances and opportunities in different neighbourhoods it is found that access to public buildings and a well-functioning public space are of outmost importance. This is found to be especially important in neighbourhoods having a population with fewer resources, areas often discussed in terms as ‘deprived’ or ‘excluded’, concepts that alludes to the phenomenon of segregation. Pre

Purpose: The purpose is to investigate how the coronavirus disease 2019 (COVID-19) pandemic changed relocation behavior in an advanced economy. We compare manufacturing relocations before and during the pandemic to identify differences and similarities over time and between offshoring and backshoring. Design/methodology/approach: We use an exploratory longitudinal trend survey approach with data f

Ett nytänk behövs för våra cykelvägar! Våra växande städer är helt uppbyggda kring transporter med bil. För att kunna bromsa klimatförändringarna behöver vi tänka nytt. Färre bilar och fler cyklar är en av lösningarna som förts fram allt oftare på senare år. Köpenhamn och Amsterdam är de städer som nått längst i att få människor att cykla i stället för att ta bilen. Ju vanligare cyklar blir i trafIn several other European countries, the number of electric bikes (pedelecs) has increased significantly in recent years. A similar increase is also expected in Sweden. So far the knowledge of the attitudes of people using electric bikes in Sweden are limited. This study consists of interviews with 39 persons from all around Sweden to get a better understanding of why they have chosen to ride an e

Prisutvecklingen på den svenska bostadsmarknaden har under de senaste åren varit positiv. Lågt bostadsbyggandet i förhållande till befolkningsökningen anses vara en bidragande orsak till den positiva prisutvecklingen. Ett sätt att mäta attraktiviteten på den lokala bostadsmarknaden är Tobins Q. På småhusmarknaden definieras Tobins Q vanligtvis som kvoten mellan ett småhus marknadsvärde och dess iOne way to measure the attractiveness of a local housing market is Tobin’s Q. On the market for single-family housing property, Tobin’s Q is usually defined as the ratio between the market value of the property and its investment cost. This means that the quota can serve as an indicator on whether it is profitable to build a new house or not. The theory states that Tobin’s Q above 1,0 indicates th

Idrottsrörelsen med fotboll i fokus har kommit att förändra sin struktur avsevärt under 1900-talet. Fotbollen har gått från att vara en ideell verksamhet med syfte att samla de lokala invånarna för att utöva sporten till en miljardindustri inom Europa. EU:s konkurrensregler har kommit att spela en viktig roll för att främja idrottens utveckling samt förhindra att marknaden snedvrids genom ekonomisSport movement especially football has change its structure of the sport drastically during the 20th century. Football has transformed from being a non-profit activity with one of its purpose to gather the locals for a friendly game to a multibillion industry within Europe. EU: s competition law has played a crucial part to maintain the development for sport and to prevent distortion of competitio

Various environmental forcings can affect phytoplankton blooms, resulting in changes in bloom timing and abundance, which can have many far-reaching consequences. Understanding bloom phenology is crucial to predict and counter any potential harmful changes. The North Sea is an important fishing ground, and any changes in phytoplankton bloom patterns can have a significant impact on the region'

Gender and sexual minority groups in Nepal, Bangladesh, and India have been systematically discriminated against in their States and ignored by the international community, for decades. While the three States have made progress concerning legal gender recognition, including recognizing a third gender on specific documents such as passports or identification cards, issues remain in ensuring equalit

Bin i södra Indien Vilda bin är mycket viktiga för både vilda blommor och grödor, eftersom de hjälper till att pollinera dem så att de kan bilda frön och sätta frukt. Över hela världen har dock antalet vilda bin minskat vilket kan innebära problem för både ekosystem och jordbruket. En stor orsaken till minskningarna är att jordbrukslandskap har intensifierats, vilket har gjort att landskapet har 1. Wild bees are very important for pollination of both wild flowers and agricultural crops, benefitting seed set and yields. However, declines in bee populations have been observed across the world and it has been proposed that the intensification of agriculture including landscape simplification by loss of natural habitats, is a major reason for these declines. India is undergoing large-scale ag

The connection of devices to the internet is referred to as Internet of Things (IoT). By using IoT distributed network of devices will be able to communicate with each other. The management and forming of distributed applications is, however, very complex since IoT uses devices that have different capabilities and that do not have the same communication protocols. Calvin is an open source applicat

Lowering global carbon emission is one of the most pressing issues of our time. A rising interest in the role of cities in lowering emissions has been detected. Although urban areas are active entities in the production of carbon emissions they are also potential hubs for designing and implementing solutions. Such processes has been referred to as urban low carbon transitions (ULCT) by academics.

This thesis explores the problem of domestic violence in Ghana from a socio-legal perspective. It investigates the tensions that arise from the application of customary and state law in order to understand why domestic violence, persist and continues being prevalent in communities in Ghana. It draws on living law theory. Based on a multi-sited research qualitative design, interviews were conducted

Varierande likhet i blomdoft – beror det på släktskapsband? De senaste decennierna har kunskapen om blomdoft och dess betydelse i interaktioner mellan växter och insekter ökat avsevärt. Det finns en stor mängd olika doftämnen i blommors doft och blomdoften kan vara högst variabel, inte bara mellan arter utan också mellan individer av samma art. Även om vissa doftämnen verkar sakna ekologisk funktUnderstanding the evolutionary processes behind intraspecific variation and population differentiation is an important topic in biology, since intraspecific variation is required for speciation. Angiosperms show fascinating diversity in flower designs. Since the flower is crucial for reproductive success and at the same time often involved in biotic interactions with pollinators and/or herbivores,

How does the likelihood of encountering wildlife affect residents’ expectations about psychological restoration when visiting a local natural setting, and their choices among settings for future recreation? Do urban and rural residents differ in such expectations and choices? We addressed these questions in a web-based experiment with 223 adult residents randomly sampled from urban and rural areas

Background Vitamin D insufficiency (VDI) may be a factor in the development of type 1 diabetes (T1D). The aim of this study is to investigate the presence and persistence of VDI in a large cohort of infants with increased risk of developing T1D, in light of the differences in local supplementation guidelines. Methods In the POInT Study, a multicentre primary prevention study between February 2018

We investigate a model for opinion dynamics, where individuals (modeled by vertices of a graph) hold certain abstract opinions. As time progresses, neighboring individuals interact with each other, and this interaction results in a realignment of opinions closer towards each other. This mechanism triggers formation of consensus among the individuals. Our main focus is on strong consensus (i.e., gl

We evaluate a place-based policy aimed at commercial service providers. In 2016, the Swedish government introduced special operating support for grocery stores in remote rural areas to slow down the process of store closures. We estimate the local causal effect in a regression discontinuity design framework using the fact that only stores located at least 15 km away from another store were eligibl

BACKGROUND AND AIMS: Vedolizumab is a gut-selective treatment approved for Crohn's disease (CD) and ulcerative colitis (UC). Recently, a subcutaneous formulation of vedolizumab was approved. The aims of this study were to evaluate efficacy, safety, pharmacokinetics, patient experience and costs following a switch from intravenous to subcutaneous vedolizumab treatment.METHODS: Patients were switche

Mobility is one of the most fundamental aspects of a foraging society. Since prehistoric mobility is often difficult to identify in the archaeological record, our understanding is largely based on comparison with ethnographic communities. In recent years the application of 87Sr/86Sr isotope analysis has, however, greatly broadened our knowledge of mobility in the past. Despite this, few studies ha

Ecosystem-based protection is becoming a viable adaptation option to conventional engineered solutions to rising sea levels and coastal erosion. While the environmental and biological ecosystem services provided by ecosystem-based adaptation measures such as beach nourishment and/or seagrass plantations are being acknowledged and analysed, less attention has been paid to the social or cultural dim